Nitric oxide generation in a rat model of acute portal hypertension

American Journal of Veterinary Research

Volumn 61, Issue 10, 2000, Pages 1173-1177

  Howe, Lisa M ^a   Boothe, Dawn M ^a   Slater, Margaret R ^a   Boothe, Harry W ^a   Wilkie, Scott ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

NITRIC OXIDE;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIOSYNTHESIS; BLOOD; BODY TEMPERATURE; BREATHING; DISEASE MODEL; DOG; DOG DISEASE; HEART RATE; MALE; METABOLISM; PATHOPHYSIOLOGY; PORTAL HYPERTENSION; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; BODY TEMPERATURE; DISEASE MODELS, ANIMAL; DOG DISEASES; DOGS; HEART RATE; HYPERTENSION, PORTAL; MALE; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION;

EID: 0034303330     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2000.61.1173     Document Type: Article

References (45)

1. Feldman PL, Griffith OW, Stuehr DJ. The surprising life of nitric oxide. C & EN 1993;20:26-38.
2. Ignarro LJ. Endothelium-derived nitric oxide: actions and properties. FASEB J 1989;3:31-36.
3. Schmidt HW, Waller U. NO at work. Cell 1994;78:919-925.
4. Nathan C, Xic QW. Nitric oxide symhases: roles, tolls, and controls. Cell 1994;78:915-918.
5. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992;6:3051-3064.
6. Moncada S. The L-arginine: nitric oxide pathway. Acta Physiol Scand 1992;145:201-227.
7. Thiemermann C, Ruetten H, Wu C, et al. The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase. Br J Pharmacol 1995;116:2845-2851.
8. Petros A, Bennett D, Vallance P. The effect of nitric oxide synthase inhibitors in hypotension in patients with septic shock. Lancet 1991;338:1557-1558.
9. Petros A, Lamb G, Leone A, et al. Effects of nitric oxide synthase inhibitor in humans with septic shock. Cardiovasc Res 1994;28:34-39.
10. Stichtenoth DO, Frolich JC. Nitric oxide and inflammatory joint diseases. Br J Rheumalol 1998;37:246-257.
11. Clancy RM, Amin AR, Abramson SB. The role of nitric oxide in inflammation and immunity. Arthritis Rheum 1998;41:1141-1151.
12. Stefanovic-Racic M, Stadler J, Evans CH. Nitric oxide and arthritis. Arthritis Rheum 1993;36:1036-1044.
13. Lala PK. Significance of nitric oxide in carcinogenesis, tumor progression and cancer therapy. Cancer Met Rev 1998;17:1-6.
14. Whiting PG, Peterson SL. Portosystemic shunts. In: Slatter D, ed. Textbook of small animal surgery. 2nd ed. Philadelphia: WB Saunders Co, 1993;660-677.
15. Butler LM, Fossum TW, Boothe HW. Surgical management of extrahepatic portosystemic shunts in the dog and cat. Semin Vet Med Surg (Small Anim) 1990;5:127-133.
16. Tobias KMS, Seguin B, Johnston G. Surgical approaches to single extrahepatic portosystemic shunts. Compend Contin Educ (Small Anim Pract) 1998;20:593-601.
17. Vogt JC. Krahwinkel DJ, Bright RM, et al. Gradual occlusion of extrahepatic portosystemic shunts in dogs and cats using the ameroid constrictor. Vet Surg 1996;25:495-502.
18. Bernadich C, Bandi JC, Piera C, et al. Circulatory effects of graded diversion of portal blood flow to the systemic circulation in rats: role of nitric oxide. Hepatology 1997;26:262-267.
19. Pilette C, Kirstetter P, Sogni P, et al. Dose-dependent effects of nitric oxide biosynthesis inhibitor on hyperdynamic circulation in two models of portal hypertension in conscious rats. J Gastroenterol Hepatol 1996;11:1-6.
20. Pizcueta P, Pique JM, Fernandez M, et al. Modulation of the hyperdynamic circulation of cirrhotic rats by nitric oxide inhibition. Gastroenterology 1992;103:1909-1915.
