메뉴 건너뛰기




Volumn 22, Issue 9, 2000, Pages 673-684

Hydroxyzine inhibits experimental allergic encephalomyelitis (EAE) and associated brain mast cell activation

Author keywords

Brain; Demyelination; Encephalomyelitis; Hydroxyzine; Inflammation; Mast cells; Multiple sclerosis; Secretion

Indexed keywords

HYDROXYZINE;

EID: 0034286991     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0192-0561(00)00029-1     Document Type: Article
Times cited : (78)

References (85)
  • 1
    • 0028157044 scopus 로고
    • Pathogenesis of multiple sclerosis
    • Ffrench-Constant C. Pathogenesis of multiple sclerosis. Lancet. 343:1994;271-279.
    • (1994) Lancet , vol.343 , pp. 271-279
    • Ffrench-Constant, C.1
  • 2
    • 0029052828 scopus 로고
    • The relationship between human multiple sclerosis and rodent experimental allergic encephalomyelitis
    • Heber-Katz E. The relationship between human multiple sclerosis and rodent experimental allergic encephalomyelitis. Ann. NY. Acad. Sci. 756:1995;283-293.
    • (1995) Ann. NY. Acad. Sci. , vol.756 , pp. 283-293
    • Heber-Katz, E.1
  • 3
    • 0021592979 scopus 로고
    • Analysis of autoimmune demyelination: Its impact upon multiple sclerosis
    • Raine C.S. Analysis of autoimmune demyelination: Its impact upon multiple sclerosis. Lab. Invest. 50:1984;608-635.
    • (1984) Lab. Invest. , vol.50 , pp. 608-635
    • Raine, C.S.1
  • 4
    • 0024236252 scopus 로고
    • Presence and distribution of nervous system-associated mast cells that may modulate experimental autoimmune encephalomyelitis
    • Orr E.L. Presence and distribution of nervous system-associated mast cells that may modulate experimental autoimmune encephalomyelitis. Ann. NY Acad. Sci. 540:1988;723-726.
    • (1988) Ann. NY Acad. Sci. , vol.540 , pp. 723-726
    • Orr, E.L.1
  • 5
    • 0026010153 scopus 로고
    • Mast cells in brains during experimental allergic encephalomyelitis in Lewis rats
    • Bo L., Olsson T., Nyland H., Kruger P.G., Taule A., Mork S. Mast cells in brains during experimental allergic encephalomyelitis in Lewis rats. J. Neurol. Sci. 105:(2):1991;135-142.
    • (1991) J. Neurol. Sci. , vol.105 , Issue.2 , pp. 135-142
    • Bo, L.1    Olsson, T.2    Nyland, H.3    Kruger, P.G.4    Taule, A.5    Mork, S.6
  • 6
    • 0016140137 scopus 로고
    • Mast cells in plaques of multiple sclerosis
    • Olsson Y. Mast cells in plaques of multiple sclerosis. Acta. Neurol. Scand. 50:1974;611-618.
    • (1974) Acta. Neurol. Scand. , vol.50 , pp. 611-618
    • Olsson, Y.1
  • 7
    • 0025161912 scopus 로고
    • Mast cells and multiple sclerosis: A light and electron microscopic study of mast cells in multiple sclerosis emphasizing staining procedures
    • Krüger P.G., Bo L., Myhr K.M., Karlsen A.E., Taule A., Nyland H.I., Mork S. Mast cells and multiple sclerosis: a light and electron microscopic study of mast cells in multiple sclerosis emphasizing staining procedures. Acta. Neurol. Scand. 81:1990;31-36.
    • (1990) Acta. Neurol. Scand. , vol.81 , pp. 31-36
    • Krüger, P.G.1    Bo, L.2    Myhr, K.M.3    Karlsen, A.E.4    Taule, A.5    Nyland, H.I.6    Mork, S.7
  • 9
    • 0025107628 scopus 로고
    • Identification of IgE-positive cells and mast cells in frozen sections of multiple sclerosis brains
    • Toms R., Weiner H.L., Johnson D. Identification of IgE-positive cells and mast cells in frozen sections of multiple sclerosis brains. J. Neuroimmunol. 30:1990;169-177.
