Exposure to strong magnetic fields at power frequency potentiates X-ray-induced DNA strand breaks

Journal of Radiation Research

Volumn 41, Issue 3, 2000, Pages 293-302

  Miyakoshi, Junji ^a   Yoshida, Masami ^a   Shibuya, Keiko ^a   Hiraoka, Masahiro ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Alkaline comet assay; DNA strand breaks; MO54 cells; Power frequency magnetic field; X rays

Indexed keywords

CYTOLOGY; DNA; MAGNETIC FIELDS;

ALKALINE COMET ASSAY; CELL-BE; CELL/B.E; CELL/BE; DNA STRAND BREAK; EXPOSED TO; EXTREMELY LOW FREQUENCY MAGNETIC FIELDS; MO54 CELL; POWER FREQUENCY MAGNETIC FIELD; TAIL MOMENTS;

CELLS;

ARTICLE; CELL CULTURE; CELL DEATH; DNA DAMAGE; ELECTROMAGNETIC FIELD; HUMAN; RADIATION EXPOSURE; X RAY;

CELL DEATH; DNA DAMAGE; ELECTROMAGNETIC FIELDS; HUMANS; TUMOR CELLS, CULTURED; X-RAYS;

EID: 0034279590     PISSN: 04493060     EISSN: None     Source Type: Journal    
DOI: 10.1269/jrr.41.293     Document Type: Article

References (25)

1. Wertheimer, N. and Leeper, E. (1979) Electrical wiring configurations and child-hood cancer. Am. J. Epidemiol. 109: 273-284.
2. Savitz, D. A. and Loomis, D. P. (1995) Magnetic field exposure in relation to leukemia and brain cancer mortality among electric utility workers. Am. J. Epidemiol. 141: 123-134.
3. Linet, M. S., Hatch, E. E., Kleinerman, R. A., Robinson, L. L., Kaune, W. T., Friedman, D. R., Severson, R. K., Haines, C. M., Hartsock, C. T., Niwa, S., Wacholder, S. and Tarone, R. E. (1997) Residential exposure to magnetic fields and acute lymphoblastic leukemia in children. New Engl. J. Med. 337: 1-46.
4. Lai, H. and Singh, P. N. (1997) Acute exposure to a 60 Hz magnetic field increases DNA strand breaks in rat brain cells. Bioelectromagnetics 18: 156-165.
5. Narita, K., Hanakawa, K., Kasahara, T., Hisamitsu, T. and Asano, K. (1997) Induction of apoptotic cell death in human leukemic cell line, HL-60, by extremely low frequency electric magnetic fields: analysis of the possible mechanisms in vitro. In Vivo 11: 329-335.
6. Reese, J. A., Jostes, R. F. and Frazier, M. E. (1988) Exposure of mammalian cells to 60-Hz magnetic or electric fields: analysis for DNA single-strand breaks. Bioelectromagnetics 9: 237-247.
7. Frazier, M. E., Reese, J. A., Morris, J. E., Jostes, R. F. and Miller, D. L. (1990) Exposure of mammalian cells to 60-Hz magnetic or electric fields: analysis of DNA repair of induced, single-strand breaks. Bioelectromagnetics 11: 229-234.
8. Fairbairn, D. W. and O'Neill, K. L. (1994) The effect of electromagnetic field exposure on the formation of DNA single strand breaks in human cells. Cell. Mol. Biol. 40: 561-567.
9. Okuda, T., Nishizawa, K., Ejima, Y., Nakatsugawa, S., Ishigaki, T. and Ishizaki, K. (1998) The effects of static magnetic fields and X-rays on instability of microsatellite repetitive sequences. J. Radiat. Res. 39: 279-287
10. Miyakoshi, J., Ohtsu, S., Tatsumi-Miyajima, J. and Takebe, H. (1994) A newly designed experimental system for exposure of mammalian cells to extremely low frequency magnetic fields. J. Radiat. Res. 36: 26-34.
11. Yaguchi, H., Yoshida, M., Ejima, Y. and Miyakoshi, J. (1999) Effect of high-density extremely low frequency magnetic field on sister chromatid exchanges in mouse m5S cells. Mutat. Res. 440: 189-194.
12. Miyakoshi, J., Ohtsu, S., Shibata, T. and Takebe, H. (1996) Exposure to magnetic field (5 mT at 60 Hz) does not affect cell growth and c-myc gene expression. J. Radiat. Res. 37: 185-191.
13. Miyakoshi, J. and Yagi, K. (2000) Inhibition of I κ B-α phosphorylation at serine and tyrosine acts independently on sensitization to DNA damaging agents in human glioma cells. Br. J. Cancer. 82: 28-33.
14. Miyamae, J., Zaizen, K., Ohara, K., Mine, Y. and Sasaki Y. F. (1998) Detection of DNA lesions induced by chemical mutagens by the single cell gel electrophoresis (Comet) assay. 1. Relationship between the onset of DNA damage and the characteristics of mutagens. Mutat. Res. 415: 229-235.
15. Olive, P. L. and Banath, J. P. (1995) Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent. Exp. Cell Res. 221: 19-26.
16. Shibuya, K., Sasai, K., Xie, X., Utsumi, H., Shibata, T. and Hiraoka. M. (1999) Detection of hypoxic cells in murine tumors using the comet assay: comparison with a conventional radiobiological assay. Jpn. J. Cancer Res. 90: 880-886.
17. Lai, H. and Singh, N. P. (1997) Melatonin and N-tert-butyl-α-phenylnitrone block 60-Hz magnetic field-induced DNA single and double strand breaks in rat brain cells. J. Pineal Res. 22: 152-162.
18. Missakian, M. and Kaune, W. T. (1990) Optimal experimental design for in-vitro studies with ELF magnetic-fields. Bioelectromagnetics 11: 251-255.
19. Bassen, H., Litovitz, T., Penafiel, M. and Meister, R. (1992) ELF in vitro exposure systems for inducing uniform electric and magnetic fields in cell culture media. Bioelectromagnetics 13: 183-198.
20. Muller, W. U., Bauch, T., Streffer, C., Niedereichholz, F. and Bocker, W. (1994) Comet assay studies of radiation-induced DNA damage and repair in various tumour cell lines. Int. J. Radiat. Biol. 65: 315-319.
21. Cebulska-Wasilewska, A., Nowak, D., Niedzwiedz, W. and Anderson, D. (1998) Correlations between DNA and cytogenetic damage induced after chemical treatment and radiation. Mutat. Res. 421: 83-91.
22. Miyakoshi, J., Yamagishi, N., Ohtsu S., Mohri, K. and Takebe, H. (1996) Increase in hypoxanthine-guanine phosphoribosyl transferase gene mutations by exposure to high-density 50-Hz magnetic fields. Mutat. Res. 349: 109-114.
23. Miyakoshi, J., Kitagawa, K. and Takebe, H. (1997) Mutation induction by high-density, 50-Hz magnetic fields in human MeWo cells exposed in the DNA synthesis phase. Int. J. Radiat. Biol. 71: 75-79.
24. Miyakoshi, J., Koji, Y., Wakasa, T. and Takebe, H. (1999) Long-term exposure to a magnetic field (5 mT at 60 Hz) increases X-ray-induced mutations. J. Radiat. Res. 40: 13-21.
25. Walleczek, J., Shiu, E. C. and Hahn, G. M. (1999) Increase in radiation-induced HPRT gene mutation frequency after nonthermal exposure to nonionizing 60 Hz electromagnetic fields. Radiat. Res. 151: 489-497.