A disease-associated glycine substitution in BP180 (type XVII collagen) leads to a local destabilization of the major collagen triple helix

Matrix Biology

Volumn 19, Issue 3, 2000, Pages 223-233

  Olague Marchan, Monica ^a   Twining, Sally S ^a   Hacker, Mary K ^a   McGrath, John A ^b   Diaz, Luis A ^a,c   Giudice, George J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Dental disease; Epidermolysis bullosa; Hemidesmosome

Indexed keywords

COLLAGEN TYPE 17; MEMBRANE PROTEIN; RECOMBINANT PROTEIN;

ARTICLE; EPIDERMOLYSIS BULLOSA; GENE CONSTRUCT; HUMAN; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; AUTOANTIGENS; CARRIER PROTEINS; CELL LINE, TRANSFORMED; COLLAGEN; CYTOSKELETAL PROTEINS; GENE EXPRESSION; GLYCINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; NON-FIBRILLAR COLLAGENS; RABBITS; RECOMBINANT FUSION PROTEINS; TRYPSIN;

EID: 0034233596     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0945-053X(00)00070-6     Document Type: Article

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