    • (1990) J. Neuroimmunol. , vol.30 , pp. 169-177
    • Toms, R.1    Weiner, H.L.2    Johnson, D.3
  • 13
    • 0025734980 scopus 로고
    • Mast cell proteases liberate encephalitogenic fragments from intact myelin
    • Dietsch G.N., Hinrichs D.J. Mast cell proteases liberate encephalitogenic fragments from intact myelin. Cell Immunol. 135:1991;541-548.
    • (1991) Cell Immunol. , vol.135 , pp. 541-548
    • Dietsch, G.N.1    Hinrichs, D.J.2
  • 14
    • 0027433602 scopus 로고
    • Synergistic action of estradiol and myelin basic protein on mast cell secretion and brain demyelination: Changes resembling early stages of demyelination
    • Theoharides T.C., Dimitriadou V., Letourneau R.J., Rozniecki J.J., Vliagoftis H., Boucher W.S. Synergistic action of estradiol and myelin basic protein on mast cell secretion and brain demyelination: changes resembling early stages of demyelination. Neuroscience. 57:1993;861-871.
    • (1993) Neuroscience , vol.57 , pp. 861-871
    • Theoharides, T.C.1    Dimitriadou, V.2    Letourneau, R.J.3    Rozniecki, J.J.4    Vliagoftis, H.5    Boucher, W.S.6
  • 15
    • 0030024349 scopus 로고    scopus 로고
    • Identification of a committed precursor for the mast cell lineage
    • Rodewald H.-R., Dessing M., Dvorak A.M., Galli S.J. Identification of a committed precursor for the mast cell lineage. Science. 271:1996;818-822.
    • (1996) Science , vol.271 , pp. 818-822
    • Rodewald, H.-R.1    Dessing, M.2    Dvorak, A.M.3    Galli, S.J.4
  • 16
    • 0027925168 scopus 로고
    • New concepts about the mast cell
    • Galli S.J. New concepts about the mast cell. N. Engl. J. Med. 328:1993;257-265.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 257-265
    • Galli, S.J.1
  • 17
    • 0029738575 scopus 로고    scopus 로고
    • Mast cell: A neuroimmunoendocrine master player
    • Theoharides T.C. Mast cell: a neuroimmunoendocrine master player. Int. J. Tissue React. 18:1996;1-21.
    • (1996) Int. J. Tissue React. , vol.18 , pp. 1-21
    • Theoharides, T.C.1
  • 19
    • 0025248392 scopus 로고
    • Histochemical and ultrastructural characteristics of rat brain perivascular mast cells stimulated with compound 48/80 and carbachol
    • Dimitriadou V., Lambracht-Hall M., Reichler J., Theoharides T.C. Histochemical and ultrastructural characteristics of rat brain perivascular mast cells stimulated with compound 48/80 and carbachol. Neuroscience. 39:1990;209-224.
    • (1990) Neuroscience , vol.39 , pp. 209-224
    • Dimitriadou, V.1    Lambracht-Hall, M.2    Reichler, J.3    Theoharides, T.C.4
  • 20
    • 0017120460 scopus 로고
    • Mast cells in the mammalian brain. Part I. Distribution
    • Dropp J.J. Mast cells in the mammalian brain. Part I. Distribution. Acta. Anat. 94:1976;1-21.
    • (1976) Acta. Anat. , vol.94 , pp. 1-21
    • Dropp, J.J.1
  • 21
    • 0017662771 scopus 로고
    • Regional distribution of mast cells containing histamine, dopamine or 5-hydroxytryptamine in the mammalian brain
    • Edvinsson L., Cervos-Navarro J., Larsson L.I., Owman C., Ronnberg A.L. Regional distribution of mast cells containing histamine, dopamine or 5-hydroxytryptamine in the mammalian brain. Neurology. 27:1977;878-884.
    • (1977) Neurology , vol.27 , pp. 878-884
    • Edvinsson, L.1    Cervos-Navarro, J.2    Larsson, L.I.3    Owman, C.4    Ronnberg, A.L.5
  • 22
    • 0018593863 scopus 로고
    • Mast cells in the human brain
    • Dropp J.J. Mast cells in the human brain. Acta. Anat. 105:1979;505-513.
    • (1979) Acta. Anat. , vol.105 , pp. 505-513
    • Dropp, J.J.1
  • 23
    • 0018351694 scopus 로고
    • The mast cells of the mammalian central nervous system. Part III. Ultrastructural characteristics in the adult rat brain
    • Ibrahim M.Z., Al-Wirr M.E., Bahuth N. The mast cells of the mammalian central nervous system. Part III. Ultrastructural characteristics in the adult rat brain. Acta. Anat. 104:1979;134-154.
