Mathematical modeling of citric acid production by repeated batch culture

Enzyme and Microbial Technology

Volumn 26, Issue 9-10, 2000, Pages 826-833

  Arzumanov, Tigran E ^a   Sidorov, Igor A ^a,b   Shishkanova, Nadezhda V ^a   Finogenova, Tatyana V ^a  

^a SKRYABIN INSTITUTE OF BIOCHEMISTRY AND PHYSIOLOGY OF MICROORGANISMS   (Russian Federation)

^b PUSHCHINO STATE UNIVERSITY   (Russian Federation)

Author keywords

Citric acid; Modeling; Optimization; Repeated batch; Yarrowia lipolytica

Indexed keywords

ADDITION REACTIONS; BATCH CELL CULTURE; COMPOSITION; DIFFERENTIAL EQUATIONS; FERMENTATION; GROWTH KINETICS; MATHEMATICAL MODELS; NITROGEN; ORGANIC ACIDS; PH EFFECTS; SODIUM COMPOUNDS; YEAST;

CITRIC ACID; YARROWIA LIPOLYTICA;

BIOSYNTHESIS;

CITRIC ACID;

BIOMASS; BIOSYNTHESIS; CONFERENCE PAPER; FERMENTATION; FUNGUS GROWTH; MATHEMATICAL MODEL; NONHUMAN; NUTRIENT; YARROWIA LIPOLYTICA;

YARROWIA LIPOLYTICA;

EID: 0034213196     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(00)00178-2     Document Type: Conference Paper

References (20)

1. Kirk-Othmer. Encyclopedia of chemical technology. John Wiley & Sons, Inc. 1979. vol. 6, p. 150.
2. Milsom PE, Meers JL. Citric acid. In: M. Moo-Young, editor. Comprehensive Biotechnology 1985. p. 665-80.
3. de Hollander J.A. Application of a metabolic balancing technique to the analysis of microbial fermentation data. Antonie van Leeuwenhoek. 60:1991;275-292.
4. Klasson TK, Clausen EC, Gaddy JL. Continuous fermentation for the production of citric acid from glucose. Appl Biochem Biotechnol 1989;20/21:491-509.
5. Klasson K.T., Ackerson M.D., Clausen E.C., Gaddy J.L. Modeling lysine and citric acid production in terms of initial limiting nutrient concentrations. J Biotechnol. 21:1991;271-282.
6. Mori H., Yamane T., Kobayashi T., Shimizu S. Comparison of cell productivities among fed-batch, repeated fed-batch, and continuous cultures at high cell concentration. J Ferment Technol. 61:1983;391-401.
7. Weigand W.A. Maximum cell productivity by repeated fed-batch culture for constant yield case. Biotechnol Bioeng. 23:1981;249-266.
8. Guthke R., Knorre W.A. Efficiency of the cyclic batch antibiotic fermentation. Biotechnol Bioeng. 24:1982;2129-2136.
9. Arzumanov TE, Shishkanova NV, Finogenova TV. Biosynthesis of citric acid by Yarrowia lipolytica repeated batch culture on ethanol. Appl Microbiol Biotechnol 2000 (in print).
10. Burkholder P.R. Influence of some environmental factors upon the production of riboflavin by yeast. Arch Biochem. 3:1943;121-130.
11. Zhabolovskaya N.A., Ageev L.M., Petrova L.F. Sravnitelnaya ozenka metodov kolichestvennogo opredeleniya limonnoi kisloty. Khlebopekarnaya i konditer-skaya promyshlennost'. 5:1968;22-24. (in Russian).
12. Park Y.S., Toda K. Simulation study on bleed effect in cell-recycle culture of Acetobacter aceti. J Gen Appl Microbiol. 36:1990;221-233.
13. Goronovski IT, Nazarenko IP, Nekriatch EF. Kratkii spravochnik po khimii. Kiev: Naukova Dumka. (in Russian), 1987.
14. Marchuk G.I., Romanyukha A.A., Bocharov G.A. Mathematical model of antiviral immune response. II. Parameters identification for acute viral hepatitis B. J Theoret Biol. 151:1991;41-70.
15. James F., Roos M. MINUIT - A system for function minimization and analysis of the parameter errors and correlation. Comp Phys Commun. 10:1975;343-367.
16. Stanier R.Y., Doudoroff M., Edward A.A. The microbial world. 1970;Prentice-Hall, Englewood Cliffs, NJ.
17. Kamzolova S.V., Chistyakova T.I., Dedyuhina E.G., Shishkanova N.V., Finogenova T.V. Effects of temperature, pH, and ethanol concentration on the maximal specific growth rate and biomass composition of Yarrowia lipolytica, mutant strain no. 1. Microbiology. 65:1996;176-180.
18. Briffaud J., Engasser J. Citric acid production from glucose. I. Growth and excretion kinetics in a stirred fermentor. Biotechnol Bioeng. 21:1979;2083-2092.
19. Pirt S.J. Principles of microbe and cell cultivation. 1975;Blackwell Scientific Pub, London.
20. Wojtatowicz M., Rymowicz W. Effect of inoculum on kinetics and yield of citric acids production on glucose by Yarrowia lipolytica A-101. Acta Aliment Polon. 17:1991;137-143.