21. Hampl V, Walters CL, Archer SL. Determination of nitric oxide by the chemiluminescence reaction with ozone. In: Feelisch M, Stamler JS, eds. Methods in nitric oxide research. West Sussex, England: Wiley, 1996;309-318.
22. Furchgott RF, Zawadski JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980;288:373-376.
23. Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987;327:524-526.
24. Kanner J, Harel S, Granit R. Nitric oxide as an antioxidant. Arch Biochem Biophys 1991;289:130-136.
25. Gross SS, Wolin MS. Nitric oxide: pathophysiological mechanisms. Ann Rev Physiol 1995;57:737-769.
26. Stamler JS, Singel DJ, Loscalzo J. Biochemistry of nitric oxide and its redox-activating forms. Science 1992;258:1898-1902.
27. Moncada S, Higgs EA. Endogenous nitric oxide: Physiology, pathology and clinical relevance. Eur J Clin Invest 1991;21:361-374.
28. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathology and pharmacology. Pharm Rev 1991;43:109-142.
29. Thiemermann C. The role of the L-arginine: nitric oxide pathway in circulatory shock. Adv Pharmacol 1994;28:45-79.
30. Quinn AC, Petros AJ, Vallance P. Nitric oxide: an endogenous gas. Br J Anesth 1995;74:443-451.
31. Forstermann U, Schmidt HHHW, Pollock J, et al. Isoforms of nitric oxide synthase: characterization and purification from different cell types. Biochem Pharmacol 1991;42:1849-1857.
32. Korth HG, Sustmann R, Thater C, et al. On the mechanism of the nitric oxide synthase-catalyzed conversion of N-hydroxy-L-arginine to citrulline and nitric oxide. J Biol Chem 1994;269:17776-17779.
33. Marietta MA. Nitric oxide synthase structure and mechanism. J Biol Chem 1993;268:12231-12234.
34. Leone AM, Palmer RMJ, Knowles RG, et al. Constitutive and inducible nitric oxide synthases incorporate molecular oxygen into both nitric oxide and citrulline. J Biol Chem 1991;266:23790-23795.
35. Beckman JS, Conger KA. Direct measurement of dilute nitric oxide in solution with an ozone chemiluminescent detector. Methods Enzymol 1995;7:35-39.
36. Azuma H, Ishikawa M, Sekizaki S. Endothelium-dependent inhibition of platelet aggregation. Br J Pharmacol 1986;88:411-415.
37. Vanhoutte PM, Shimokawa H. Endothelium-derived relaxing factor and coronary vasospasm. Circulation 1989;80:1-9.
38. Fleming I, Busse R. Control and consequences of endothelial nitric oxide formation. Adv Pharmacol 1995;34:187-206.
39. Liu SF, Crawley DE, Barnes PJ, et al. Endothelium-derived nitric oxide inhibits pulmonary vasoconstriction in isolated perfused rat lungs. Am J Respir Rev 1991;143:32-37.
40. Ignarro LJ. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ Res 1989;65:1-21.
41. Marin J, Sanchez-Ferrer CF. Role of endothelium-formed nitric oxide on vascular responses. Gen Pharmacol 1990;21:575-587.
42. MacMicking JF, Nathan C, Hom G, et al. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 1995;82:641-650.
43. Stark ME, Szurszewski JH. Role of nitric oxide in gastrointestinal and hepatic function and disease. Gastroenterology 1992; 103:1928-1949.
44. Bone HG, Waurick R, Van Aken H, et al. Comparison of the haemodynamic effects of nitric oxide synthase inhibition and nitric oxide scavenging in endotoxaemic sheep. Intensive Care Med 1998;24:48-54.
45. Casadevall M, Pique JM, Cirera I, et al. Increased blood hemoglobin attenuates splanchnic vasodilation in portal-hypertensive rats by nitric oxide. Gastroenterology 1996;110:1156-1165.