    • (1979) Acta. Anat. , vol.104 , pp. 134-154
    • Ibrahim, M.Z.1    Al-Wirr, M.E.2    Bahuth, N.3
  • 24
    • 0014381349 scopus 로고
    • Mast cells in the nervous system
    • Olsson Y. Mast cells in the nervous system. Int. Rev. Cytol. 24:1968;27-70.
    • (1968) Int. Rev. Cytol. , vol.24 , pp. 27-70
    • Olsson, Y.1
  • 25
    • 0016381057 scopus 로고
    • The mast cells of the mammalian central nervous system. Part I. Morphology, distribution and histochemistry
    • Ibrahim M.Z. The mast cells of the mammalian central nervous system. Part I. Morphology, distribution and histochemistry. J. Neurol. Sci. 21:1974;431-478.
    • (1974) J. Neurol. Sci. , vol.21 , pp. 431-478
    • Ibrahim, M.Z.1
  • 28
    • 0023194302 scopus 로고
    • Ultrastructural evidence for a functional unit between nerve fibers and type II cerebral mast cells in the cerebral vascular wall
    • Dimitriadou V., Aubineau P., Taxi J., Seylaz J. Ultrastructural evidence for a functional unit between nerve fibers and type II cerebral mast cells in the cerebral vascular wall. Neuroscience. 22:1987;621-630.
    • (1987) Neuroscience , vol.22 , pp. 621-630
    • Dimitriadou, V.1    Aubineau, P.2    Taxi, J.3    Seylaz, J.4
  • 29
    • 0026351110 scopus 로고
    • Influence of the sympathetic nervous system as well as trigeminal sensory fibres on rat dural mast cells
    • Keller J.T., Dimlich R.V., Zuccarello M., Lanker L., Strauss T.A., Fritts M.J. Influence of the sympathetic nervous system as well as trigeminal sensory fibres on rat dural mast cells. Cephalalgia. 11:(5):1991;215-221.
    • (1991) Cephalalgia , vol.11 , Issue.5 , pp. 215-221
    • Keller, J.T.1    Dimlich, R.V.2    Zuccarello, M.3    Lanker, L.4    Strauss, T.A.5    Fritts, M.J.6
  • 30
    • 0026505310 scopus 로고
    • Ultrastructural evidence for neurogenically mediated changes in blood vessels of the rat dura mater and tongue following antidromic trigeminal stimulation
    • Dimitriadou V., Buzzi M.G., Theoharides T.C., Moskowitz M.A. Ultrastructural evidence for neurogenically mediated changes in blood vessels of the rat dura mater and tongue following antidromic trigeminal stimulation. Neuroscience. 48:1992;187-203.
    • (1992) Neuroscience , vol.48 , pp. 187-203
    • Dimitriadou, V.1    Buzzi, M.G.2    Theoharides, T.C.3    Moskowitz, M.A.4
  • 31
    • 0025055444 scopus 로고
    • Mast cells: The immune gate to the brain
    • Theoharides T.C. Mast cells: the immune gate to the brain. Life Sci. 46:1990;607-617.
    • (1990) Life Sci. , vol.46 , pp. 607-617
    • Theoharides, T.C.1
  • 32
    • 0020446988 scopus 로고
    • Acute experimental autoimmune encephalomyelitis in mice
    • Linthicum D.S., Munoz J.J., Blaskett A. Acute experimental autoimmune encephalomyelitis in mice. Cell Immunol. 73:1982;299-310.
    • (1982) Cell Immunol. , vol.73 , pp. 299-310
    • Linthicum, D.S.1    Munoz, J.J.2    Blaskett, A.3
  • 33
    • 0029828329 scopus 로고    scopus 로고
    • Brain mast cell degranulation regulates blood-brain barrier
    • Zhuang X., Silverman A.-J., Silver R. Brain mast cell degranulation regulates blood-brain barrier. J. Neurobiol. 31:1996;393-403.
    • (1996) J. Neurobiol. , vol.31 , pp. 393-403
    • Zhuang, X.1    Silverman, A.-J.2    Silver, R.3
  • 35
    • 0029011440 scopus 로고
    • Blood-brain barrier disruption on contrast-enhanced MRI in patients with mild relapsing-remitting multiple sclerosis: Relationship to course, gender, and age
    • Stone L.A., Smith M.E., Albert P.S., Bash C.N., Maloni H., Frank J.A., McFarland H.F. Blood-brain barrier disruption on contrast-enhanced MRI in patients with mild relapsing-remitting multiple sclerosis: relationship to course, gender, and age. Neurology. 45:1995;1122-1126.
