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1
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0027346972
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Myristoyl CoA:Protein N-myristoyltransferase
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1 Rudnick, D. A., McWherter, C. A., Gokel, G. W. and Gordon, J. I. (1993) Myristoyl CoA:protein N-myristoyltransferase. Adv. Enzymol. Relat. Areas Mol. Biol. 67, 375-430
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Rudnick, D.A.1
McWherter, C.A.2
Gokel, G.W.3
Gordon, J.I.4
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2
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0028000667
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Comparison of myristoyl-CoA:Protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans
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2 Lodge, J. K., Johnson, R. L., Weinberg, R. A. and Gordon, J. I. (1994) Comparison of myristoyl-CoA:protein N-myristoyltransferases from three pathogenic fungi: Cryptococcus neoformans, Histoplasma capsulatum, and Candida albicans. J. Biol. Chem. 269, 2996-3009
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Lodge, J.K.1
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Weinberg, R.A.3
Gordon, J.I.4
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3
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0028053746
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Targeted gene replacement demonstrates that myristoyl-CoA:Protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans
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3 Lodge, J. K., Jackson-Machelski, E., Toffaletti, D. L., Perfect, J. R. and Gordon, J. I. (1994) Targeted gene replacement demonstrates that myristoyl-CoA:protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans. Proc. Natl. Acad. Sci. U.S.A. 91, 12008-12012
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Lodge, J.K.1
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Toffaletti, D.L.3
Perfect, J.R.4
Gordon, J.I.5
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4
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0029070249
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Genetic studies reveal that myristoyl CoA:Protein N-myristoyltransferase is an essential enzyme in Candida albicans
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4 Weinberg, R. A., McWherter, C. A., Freeman, S. K., Wood, D. C., Gordon, J. I. and Lee, S. C. (1995) Genetic studies reveal that myristoyl CoA:protein N-myristoyltransferase is an essential enzyme in Candida albicans. Mol. Microbiol. 16, 241-250
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Weinberg, R.A.1
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Gordon, J.I.5
Lee, S.C.6
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5
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0024590280
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Disruption of the yeast N-myristoyl transferase gene causes recessive lethality
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5 Duronio, R. J., Towler, D. A., Heuckeroth, R. O. and Gordon, J. I. (1989) Disruption of the yeast N-myristoyl transferase gene causes recessive lethality. Science 243, 796-800
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Duronio, R.J.1
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6
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0026544934
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Mutations of human myristoyl-CoA:Protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae
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6 Duronio, R. J., Reed, S. I. and Gordon, J. I. (1992) Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 89, 4129-4133
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Duronio, R.J.1
Reed, S.I.2
Gordon, J.I.3
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7
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0027095974
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Studies of the catalytic activities and substrate specificities of Saccharomyces cerevisiae myristoyl-coenzyme A:Protein N-myristoyltransferase deletion mutants and human/yeast Nmt chimeras in Escherichia coli and S. cerevisiae
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7 Rudnick, D. A., Johnson, R. L. and Gordon, J. I. (1992) Studies of the catalytic activities and substrate specificities of Saccharomyces cerevisiae myristoyl-coenzyme A:protein N-myristoyltransferase deletion mutants and human/yeast Nmt chimeras in Escherichia coli and S. cerevisiae. J. Biol. Chem. 267, 23852-23861
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Rudnick, D.A.1
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Gordon, J.I.3
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8
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0023931431
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Myristoyl CoA:Protein N-myristoyltransferase activities from rat liver and yeast possess overlapping yet distinct peptide substrate specificities
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8 Towler, D. A., Adams, S. P., Eubanks, S. R., Towery, D. S., Jackson-Machelski, E., Glaser, L. and Gordon, J. I. (1988) Myristoyl CoA:protein N-myristoyltransferase activities from rat liver and yeast possess overlapping yet distinct peptide substrate specificities. J. Biol. Chem. 263, 1784-1790
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Towler, D.A.1
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Towery, D.S.4
Jackson-Machelski, E.5
Glaser, L.6
Gordon, J.I.7
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9
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15144355281
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Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoyl-CoA:Protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity
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9 Devadas, B., Freeman, S. K., Zupec, M. E., Lu, H. F., Nagarajan, S. R., Kishore, N. S., Lodge, J. K., Kuneman, D. W., McWherter, C. A., Vinjamoori, D. V. et al. (1997) Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoyl-CoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity. J. Med. Chem. 40, 2609-2625
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Devadas, B.1
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Kuneman, D.W.8
McWherter, C.A.9
Vinjamoori, D.V.10
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10
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0032510384
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Novel biologically active nonpeptidic inhibitors of myristoyl CoA:Protein N-myristoyltransferase
