Regulation of endothelial CD73 by adenosine: Paracrine pathway for enhanced endothelial barrier function

Journal of Immunology

Volumn 165, Issue 9, 2000, Pages 5262-5268

  Narravula, S ^a   Lennon, P F ^a   Mueller, B U ^a   Colgan, S P ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE A2B RECEPTOR; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; DNA; ECTO 5' NUCLEOTIDASE; NUCLEOTIDE;

ARTICLE; BIOTINYLATION; CELL JUNCTION; CONCENTRATION RESPONSE; DNA BINDING; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ACTIVATION; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; TRANSCRIPTION INITIATION;

EID: 0034327277     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.9.5262     Document Type: Article

References (46)

1. Nucleotide metabolism by endothelium
2. 5'-Nucleotidase: Molecular structure and functional aspects
3. Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia
4. Neutrophil-derived 5'-adenosine monophosphate promotes endothelial barrier function via CD73-mediated conversion to adenosine and endothelial A(2B) receptor activation
5. Adenosine receptors
6. Energetic response of coronary endothelial cells to hypoxia
7. 5'-Adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayers
8. CD73 is involved in lymphocyte binding to the endothelium: Characterization of lymphocyte-vascular adhesion protein 2 identifies it as CD73
9. Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73)
10. The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia
11. Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties
12. Isolation and characterization of the promoter of the human 5'-nucleotidase (CD73)-encoding gene
13. Transcriptional regulation by cyclic AMP
14. Adenosine promotes regulation of corneal hydration through cyclic adenosine monophosphate
15. 6-etheno-AMP as substrate, and comments on the properties of the reaction product, ethenoadenosine
16. Hypoxia enhances endotoxin-stimulated induction of functional intercellular adhesion molecule-1 (ICAM-1)
17. Interactions between cyclosporine A and adenosine in kidney transplant recipients
18. Nomenclature and classification of purinoceptors
19. 6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A3 adenosine receptors
20. Ecto-enzyme and signaling functions of lymphocyte CD73
21. Ecto-5'-nucleotidase (CD73): Genomic cloning and characterization of regions upstream of the translation start site
22. Signal transduction and gene control: The cAMP pathway
23. Differential regulation and function of CD73, a glycosyl-phosphatidylinositol-linked 70-kD adhesion molecule, on lymphocytes and endothelial cells
24. Stage-specific expression of P2Y receptors, ecto-apyrase, and ecto-5'- nucleotidase in myeloid leukocytes
25. Tissue-specific regulation of the ecto-5'-nucleotidase promoter: Role of the camp response element site in mediating repression by the upstream regulatory region
26. Ecto-ATPases: Identities and functions
27. Characterization of the adenosine receptor in microvascular coronary endothelial cells
28. Stimulation of the mitogen-activated protein-kinase via the A(2A)-adenosine receptor on primary human endothelial cells
29. 2 receptor-cAMP system in human aortic endothelial cells
30. 2-Adenosine receptor stimulation increases macromolecular permeability of coronary endothelial cells
31. Hypoxia induces phosphorylation of the cyclic AMP response element-binding protein by a novel signaling mechanism
32. Critical role of cAMP response element binding protein expression in hypoxiaelicited induction of epithelial TNFα
33. 5'-Nucleotidase inhibitors and the myocardial reactive hyperemia and adenosine content
34. Cardioprotection due to preconditioning correlates with increased ecto-5'-nucleotidase activity
35. Cardioprotection by ischemic preconditioning: Role of adenosine and glycogen
36. Role of adenosine A(1) receptors in modulating extracellular adenosine levels
37. Endothelial cell-to-cell junctions
38. Endothelial cells: Adhesion and tight junctions
39. Regulation of vascular endothelial barrier function
40. Involvement of myosin light-chain kinase in endothelial cell retraction
41. 2+ corresponds with myosin phosphorylation in pulmonary artery endothelial cells
42. Histamine and thrombin modulate focal adhesion through centripetal and centrifugal forces
43. Roles of calcium, cyclic nucleotides, and protein kinase C in regulation of endothelial permeability
44. Dysfunction of cGMP-mediated pulmonary vasorelaxation in endotoxin-induced acute lung injury
45. Cytokine-induced VCAM-1 and ICAM-1 expression in different organs of the mouse
46. Adenosine, an endogenous anti-inflammatory agent