Synthesis, molecular modeling, and opioid receptor affinity of 9,10- diazatricyclo[4.2.1.12,5]decanes and 2,7- diazatricyclo[4.4.0.03,8]decanes structurally related to 3,8- diazabicyclo[3.2.1]octanes

Journal of Medicinal Chemistry

Volumn 43, Issue 11, 2000, Pages 2115-2123

  Vianello, Paola ^a,f   Albinati, Alberto ^a   Pinna, Gerardo A ^b   Lavecchia, Antonio ^c   Marinelli, Luciana ^c   Borea, Pier Andrea ^d   Gessi, Stefania ^d   Fadda, Paola ^e   Tronci, Silvia ^e   Cignarella, Giorgio ^a  

^a Istituto di Chimica Farmaceutica e Tossicologica   (Italy)

^b Dipartimento Farmaco Chimico Tossicologico   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY OF FERRARA   (Italy)

^e Dipartimento di Neuroscienze   (Italy)

^f PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 PROPIONYL 7 ARYLALKENYL 2,7 DIAZATRICYCLO[4.4.0.03,8]DECANE; 9 PROPIONYL 10 ARYLALKENYL 9,10 DIAZATRICYCLO[4.2.1.12,5] DECANE; DECANE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL TISSUE; ARTICLE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION;

EID: 0034214133     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991140q     Document Type: Article

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