(9-[4-acetyl-3-hydroxy-2-n-propylphenoxy) methyl]-3-(1H-tetrazol-5-yl)-4H-pyrido [1, 2-a] pyrimidin-4-one), AS-35, inhibits leukotriene synthesis

International Journal of Immunopharmacology

Volumn 22, Issue 7, 2000, Pages 483-490

  Hamasaki, Yuhei ^a   Zaitu, Masafumi ^a   Tsuji, Kosuke ^a   Miyazaki, Michiko ^a   Hayasaki, Rika ^a   Muro, Eriko ^a   Yamamoto, Shuichi ^a   Kobayashi, Ikuko ^a   Matsuo, Muneaki ^a   Ichimaru, Tomohiro ^a   Miyazaki, Sumio ^a  

^a SAGA UNIVERSITY   (Japan)

Author keywords

(9 4 acetyl 3 hydroxy 2 n propylphenoxy) methyl 3 (1H tetrazol 5 yl) 4H pyrido 1; 2 a pyrimidin 4 one); 5 lipoxygenase (5 LO); AS 35; cytosolic phospholipase A2 (cPLA2); LTA4 hydrolase; LTC4 synthase; rat basophilic leukemia (RBL) 2H3 cells

Indexed keywords

9 [(4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY)METHYL] 3 (1H TETRAZOL 5 YL) 4H PYRIDO[1,2 A]PYRIMIDIN 4 ONE; ANTIALLERGIC AGENT; ARACHIDONATE 5 LIPOXYGENASE; BETA N ACETYLHEXOSAMINIDASE B; CALCIMYCIN; IMMUNOGLOBULIN E; LEUKOTRIENE A4 HYDROLASE; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE C4 SYNTHASE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; PHOSPHOLIPASE A2;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; ENZYME ACTIVITY; IN VITRO STUDY; LEUKEMIA CELL LINE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ARACHIDONIC ACID; BETA-N-ACETYLHEXOSAMINIDASE; CELL-FREE SYSTEM; CYTOSOL; LEUKOTRIENE A4; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENE B4; LEUKOTRIENE C4; PHOSPHOLIPASES A; PYRIDINES; PYRIMIDINONES; RATS; SUBSTRATE SPECIFICITY; TETRAZOLES; TUMOR CELLS, CULTURED;

EID: 0034237645     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0192-0561(00)00010-2     Document Type: Article

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