Synergy between combinatorial chemistry and de novo design

Journal of Molecular Graphics and Modelling

Volumn 18, Issue 4-5, 2000, Pages

  Leach, Andrew R ^a   Bryce, Richard A ^a   Robinson, Alan J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Combinatorial libraries; De novo design; Structure based design

Indexed keywords

CARBON; DATABASE SYSTEMS; DRUG THERAPY; MOLECULES; PHARMACODYNAMICS; PROTEINS; ALGORITHMS; COMBINATORIAL MATHEMATICS; CONFORMATIONS; CONSTRAINT THEORY;

COMBINATORIAL LIBRARY;

MOLECULAR GRAPHICS; MOLECULAR DYNAMICS;

FUNCTIONAL GROUP; REAGENT;

ALGORITHM; ARTICLE; CHEMICAL BOND; COMBINATORIAL CHEMISTRY; CONFORMATIONAL TRANSITION; DATA BASE; MOLECULAR INTERACTION; MOLECULAR MODEL; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ALGORITHMS; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTER GRAPHICS; COMPUTER SIMULATION; DRUG DESIGN; INDICATORS AND REAGENTS; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE;

COMBINATORIAL CHEMISTRY;

EID: 0034240696     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1093-3263(00)00062-0     Document Type: Article

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