    • (1995) Neurology , vol.45 , pp. 1122-1126
    • Stone, L.A.1    Smith, M.E.2    Albert, P.S.3    Bash, C.N.4    Maloni, H.5    Frank, J.A.6    McFarland, H.F.7
  • 38
    • 0003021132 scopus 로고
    • Delayed-type hypersensitivity: Activation of mast cells by antigen-specific T-cell factors initiates the cascade of cellular interactions
    • Askenase P.W., Van Loveren H. Delayed-type hypersensitivity: activation of mast cells by antigen-specific T-cell factors initiates the cascade of cellular interactions. Immunol. Today. 4:1983;259-264.
    • (1983) Immunol. Today , vol.4 , pp. 259-264
    • Askenase, P.W.1    Van Loveren, H.2
  • 40
    • 0021846449 scopus 로고
    • Differential release of serotonin without comparable histamine under diverse conditions in the rat mast cell
    • Theoharides T.C., Kops S.K., Bondy P.K., Askenase P.W. Differential release of serotonin without comparable histamine under diverse conditions in the rat mast cell. Biochem. Pharmacol. 34:1985;1389-1398.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 1389-1398
    • Theoharides, T.C.1    Kops, S.K.2    Bondy, P.K.3    Askenase, P.W.4
  • 41
    • 0021829482 scopus 로고
    • Inhibitory effect of hydroxyzine on antigen induced histamine release in vivo
    • Ting S., Rauls D.O., Reimann B.E. Inhibitory effect of hydroxyzine on antigen induced histamine release in vivo. J. Allergy Clin. Immunol. 75:1985;63-66.
    • (1985) J. Allergy Clin. Immunol. , vol.75 , pp. 63-66
    • Ting, S.1    Rauls, D.O.2    Reimann, B.E.3
  • 44
    • 0025045751 scopus 로고
    • Attenuation of experimental autoimmune encephalomyelitis by compound 48/80 in Lewis rats
    • Stanley N.C., Jackson F.L., Orr E.L. Attenuation of experimental autoimmune encephalomyelitis by compound 48/80 in Lewis rats. J. Neuroimmunol. 29:1990;223-228.
    • (1990) J. Neuroimmunol. , vol.29 , pp. 223-228
    • Stanley, N.C.1    Jackson, F.L.2    Orr, E.L.3
  • 45
    • 0028221619 scopus 로고
    • Mast cells in experimental allergic encephalomyelitis: Characterization, distribution in the CNS and in vitro activation by myelin basic protein and neuropeptides
    • Brenner T., Soffer D., Shalit M., Levi-Schaffer F. Mast cells in experimental allergic encephalomyelitis: characterization, distribution in the CNS and in vitro activation by myelin basic protein and neuropeptides. J. Neurol. Sci. 122:1994;210-213.
    • (1994) J. Neurol. Sci. , vol.122 , pp. 210-213
    • Brenner, T.1    Soffer, D.2    Shalit, M.3    Levi-Schaffer, F.4
  • 46
    • 0025633516 scopus 로고
    • Dermal mast cell degranulation in systemic sclerosis
    • Seibold J.R., Giorno R.C., Claman H.N. Dermal mast cell degranulation in systemic sclerosis. Arthritis Rheum. 33:1990;1702-1709.
    • (1990) Arthritis Rheum. , vol.33 , pp. 1702-1709
    • Seibold, J.R.1    Giorno, R.C.2    Claman, H.N.3
  • 48
    • 0028029985 scopus 로고
    • Stem cell factor is a chemotactic factor for human mast cells
    • Nilsson G., Butterfield J.H., Nilsson K., Siegbahn A. Stem cell factor is a chemotactic factor for human mast cells. J. Immunol. 153:1994;3717-3723.
    • (1994) J. Immunol. , vol.153 , pp. 3717-3723
    • Nilsson, G.1    Butterfield, J.H.2    Nilsson, K.3    Siegbahn, A.4
  • 50
    • 0020062057 scopus 로고
    • Chronologic neuropathy of relapsing experimental allergic encephalomyelitis in the mouse
    • Brown A., McFarlin D.E., Raine C.S. Chronologic neuropathy of relapsing experimental allergic encephalomyelitis in the mouse. Lab Invest. 46:1982;171-185.
