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Volumn 2, Issue 5, 2000, Pages 508-512

Solid phase synthesis of tertiary amines on amide REM resins: Grignard and metal hydride compatible resins

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; AMINE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; PLANT RESIN;

EID: 0034263268     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc000023+     Document Type: Article
Times cited : (16)

References (19)
  • 1
    • 0033156688 scopus 로고    scopus 로고
    • Comprehensive survey of combinatorial library synthesis 1998
    • Dolle, R. E.; Nelson, K. H. Comprehensive survey of combinatorial library synthesis 1998. J. Comb. Chem. 1999, 1, 235-282. Bunin, B. A.; Dener, J. M.; Livingstone, D. A. Application of combinatorial and parallel synthesis to medicinal chemistry. Ann. Rep. Med. Chem. 1999, 27, 267-286.
    • (1999) J. Comb. Chem. , vol.1 , pp. 235-282
    • Dolle, R.E.1    Nelson, K.H.2
  • 2
    • 77956769873 scopus 로고    scopus 로고
    • Application of combinatorial and parallel synthesis to medicinal chemistry
    • Dolle, R. E.; Nelson, K. H. Comprehensive survey of combinatorial library synthesis 1998. J. Comb. Chem. 1999, 1, 235-282. Bunin, B. A.; Dener, J. M.; Livingstone, D. A. Application of combinatorial and parallel synthesis to medicinal chemistry. Ann. Rep. Med. Chem. 1999, 27, 267-286.
    • (1999) Ann. Rep. Med. Chem. , vol.27 , pp. 267-286
    • Bunin, B.A.1    Dener, J.M.2    Livingstone, D.A.3
  • 3
    • 33751156625 scopus 로고
    • A silicon based linker for traceless solid phase synthesis
    • Plunkett, M. J.; Ellman, J. A. A silicon based linker for traceless solid phase synthesis. J. Org. Chem. 1995, 60, 6006-6007.
    • (1995) J. Org. Chem. , vol.60 , pp. 6006-6007
    • Plunkett, M.J.1    Ellman, J.A.2
  • 4
    • 0013249477 scopus 로고
    • Protodetachable arylsilane polymer linkages for use in solid phase organic synthesis
    • Chenera, B.; Finkelstein, J. A.: Veber, D. F. Protodetachable arylsilane polymer linkages for use in solid phase organic synthesis. J. Am. Chem. Soc. 1995, 117, 11999-12000.
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 11999-12000
    • Chenera, B.1    Finkelstein, J.A.2    Veber, D.F.3
  • 5
    • 0000576958 scopus 로고    scopus 로고
    • Development of a novel silyl ether linker for solid phase organic synthesis
    • Boehm, T.; Showalter, H. D. H. Development of a novel silyl ether linker for solid phase organic synthesis. J. Org. Chem. 1996, 61, 6498-6499.
    • (1996) J. Org. Chem. , vol.61 , pp. 6498-6499
    • Boehm, T.1    Showalter, H.D.H.2
  • 6
    • 0029991217 scopus 로고    scopus 로고
    • A novel linker strategy for solid phase synthesis
    • Morphy, J. R.; Rankovic, Z.; Rees, D. C. A novel linker strategy for solid phase synthesis. Tetrahedron Lett. 1996, 37, 3209-3212.
    • (1996) Tetrahedron Lett. , vol.37 , pp. 3209-3212
    • Morphy, J.R.1    Rankovic, Z.2    Rees, D.C.3
  • 7
    • 0030921936 scopus 로고    scopus 로고
    • Synthesis of tertiary amines using a polystyrene (REM) resin
    • Brown, A. R.; Rees, D. C.; Rankovic, Z.; Morphy, J. R. Synthesis of tertiary amines using a polystyrene (REM) resin. J. Am. Chem. Soc. 1997, 119, 3288-3295. Ouyang, X.; Armstrong, R. W.; Murphy, M. M. A novel cleavage technique to generate small molecule compounds and libraries via a two-resin system. J. Org. Chem. 1998, 63, 1027-1032.
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 3288-3295
    • Brown, A.R.1    Rees, D.C.2    Rankovic, Z.3    Morphy, J.R.4
  • 8
    • 0000140378 scopus 로고    scopus 로고
    • A novel cleavage technique to generate small molecule compounds and libraries via a two-resin system
    • Brown, A. R.; Rees, D. C.; Rankovic, Z.; Morphy, J. R. Synthesis of tertiary amines using a polystyrene (REM) resin. J. Am. Chem. Soc. 1997, 119, 3288-3295. Ouyang, X.; Armstrong, R. W.; Murphy, M. M. A novel cleavage technique to generate small molecule compounds and libraries via a two-resin system. J. Org. Chem. 1998, 63, 1027-1032.
    • (1998) J. Org. Chem. , vol.63 , pp. 1027-1032
    • Ouyang, X.1    Armstrong, R.W.2    Murphy, M.M.3