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10 Devadas, B., Freeman, S. K., McWherter, C. A., Kishore, N. S., Lodge, J. K., Jackson-Machelski, E., Gordon, J. I. and Sikorski, J. A. (1998) Novel biologically active nonpeptidic inhibitors of myristoyl CoA:protein N-myristoyltransferase. J. Med. Chem. 41, 996-1000
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Devadas, B.1
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Lodge, J.K.5
Jackson-Machelski, E.6
Gordon, J.I.7
Sikorski, J.A.8
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11
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0031889926
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Crystal structure of the anti-fungal target N-myristoyl transferase
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11 Weston, S. A., Gamble, R., Colls, J., Rosenbrock, G., Taylor, I., Egerton, M., Tucker, A. D., Tunnicliffe, A., Mistry, A., Mancia, F. et al. (1998) Crystal structure of the anti-fungal target N-myristoyl transferase. Nat. Struct. Biol. 5, 213-221
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Weston, S.A.1
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Tucker, A.D.7
Tunnicliffe, A.8
Mistry, A.9
Mancia, F.10
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12
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0031788774
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Structure of N-myristoyltransferase with bound myristoyl CoA and peptide substrate analogs
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12 Bhatnagar, R. S., Futterer, K., Farazi, T. A., Korolev, S., Murray, C. L., Jackson-Machelski, E., Gokel, G. W., Gordon, J. I. and Waksman, G. (1998) Structure of N-myristoyltransferase with bound myristoyl CoA and peptide substrate analogs. Nat. Struct. Biol. 5, 1091-1097
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Bhatnagar, R.S.1
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Jackson-Machelski, E.6
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13
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0032549571
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A second mammalian N-myristoyltransferase
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13 Giang, D. K. and Cravatt, B. F. (1998) A second mammalian N-myristoyltransferase. J. Biol. Chem. 273, 6595-6598
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Giang, D.K.1
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0032143539
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Characterization of human and rat brain myristoyl-CoA:Protein N-myristoyltransferase: Evidence for an alternative splice variant of the enzyme
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14 McIlhinney, R. A. J., Young, K., Egerton, M., Camble, R., White, A. and Soloviev, M. (1998) Characterization of human and rat brain myristoyl-CoA:protein N-myristoyltransferase: evidence for an alternative splice variant of the enzyme. Biochem. J. 333, 491-495
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Identification and characterization of multiple forms of bovine brain N-myristoyltransferase
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15 Glover, C. J. and Felsted, R. L. (1995) Identification and characterization of multiple forms of bovine brain N-myristoyltransferase. J. Biol. Chem. 270, 23226-23233
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Human N-myristoyltransferase amino-terminal domain involved in targeting the enzyme to the ribosomal subcellular fraction
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16 Glover, C. J., Hartman, K. D. and Felsted, R. L. (1997) Human N-myristoyltransferase amino-terminal domain involved in targeting the enzyme to the ribosomal subcellular fraction. J. Biol. Chem. 272, 28680-28689
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Isolation, expression and characterization of the gene for an ADP-ribosylation factor from the malarial parasite, Plasmodium falciparum
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17 Stafford, W. H. L., Stockley, R. W., Ludbrook, S. B. and Holder, A. A. (1996) Isolation, expression and characterization of the gene for an ADP-ribosylation factor from the malarial parasite, Plasmodium falciparum. Eur. J. Biochem. 242, 104-113
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0027451943
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A conserved parasite serine protease processes the Plasmodium falciparum merozoite surface protein-1 (MSP1)
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18 Blackman, M. J., Chappel, J. A., Shai, S. and Holder, A. A. (1993) A conserved parasite serine protease processes the Plasmodium falciparum merozoite surface protein-1 (MSP1). Mol. Biochem. Parasitol. 62, 103-114
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N-myristoyl transferase assay using phosphocellulose paper binding
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19 King, M. J. and Sharma, R. K. (1991) N-myristoyl transferase assay using phosphocellulose paper binding. Anal. Biochem. 199, 149-153
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0028298347
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Characterization of a polyhistidine-tagged form of human myristoyl-CoA:Protein N-myristoyltransferase produced in Escherichia coli
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20 McIlhinney, R. A. J., Patel, P. B. and McGlone, K. (1994) Characterization of a polyhistidine-tagged form of human myristoyl-CoA:protein N-myristoyltransferase produced in Escherichia coli. Eur. J. Biochem. 222, 137-146
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0025159275
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Protein N-myristoylation in Escherichia coli: Reconstitution of a eukaryotic protein modification in bacteria
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21 Duronio, R. J., Jackson-Machelski, E., Heuckeroth, R. O., Olins, P. O., Devine, C. S., Yonemoto, W., Slice, L. W., Taylor, S. S. and Gordon, J. I. (1990) Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria. Proc. Natl. Acad. Sci. U.S.A. 87, 506-510
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0028072831
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Fatty acyl transfer by human N-myristyl transferase is dependent upon conserved cysteine and histidine residues
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22 Peseckis, S. M. and Resh, M. D. (1994) Fatty acyl transfer by human N-myristyl transferase is dependent upon conserved cysteine and histidine residues. J. Biol. Chem. 269, 30888-30892
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