    • (1982) Lab Invest. , vol.46 , pp. 171-185
    • Brown, A.1    McFarlin, D.E.2    Raine, C.S.3
  • 51
    • 0021647175 scopus 로고
    • Experimental autoimmune demyelination chronic relapsing models and therapeutic implications for multiple sclerosis
    • Raine C.S., Traugott U. Experimental autoimmune demyelination chronic relapsing models and therapeutic implications for multiple sclerosis. Ann. NY Acad. Sci. 436:1984;33-51.
    • (1984) Ann. NY Acad. Sci. , vol.436 , pp. 33-51
    • Raine, C.S.1    Traugott, U.2
  • 52
    • 0017669366 scopus 로고
    • Mast cells increase in tissues of neonatal rats injected with the nerve growth factor
    • Aloe L., Levi-Montalcini R. Mast cells increase in tissues of neonatal rats injected with the nerve growth factor. Brain Res. 133:1977;358-366.
    • (1977) Brain Res. , vol.133 , pp. 358-366
    • Aloe, L.1    Levi-Montalcini, R.2
  • 54
    • 0022499601 scopus 로고
    • Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels
    • Mazurek N., Weskamp G., Ernst P., Otten U. Nerve growth factor induces mast cell degranulation without changing intracellular calcium levels. FEBS Lett. 198:1986;315-320.
    • (1986) FEBS Lett. , vol.198 , pp. 315-320
    • Mazurek, N.1    Weskamp, G.2    Ernst, P.3    Otten, U.4
  • 59
    • 24544455593 scopus 로고    scopus 로고
    • Acute psychological stress induces mast cell dependent increase in brain vascular permeability: Implications for multiple sclerosis (MS)
    • Abstract
    • Esposito P., Pang X., Boucher W. Acute psychological stress induces mast cell dependent increase in brain vascular permeability: implications for multiple sclerosis (MS). FASEB J. 13:1998;A326. Abstract.
    • (1998) FASEB J. , vol.13 , pp. 326
    • Esposito, P.1    Pang, X.2    Boucher, W.3
  • 60
    • 0342938625 scopus 로고    scopus 로고
    • An association between stress and development of new lesions in the brain and spinal cord of individuals with MS
    • Abstract
    • Morh D.E. An association between stress and development of new lesions in the brain and spinal cord of individuals with MS. Proc. Ann. Mtg. Soc. Beh. Medicine :1998;. Abstract.
    • (1998) Proc. Ann. Mtg. Soc. Beh. Medicine
    • Morh, D.E.1
  • 61
    • 0023257625 scopus 로고
    • Mediators of immediate hypersensitivity reactions
    • Serafin W.E., Austen K.F. Mediators of immediate hypersensitivity reactions. N. Engl. J. Med. 317:1987;30-34.
    • (1987) N. Engl. J. Med. , vol.317 , pp. 30-34
    • Serafin, W.E.1    Austen, K.F.2
  • 62
    • 0023219197 scopus 로고
    • Leakeness of rat brain microvessels to fluorescent probes following craniotomy
    • Olesen S.P. Leakeness of rat brain microvessels to fluorescent probes following craniotomy. Acta. Physiol. Scand. 130:1987;63-68.
    • (1987) Acta. Physiol. Scand. , vol.130 , pp. 63-68
    • Olesen, S.P.1
  • 63
    • 0023190708 scopus 로고
    • Permeability and vasomotor response of cerebral vessels during exposure to arachidonic acid
    • Unterberg A., Wahl M., Hammersen F., Baethmann A. Permeability and vasomotor response of cerebral vessels during exposure to arachidonic acid. Acta. Neuropathol. 73:1987;209-219.
    • (1987) Acta. Neuropathol. , vol.73 , pp. 209-219
    • Unterberg, A.1    Wahl, M.2    Hammersen, F.3    Baethmann, A.4
  • 64
    • 0024562724 scopus 로고
    • Blood-brain barrier permeability and vascular reactivity to bradykinin after pretreatment with dexamethasone
    • Schurer L., Temesvari P., Wahl M., Unterberg A., Baethmann A. Blood-brain barrier permeability and vascular reactivity to bradykinin after pretreatment with dexamethasone. Acta. Neuropathol. 77:1989;576-581.
