Successful implementation of automation in medicinal chemistry

Drug Discovery Today

Volumn 5, Issue 11, 2000, Pages 521-527

  Coates, William J ^a   Hunter, David J ^a   MacLachlan, William S ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOMATION; CHEMISTRY; DRUG MANUFACTURE; DRUG RESEARCH; EQUIPMENT; REVIEW; ROBOTICS; TECHNOLOGY;

EID: 0034326432     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(00)01571-3     Document Type: Review

References (14)

1. Changes in scale in automated pharmaceutical research
2. Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries
3. Automated synthesis: New tools for the organic chemist
4. Applications of small-molecule combinatorial chemistry to drug discovery
5. Drug discovery and vaccine development using mixture-based synthetic combinatorial libraries
6. Uptake of new technology in lead optimisation for drug discovery
7. A business to bank on
8. Object-relational databases: The next wave in pharmaceutical data management
9. Combinatorial chemistry and molecular diversity. An overview
10. The development of a solid phase Tsuge reaction and its application in high throughput robot synthesis
11. Synthesis of an array of potential matrix metalloproteinase inhibitors using a sequence of polymer-supported reagents
12. Radiofrequency encoded combinatorial chemistry
13. Quantitation of combinatorial libraries of small organic molecules by normal-phase HPLC with evaporative light-scattering detection
14. Separating the wheat from the chaff: High throughput purification of chemical libraries