Inhibition of phospholipase Cγ1 and cancer cell proliferation by triterpene esters from Uncaria rhynchophylla

Journal of Natural Products

Volumn 63, Issue 6, 2000, Pages 753-756

  Lee, Ji Suk ^a   Kim, Jinwoong ^a   Kim, Bo Yeon ^b   Lee, Hyun Sun ^b   Ahn, Jong Seog ^b   Chang, Yuan Shiun ^c  

^a Seoul National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

INOSITOL PHOSPHATE; PHOSPHOLIPASE C INHIBITOR; PLANT EXTRACT; TRITERPENE DERIVATIVE; UNCARIA RHYNCHOPHYLA EXTRACT; UNCARINIC ACID; UNCLASSIFIED DRUG; ENZYME INHIBITOR; ESTER; ISOENZYME; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; TRITERPENE; UNCARINIC ACID C; UNCARINIC ACID D; UNCARINIC ACID E; UNCARINIC ACID-C; UNCARINIC ACID-D; UNCARINIC ACID-E;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; DOSE RESPONSE; DRUG ISOLATION; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; PLANT; PROTON NUCLEAR MAGNETIC RESONANCE; ANIMAL; CELL CULTURE; CELL DIVISION; CELL STRAIN 3T3; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; ISOLATION AND PURIFICATION; MEDICINAL PLANT; MOUSE; NEOPLASM; PATHOLOGY; RUBIACEAE; STRUCTURE ACTIVITY RELATION;

UNCARIA; UNCARIA RHYNCHOPHYLLA;

3T3 CELLS; ANIMALS; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ESTERS; HUMANS; ISOENZYMES; MICE; NEOPLASMS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PLANTS, MEDICINAL; RUBIACEAE; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES; TUMOR CELLS, CULTURED;

EID: 0034202794     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np990478k     Document Type: Article

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