    • (1989) Acta. Neuropathol. , vol.77 , pp. 576-581
    • Schurer, L.1    Temesvari, P.2    Wahl, M.3    Unterberg, A.4    Baethmann, A.5
  • 65
    • 0025312991 scopus 로고
    • Changes in blood-brain barrier and cerebral blood flow following elevation of circulating serotonin level in anesthetized rats
    • Sharma H.S., Olsson Y., Dey P.K. Changes in blood-brain barrier and cerebral blood flow following elevation of circulating serotonin level in anesthetized rats. Brain Res. 517:1990;215-223.
    • (1990) Brain Res. , vol.517 , pp. 215-223
    • Sharma, H.S.1    Olsson, Y.2    Dey, P.K.3
  • 66
    • 0025242472 scopus 로고
    • Mast cells as a source of multifunctional cytokines
    • Gordon J.R., Burd P.R., Galli S.J. Mast cells as a source of multifunctional cytokines. Immunol. Today. 11:1990;458-464.
    • (1990) Immunol. Today , vol.11 , pp. 458-464
    • Gordon, J.R.1    Burd, P.R.2    Galli, S.J.3
  • 67
    • 0025865284 scopus 로고
    • Human dermal mast cells contain and release tumor necrosis factor α, which induces endothelial leukocyte adhesion molecule 1
    • Walsh L.J., Trinchieri G., Waldorf H.A., Whitaker D., Murphy G.F. Human dermal mast cells contain and release tumor necrosis factor α, which induces endothelial leukocyte adhesion molecule 1. Proc. Natl. Acad. Sci., U.S.A. 88:1991;4220-4224.
    • (1991) Proc. Natl. Acad. Sci., U.S.A. , vol.88 , pp. 4220-4224
    • Walsh, L.J.1    Trinchieri, G.2    Waldorf, H.A.3    Whitaker, D.4    Murphy, G.F.5
  • 68
    • 0032484638 scopus 로고    scopus 로고
    • Evidence that brain mast cells can modulate neuroinflammatory responses by tumor necrosis factor-α production
    • Cocchiara R., Bongiovanni A., Albeggiani G., Azzolina A., Geraci D. Evidence that brain mast cells can modulate neuroinflammatory responses by tumor necrosis factor-α production. Neuroreport. 9:1998;95-98.
    • (1998) Neuroreport , vol.9 , pp. 95-98
    • Cocchiara, R.1    Bongiovanni, A.2    Albeggiani, G.3    Azzolina, A.4    Geraci, D.5
  • 71
    • 0027751693 scopus 로고
    • Increased levels of intercellular adhesion molecule-1 (ICAM-1) and tumor necrosis factor receptor in the cerebrospinal fluid of patients with multiple sclerosis
    • Tsukada N., Matsuda M., Miyagi K., Yanagisawa N. Increased levels of intercellular adhesion molecule-1 (ICAM-1) and tumor necrosis factor receptor in the cerebrospinal fluid of patients with multiple sclerosis. Neurology. 43:1993;2679-2682.
    • (1993) Neurology , vol.43 , pp. 2679-2682
    • Tsukada, N.1    Matsuda, M.2    Miyagi, K.3    Yanagisawa, N.4
  • 72
    • 0027409052 scopus 로고
    • Increased levels of circulating ICAM-1 in serum and cerebrospinal fluid of patients with active multiple sclerosis. Correlation with TNF-α And blood-brain barrier damage
    • Sharief M.K., Noori M.A., Ciardi M., Cirelli A., Thompson E.J. Increased levels of circulating ICAM-1 in serum and cerebrospinal fluid of patients with active multiple sclerosis. Correlation with TNF-α and blood-brain barrier damage. J. Neuroimmunol. 43:1993;15-22.
    • (1993) J. Neuroimmunol. , vol.43 , pp. 15-22
    • Sharief, M.K.1    Noori, M.A.2    Ciardi, M.3    Cirelli, A.4    Thompson, E.J.5
  • 73
    • 0027361834 scopus 로고
    • Soluble intercellular adhesion molecule-1 in cerebrospinal fluid: An indicator for the inflammatory impairment of the blood-cerebrospinal fluid barrier
    • Rieckmann P., Nünke K., Burchhardt M., Albrecht M., Wiltfang J., Ulrich M., Felgenhauer K. Soluble intercellular adhesion molecule-1 in cerebrospinal fluid: an indicator for the inflammatory impairment of the blood-cerebrospinal fluid barrier. J. Neuroimmunol. 47:1993;133-140.
