Why Lowering Blood Pressure is not Enough. The Hypertension Syndrome and the Clinical Context of Cardiovascular Risk Reduction

Heart Disease

Volumn 2, Issue 5, 2000, Pages 370-374

  Neutel, Joel M ^a  

^a Orange County Heart Institute and Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME INHIBITORS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; BLOOD PRESSURE; CARDIOVASCULAR DISEASE; DRUG EFFECT; HEALTH BEHAVIOR; HUMAN; HYPERTENSION; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; RISK FACTOR; SYNDROME;

ADULT; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; HEALTH BEHAVIOR; HUMAN; HYPERTENSION; RISK FACTORS; SUPPORT, NON-U.S. GOV'T; SYNDROME;

EID: 0034280366     PISSN: 1521737X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Grimm RH, Flack JM, Byington R, et al, the MIDAS Research Group. A comparison of antihypertensive drug effects on the progression of extracranial carotid atherosclerosis: the multicenter isradipine diuretic atherosclerosis study (MIDAS). Drugs 1900;40:38-42.
2. The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Arch Intern Med 1997;157: 2413-2446.
3. Havlik RJ, LaCroix AZ, Kleinman JC, et al. Antihypertensive drug therapy and survival by treatment status in a national survey. Hypertension 1989;13(Suppl I): 128-132.
4. American Heart Association. High blood pressure. Available at: http://www.americanheart.org/statistics/06hghbld.html. Accessed on May 24, 2000.
5. Samuelsson O, Wihelmsen L, Andersson OK, et al. Cardiovascular morbidity in relation to change in blood pressure and serum cholesterol levels in treated hypertension: results from the Primary Prevention Trial in Goteborg, Sweden. JAMA 1987;258:1768-1776.
6. Neutel JM, Smith DHG, Graettinger WF, et al. Heredity and hypertension: impact on metabolic characteristics. Am Heart J 1992;124:435-440.
7. Levy D, Garrison RJ, Savage DD, et al. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham heart study. N Engl J Med 1990;332:1561-1566.
8. Celentano A, Galderisi M, Garofalo M, et al. Blood pressure and cardiac morphology in young children of hypertensive subjects. J Hypertens 1988;6:S107-S109.
9. Taddei S, Virdis A, Mattei P, et al. Endothelium-dependent forearm vasodilation is reduced in normotensive subjects with familial history of hypertension. J Cardiovasc Pharmacol 1992;20(Suppl 12):S193-S195.
10. Swislocki ALM, Hoffman BB, Reaven GM. Insulin resistance, glucose intolerance, and hyperinsulinemia in patients with hypertension. Am J Hypertens 1989;2:419-423.
11. Neutel JM, Smith DHG, Graettinger WF, et al. Metabolic characteristics of hypertension: importance of positive family history. Am Heart J 1993;126:924-929.
12. Weber MA, Smith DHG, Neutel JM, et al. Arterial properties of early hypertension. J Hum Hypertens 1991;5:417-423.
13. Brunner HR, Laragh JH, Baer L. Essential hypertension: renin and aldosterone, heart attack and stroke. N Engl J Med 1972;286:441-449.
14. Clozel JP, Kuhn H, Hefti F. Decreases of vascular hypertrophy in four different types of arteries in spontaneously hypertensive rats. Am J Med 1989;87 (Suppl 6B): 92S-95S.
15. Sihm I, Schroeder AP, Aalkjer C, et al. Normalization of structural cardiovascular changes during antihypertensive treatment with a regimen based on the ACE-inhibitor perindopril. Blood Press 1995;4:241-248.
16. Asmar RG, Pannier B, Santoni JP, et al. Reversion of cardiac hypertrophy and reduced arterial compliance after converting enzyme inhibition in essential hypertension. Circulation 1988;78:941-950.
17. Thybo NK, Stephens N, Cooper A, et al. Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension. Hypertension 1995;25(Pt 1):474-481.
18. The Pooling Project Research Group. Relationship of blood pressure, serum cholesterol, smoking habit, relative weight and ECG abnormalities to incidence or major coronary events: final report of the pooling project. J Chron Dis 1978;31: 201-206.