Effect of low inoculation density in the scale-up of insect cell cultures

Biotechnology Progress

Volumn 16, Issue 5, 2000, Pages 795-799

  Marteijn, R C L ^a   Oude Elferink, M M A ^a   Martens, D E ^a   De Gooijer, C D ^a   Tramper, J ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOGRAPHA CALIFORNICA; BACULOVIRUS; INSECT CELL CULTURE; LOW INOCULATION DENSITY; VIRAL PASSAGE EFFECT;

CELL GROWTH; CELL LINE; INOCULATION; INSECT CELL CULTURE; SUSPENSION CELL CULTURE;

BIOREACTORS; CELLS; CONCENTRATION (PROCESS); GROWTH KINETICS; VIRUSES;

CELL CULTURE;

ANIMALS; BACULOVIRIDAE; CELL CULTURE TECHNIQUES; CELL DIVISION; SPODOPTERA;

AUTOGRAPHA CALIFORNICA; INSECTA; UNIDENTIFIED BACULOVIRUS;

EID: 0034281482     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp000104d     Document Type: Article

References (26)

1. Scale-up of insect cell cultures: Protective effects of Pluronic F-68
2. Lethal events during gas sparging animal cell culture
3. Cells and bubbles in sparged bioreactors
4. Analysis of cell-to-bubble attachment in sparged bioreactors in the presence of cell-protecting agents
5. Sparged animal cell bioreactors: Mechanism of cell damage and pluronic F-68 protection
6. Cell death from bursting bubbles: Role of cell attachment to rising bubbles in sparged reactors
7. Economics of baculovirus-insect cell production systems
8. Passage effect of virus infection in insect cells
9. Continuous production of baculovirus in a cascade of insect cell reactors
10. Longterm semi-continuous production of recombinant baculovirus protein in a repeated (fed-)batch two-stage reactor system
11. Baculoviruses
12. Detection and analysis of Autographa californica nuclear polyhedrosis virus mutants with defective interfering properties
13. Serial passage of a Helicoverpa armigera nucleopolyhedrovirus in Helicoverpa zea cell cultures
14. Factors influencing recombinant protein yields in an insect cell-baculovirus expression system: Multiplicity of infection and intracellular protein degradation
15. Modeling and optimization of the baculovirus expression vector system in batch suspension culture
16. Low multiplicity infection of insect cells with a recombinant baculo virus: The cell yield concept
17. Optimized production of recombinant bluetongue core-like particles produced by the baculovirus expression system
18. An insect baculovirus host-vector system for high-level expression of foreign genes
19. A manual of methods for baculovirus vectors and insect cell culture procedures
20. Growth limiting factors influencing high-density culture of insect cells in Grace's medium
21. Adaptation of insect cells to suspension culture
22. Suitability of the shaking flask for oxygen supply to microbiological cultures
23. Cell cycle model to describe animal cell size variation and lag between cell number and biomass dynamics
24. Cell volume measurement as an estimaion of mammalian cell biomass
25. Modeling of the bacterial growth curve