    • (1993) J. Neuroimmunol. , vol.47 , pp. 133-140
    • Rieckmann, P.1    Nünke, K.2    Burchhardt, M.3    Albrecht, M.4    Wiltfang, J.5    Ulrich, M.6    Felgenhauer, K.7
  • 74
    • 0025165341 scopus 로고
    • Adhesion molecules on endothelial cells in the central nervous system: An emerging area in the neuroimmunology of multiple sclerosis
    • Raine C.S., Lee S.C., Scheinberg L.C., Duijvestijn A.M., Cross A.H. Adhesion molecules on endothelial cells in the central nervous system: an emerging area in the neuroimmunology of multiple sclerosis. Clin. Immunol. Immunopathol. 57:1990;173-187.
    • (1990) Clin. Immunol. Immunopathol. , vol.57 , pp. 173-187
    • Raine, C.S.1    Lee, S.C.2    Scheinberg, L.C.3    Duijvestijn, A.M.4    Cross, A.H.5
  • 75
    • 0025939412 scopus 로고
    • Relapsing autoimmune demyelination: A role for vascular addressins
    • Cannella B., Cross A.H., Raine C.S. Relapsing autoimmune demyelination: a role for vascular addressins. J. Neuroimmunol. 35:1991;295-300.
    • (1991) J. Neuroimmunol. , vol.35 , pp. 295-300
    • Cannella, B.1    Cross, A.H.2    Raine, C.S.3
  • 76
    • 0025168906 scopus 로고
    • Homing to central nervous system vasculature by antigen-specific lymphocytes. Part II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination
    • Raine C.S., Cannella B., Duijvestijn A.M., Cross A.H. Homing to central nervous system vasculature by antigen-specific lymphocytes. Part II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination. Lab. Invest. 63:1990;476-489.
    • (1990) Lab. Invest. , vol.63 , pp. 476-489
    • Raine, C.S.1    Cannella, B.2    Duijvestijn, A.M.3    Cross, A.H.4
  • 79
    • 0028819138 scopus 로고
    • The subarachnoid space as a site for precursor T cell proliferation and effector T cell selection in experimental autoimmune encephalomyelitis
    • Shin T., Kojima T., Tanuma N., Ishihara Y., Matsumoto Y. The subarachnoid space as a site for precursor T cell proliferation and effector T cell selection in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 56:1995;171-177.
    • (1995) J. Neuroimmunol. , vol.56 , pp. 171-177
    • Shin, T.1    Kojima, T.2    Tanuma, N.3    Ishihara, Y.4    Matsumoto, Y.5
  • 81
    • 0030827168 scopus 로고    scopus 로고
    • Perivascular T cells express the pro-inflammatory chemokine RANTES MRNA in multiple sclerosis lesions
    • Hvas J., McLean C., Justesen J., Kannourakis G., Steinman L., Oksenberg J.R. Perivascular T cells express the pro-inflammatory chemokine RANTES MRNA in multiple sclerosis lesions. Scand. J. Immunol. 46:1997;195-203.
    • (1997) Scand. J. Immunol. , vol.46 , pp. 195-203
    • Hvas, J.1    McLean, C.2    Justesen, J.3    Kannourakis, G.4    Steinman, L.5    Oksenberg, J.R.6
  • 83
    • 0024505050 scopus 로고
    • The role of mast cells in the elicitation of experimental allergic encephalomyelitis
    • Dietsch G.N., Hinrichs D.J. The role of mast cells in the elicitation of experimental allergic encephalomyelitis. J. Immunol. 142:1989;1476-1481.
    • (1989) J. Immunol. , vol.142 , pp. 1476-1481
    • Dietsch, G.N.1    Hinrichs, D.J.2
  • 84
  • 85
    • 0343809624 scopus 로고    scopus 로고
    • Acute psychological stress induces mast cell dependent increase in brain vascular permeability:implications for multiple sclerosis (MS) and inhibition by hydroxyzine
    • Abstract
    • Theoharides T.C., Esposito P., Pang X., et al. Acute psychological stress induces mast cell dependent increase in brain vascular permeability:implications for multiple sclerosis (MS) and inhibition by hydroxyzine. European Conference on Biomedical Research and Peace. 1999;58. Abstract.
    • (1999) European Conference on Biomedical Research and Peace , pp. 58
    • Theoharides, T.C.1    Esposito, P.2    Pang, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.