Prognostic significance of platelet and microvessel counts in operable non-small cell lung cancer

Lung Cancer

Volumn 29, Issue 3, 2000, Pages 169-177

  Cox, G ^a,b   Walker, R A ^b   Andi, A ^a   Steward, W P ^a   O'Byrne, K J ^a  

^a LEICESTER ROYAL INFIRMARY   (United Kingdom)

^b GLENFIELD HOSPITAL   (United Kingdom)

Author keywords

Angiogenesis; Non small cell lung cancer; Platelets

Indexed keywords

ANGIOGENIC FACTOR; BINDING PROTEIN; CD34 ANTIGEN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; BLOOD VESSEL PERMEABILITY; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROGNOSIS; THROMBOCYTE ADHESION; THROMBOCYTE COUNT;

ADULT; AGED; CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGE; NEOVASCULARIZATION, PATHOLOGIC; PLATELET ACTIVATION; PLATELET COUNT; PREGNANCY; PROGNOSIS; SURVIVAL ANALYSIS;

EID: 0034283301     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-5002(00)00124-0     Document Type: Article

References (30)

1. Folkman J. What is the evidence that tumors are angiogenesis-dependent? J. Natl. Cancer Inst. 82:1981;4-6.
2. Mountain C.F. Revisions in the international system for staging lung cancer. Chest. 111:1997;1711-1717.
3. Fontanini G., Vignati S., Bigini D., et al. Microvessel count predicts metastatic disease and overall survival in non-small-cell lung carcinomas. J. Pathol. 177:1995;57-63.
4. Giatromanolaki A., Koukourakis M., O'Byrne K., et al. Prognostic value of angiogenesis in operable non-small cell lung cancer. J. Pathol. 179:1996;80-88.
5. Fontanini G., Lucchi M., Vignati S., et al. Angiogenesis as a prospective indicator of survival in non-small-cell lung carcinoma: a prospective study. J. Natl. Cancer Inst. 89:1997;881-886.
6. Matsuyama K., Chiba Y., Sasaki M., Tanaka H., Muraoka R., Tanigawa N. Tumor angiogenesis as a prognostic marker in operable non-small cell lung cancer. Ann. Thorac. Surg. 65:1998;1405-1409.
7. Pastorino U., Andreola S., Tagliabue E., et al. Immunocytochemical markers in stage I lung cancer: relevance to prognosis. J. Clin. Oncol. 15:1997;2858-2865.
8. Chandrachud L.M., Pendleton N., Chisholm D.M., Horan M.A., Schor A.M. Relationship between vascularity, age and survival in non-small cell lung cancer. Br. J. Cancer. 76:1997;1367-1375.
9. Pedersen L.M., Milman N. Prognostic significance of thrombocytosis in patients with primary lung cancer. Eur. Resp. J. 9:1996;1826-1830.
10. Paesmans M., Sculier J.P., Libert P., et al. Prognostic factors for survival in advanced non-small-cell lung cancer: univariate and multivariate analyses including recursive and amalgamation algorithms in 1052 patients. The European Lung Cancer Working Party. J. Clin. Oncol. 13:1995;1221-1230.
11. Verheul H.M.W., Hoekman K., Luykx-de Bakker S., et al. Platelet: transporter of vascular endothelial growth factor. Clin. Cancer Res. 3:1997;2187-2190.
12. Mohle R., Green D., Moore M.A.S., Nachman R.L., Rafii S. Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proc. Natl. Acad. Sci. USA. 94:1997;663-668.
13. O'Byrne K.J., Dobbs N., Propper D., Smith K., Harris A.L. Vascular endothelial growth factor, platelet counts, and prognosis in renal cancer. Lancet. 353:1999;1494-1495.
14. Salgado R., Vermeulen P.B., Benoy I., et al. Platelet number and interleukin-6 correlate with VEGF but not bFGF serum levels of advanced cancer patients. Br. J. Cancer. 80:1999;892-897.
15. Dvorak H.F., Brown L.F., Detmar M., Dvorak A.M. Vascular permeability factor/vascular endothelial growth factor, microvascular permeability, and angiogenesis. Am. J. Pathol. 36:1995;139-155.
16. Pinedo H.M., Verheul H.M.W., D'Amato R.J., Folkman J. Involvement of platelets in tumour angiogenesis? Lancet. 352:1998;1775-1777.
17. World Health Organisation. The World Health Organisation histological typing of lung cancer. Am J Clin Pathol 1982;77:123-136.
18. Hollingsworth H.C., Kohn E.C., Steinberg S.M., Rothenberg M.L., Merino M.J. Tumor angiogenesis in advanced stage ovarian carcinoma. Am. J. Pathol. 147:1995;33-41.
19. Goulding H., Abdul Rashid N.F., Robertson J.F., et al. Assessment of angiogenesis in breast carcinoma: an important factor in prognosis? Hum. Pathol. 26:1995;1196-1200.
20. Weidner N., Semple J.P., Welch W.R., Folkman J. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N. Engl. J. Med. 324:1991;1-8.
21. Fox S.B., Leek R.D., Weekes M.P., Whitehouse R.M., Gatter K.C., Harris A.L. Quantification and prognostic value of breast cancer angiogenesis: comparison of microvessel density, Chalkley count, and computer image analysis. J. Pathol. 177:1995;275-283.
22. Imai T., Koike K., Kubo T., et al. Interleukin-6 supports human megakaryotype proliferation and differentiation in vitro. Blood. 78:1991;1959-1964.
23. Watson H.M., Sensintaffar J.L., Berek J.S., Martinez-Maza O. Constitutive production of interleukin-6 by ovarian cancer cell lines and by primary ovarian tumors. Cancer Res. 50:1990;6959-6965.
24. Yan S.F., Tritto I., Pinsky D., et al. Induction of interleukin 6 (IL-6) by hypoxia in vascular cells. J. Biol. Chem. 270:1995;11463-11471.
25. Brock T.A., Dvorak H.F., Senger D.R. Tumour secreted vascular permeability factor increases cytosolic Ca2+ and von Willebrand factor release in human endothelial cells. Am. J. Pathol. 138:1991;213-221.
26. Iruela-Arispe M.L., Bornstein P., Sage H. Thrombospondin exerts an antiangiogenic effect on tube formation by endothelial cells. Proc. Natl. Acad. Sci. USA. 88:1991;5026-5030.
27. Maione T.E., Gray G.S., Petro J., et al. Inhibition of angiogenesis by recombinant platelet factor-4 and related peptides. Science. 247:1990;77-79.
28. Fontanini G., Vignati S., Boldrini L., et al. Vascular endothelial growth factor is associated with neo-vascularization and infuences progression of non-small cell lung carcinoma. Clin. Cancer Res. 3:1997;861-865.
29. Tsao M.S., Liu N., Nicklee T., Shepherd F., Viallet J. Angiogenesis correlates with vascular endothelial growth factor expression but not with Ki-ras oncogene activation in non-small cell lung carcinoma. Clin. Cancer Res. 3:1997;1807-1814.
30. Koukourakis M.I., Giatromanolaki A., O'Byrne K.J., et al. Platelet-derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small-cell lung cancer. Br. J. Cancer. 75:1997;477-481.