  • 9
    • 0030681297 scopus 로고    scopus 로고
    • Resin-immobilised benzyl and aryl vinyl sulphones: New versatile traceless linkers for solid phase organic synthesis
    • Kroll, F. E. K.; Morphy, R.; Rees, D.; Gani, D. Resin-immobilised benzyl and aryl vinyl sulphones: new versatile traceless linkers for solid phase organic synthesis. Tetrahedron Lett. 1997, 38, 8573-8576. Heinonen, P.; Lonnberg, H.; A novel solid support for derivatisation and subsequent N-alkylation of secondary amines: preparation of N-alkylated 5- and 6-alkoxy-1,2,3,4-tetrahydroisoquinolines via Mitsunobu reaction. Tetrahedron Lett. 1997, 38, 8569-8572.
    • (1997) Tetrahedron Lett. , vol.38 , pp. 8573-8576
    • Kroll, F.E.K.1    Morphy, R.2    Rees, D.3    Gani, D.4
  • 10
    • 0343307034 scopus 로고    scopus 로고
    • A novel solid support for derivatisation and subsequent N-alkylation of secondary amines: Preparation of N-alkylated 5- and 6-alkoxy-1,2,3,4-tetrahydroisoquinolines via mitsunobu reaction
    • Kroll, F. E. K.; Morphy, R.; Rees, D.; Gani, D. Resin-immobilised benzyl and aryl vinyl sulphones: new versatile traceless linkers for solid phase organic synthesis. Tetrahedron Lett. 1997, 38, 8573-8576. Heinonen, P.; Lonnberg, H.; A novel solid support for derivatisation and subsequent N-alkylation of secondary amines: preparation of N-alkylated 5- and 6-alkoxy-1,2,3,4-tetrahydroisoquinolines via Mitsunobu reaction. Tetrahedron Lett. 1997, 38, 8569-8572.
    • (1997) Tetrahedron Lett. , vol.38 , pp. 8569-8572
    • Heinonen, P.1    Lonnberg, H.2
  • 12
    • 0030605889 scopus 로고    scopus 로고
    • Aryl-aryl cross coupling on a solid support using zinc organic reagents and palladium catalysis
    • Marquais, S.; Arlt, M. Aryl-aryl cross coupling on a solid support using zinc organic reagents and palladium catalysis. Tetrahedron Lett. 1996, 37, 5491-5494.
    • (1996) Tetrahedron Lett. , vol.37 , pp. 5491-5494
    • Marquais, S.1    Arlt, M.2
  • 13
    • 0028088788 scopus 로고
    • Biaryl synthesis via Suzuki coupling on a solid support
    • Frenette, R.; Friesen, R. W. Biaryl synthesis via Suzuki coupling on a solid support. Tetrahedron Lett. 1994, 35, 9177-9180.
    • (1994) Tetrahedron Lett. , vol.35 , pp. 9177-9180
    • Frenette, R.1    Friesen, R.W.2
  • 14
    • 0010186303 scopus 로고
    • Comparative study of reactions of 2-benzylisoquinolinium and 3,4-dihydro-2-benzylisoquinolinium salts with carbon disulphide in two base-solvent environments
    • Duncan, J. A.; Bosse, M. L.; Masnovi, J. M. Comparative study of reactions of 2-benzylisoquinolinium and 3,4-dihydro-2-benzylisoquinolinium salts with carbon disulphide in two base-solvent environments. J. Org. Chem. 1980, 45, 3176-3181.
    • (1980) J. Org. Chem. , vol.45 , pp. 3176-3181
    • Duncan, J.A.1    Bosse, M.L.2    Masnovi, J.M.3
  • 15
    • 0042276344 scopus 로고
    • Parasympathetic blocking agents III. N-alkylpiperidine carboxylic esters
    • Sperber, N.; Sherlock, M.; Papa, D.; Kender, D. Parasympathetic blocking agents III. N-alkylpiperidine carboxylic esters. J. Am. Chem. Soc. 1959, 81, 704-709.
    • (1959) J. Am. Chem. Soc. , vol.81 , pp. 704-709
    • Sperber, N.1    Sherlock, M.2    Papa, D.3    Kender, D.4
  • 17
    • 0042777486 scopus 로고
    • Studies in the pyridine series XLIV. Synthesis of some 1-methyl-4-(hydroxyalkyl)piperidines
    • Ferles, M.; Stern, P.; Vysata, F. Studies in the pyridine series XLIV. Synthesis of some 1-methyl-4-(hydroxyalkyl)piperidines. Collect. Czech. Chem. Commun. 1973, 38, 1977-1980.
    • (1973) Collect. Czech. Chem. Commun. , vol.38 , pp. 1977-1980
    • Ferles, M.1    Stern, P.2    Vysata, F.3
  • 18
    • 0042276343 scopus 로고
    • Synthesis of α,α-diphenyl-4-piperidinemethanol(azacyclonol), an intermediate for terfenadine
    • Sathe, D. G.; Kulkarni, P. B.; Kulkarni, V. M. Synthesis of α,α-diphenyl-4-piperidinemethanol(azacyclonol), an intermediate for terfenadine. Ind. J. Chem. 1993, 32B, 475-476.
    • (1993) Ind. J. Chem. , vol.32 B , pp. 475-476
    • Sathe, D.G.1    Kulkarni, P.B.2    Kulkarni, V.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.