Cell-fate choice in Dictyostelium: Intrinsic biases modulate sensitivity to DIF signaling

Developmental Biology

Volumn 227, Issue 1, 2000, Pages 56-64

  Thompson, Christopher R L ^a   Kay, Robert R ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Cell fate choice; Cell signaling; Dictyostelium; DIF; Intrinsic bias

Indexed keywords

CELL MARKER; GLUCOSE;

ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL FATE; CELL INTERACTION; DICTYOSTELIUM; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPOROGENESIS;

DICTYOSTELIUM;

EID: 0034331234     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.2000.9877     Document Type: Article

References (55)

1. Precise expression of the cAMP receptor gene, car1, during transition from growth to differentiation in Dictyostelium discoideum
2. Production and activity of spore differentiation factors (SDFs) in Dictyostelium
3. Cell-cycle-dependent sorting in the development of Dictyostelium cells
4. Integration of signaling networks that regulate Dictyostelium differentiation
5. 2+ in Dictyostelium discoideum
6. 2+-dependent early functional heterogeneity in amoebae of Dictyostelium discoideum, revealed by flow cytometry
7. Cyclic AMP is an inhibitor of stalk cell differentiation in Dictyostelium discoideum
8. Combinatorial control of cell differentiation by cAMP and DIF-1 during development of Dictyostelium discoideum
9. The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal fates
10. Initial cell-type choice in a simple eukaryote: Cell-autonomous or morphogen-gradient dependent?
11. Optimization and in situ detection of Escherichia coli beta-galactosidase gene expression in Dictyostelium discoideum
12. Evidence for positional differentiation of prestalk cells and for a morphogenetic gradient in Dictyostelium
13. Two distinct populations of prestalk cells within the tip of the migratory Dictyostelium slug with differing fates at culmination
14. A Dictyostelium prespore-specific gene is transcriptionally repressed by DIF in vitro
15. cAMP and cell sorting control the spatial expression of a developmentally essential cell-type-specific ras gene in Dictyostelium
16. Chemoattractant-controlled accumulation of coronin at the leading edge of Dictyostelium cells monitored using green fluorescent protein-coronin fusion protein
17. A cell-cycle phase-associated cell-type choice mechanism monitors the cell cycle rather than using an independent timer
18. Cell-autonomous determination of cell-type choice in Dictyostelium development by cell-cycle phase
19. Developmental decisions in Dictyostelium discoideum
20. Intracellular pH and the control of cell differentiation in Dictyostelium discoideum
21. The metabolism of macromolecules during the differentiation of myxamoebae of the cellular slime mould Dictyostelium discoideum containing different amounts of glycogen
22. Cells at the center of Dictyostelium aggregates become spores
23. Correlations between prestalkprespore tendencies and cAMP-related activities in Dictyostelium discoideum
24. DIF-1 induces its own breakdown in Dictyostelium
25. Maggot's hair and Bug's eye: Role of cell interactions and intrinsic factors in cell fate specification
26. Cell differentiation in monolayers and the investigation of slime mold morphogens
27. Evidence that elevated intracellular cyclic AMP triggers spore maturation in Dictyostelium
28. The biosynthesis of differentiation-inducing factor, a chlorinated signal molecule regulating Dictyostelium development
29. Morphogen hunting in Dictyostelium
30. DIF signalling and cell fate
31. A possible morphogen controlling differentiation in Dictyostelium
32. DIF-resistant expression of a prespore-specific gene in Dictyostelium in vitro development
33. Cell sorting out during the differentiation of mixtures of metabolically distinct populations of Dictyostelium discoideum
34. Lateral inhibition and pattern formation in Dictyostelium
35. Transplantation experiments and pattern mutants in cellular slime mold slugs
36. A new method for inducing synchronous growth of Dictyostelium discoideum cells using temperature shifts
37. Heterogeneity of the cell population of the cellular slime mold Dictyostelium discoideum before aggregation, and its relation to the subsequent locations of the cells
38. Fractionation of the differentiated types of cells constituting the pseudoplasmodia of the cellular slime molds
39. The cell cycle and sorting behaviour in Dictyostelium discoideum
40. A secreted factor and cyclic AMP jointly regulate cell-type-specific gene expression in Dictyostelium discoideum
41. Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum
42. Differentiation-inducing-factor dechlorinase, a novel cytosolic dechlorinating enzyme from Dictyostelium discoideum
43. Pseudoplasmodium formation and organization in Dictyostelium discoideum
44. Cell type conversion in isolated prestalk and prespore fragments of the cellular slime mold Dictyostelium discoideum
45. Interactions between adenosine and oscillatory cAMP signaling regulate size and pattern in Dictyostelium
46. Establishment of polar organization during slime mold development
47. Role of cell sorting in pattern formation in Dictyostelium discoideum
48. Cell differentiation without morphogenesis in Dictyostelium discoideum
49. Cell cycle phase in Dictyostelium discoideum is correlated with the expression of cyclic AMP production, detection, and degradation
50. Ammonia depletion and DIF trigger stalk cell differentiation in intact Dictyostelium discoideum slugs
51. Growth of myxamoebae of the cellular slime mould Dictyostelium discoideum in axenic culture
52. Dependence of cell-type proportioning and sorting on cell cycle phase in Dictyostelium discoideum
53. Separation of Dictyostelium discoideum cells into density classes throughout their development and their relationship to the later cell types
54. Direct induction of Dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen
55. Origins of the prestalk-prespore pattern in Dictyostelium development