Uncarinic acids: Phospholipase Cγ1 inhibitorsfrom hooks of Uncaria rhynchophylla

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 10, 1999, Pages 1429-1432

  Ji, Suk Lee ^a   Mi, Young Yang ^a   Yeo, Hosup ^a   Kim, Jinwoong ^a   Hyun, Sun Lee ^b   Jong, Seog Ahn ^b  

^a Seoul National University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHLOROFORM; METHANOL; PHOSPHOLIPASE C INHIBITOR; PLANT EXTRACT; TRITERPENE DERIVATIVE; UNCARIA RHYNCHOPHYLLA EXTRACT; UNCARINIC ACID A; UNCARINIC ACID B; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INFRARED SPECTROPHOTOMETRY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS;

CELL DIVISION; ENZYME INHIBITORS; HUMANS; ISOENZYMES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; OLEANOLIC ACID; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; RUBIACEAE; TUMOR CELLS, CULTURED;

EID: 0033577754     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00211-5     Document Type: Article

References (10)

1. Hill, S. R.; Bonjouklian, R.; Powis, G.; Abraham, R. T.; Ashendel, C. L.; Zalkow, L. H. Anti-Cancer Drug Design 1994, 9, 353; and references cited therein.
2. Lee, J. S.; Cho, Y. S.; Park, E. J.; Kim, J.; Oh, W. K.; Lee, H. S.; Ahn, J. S. J. Nat. Prod. 1998, 61, 867.
3. 7Na: 671.3924).
4. Ogunkoya, L. Phytochemistry 1981, 20, 121.
5. Shiojima, K.; Arai, Y.; Masuda, K.; Takase, Y.; Ageta, T.; Ageta, H. Chem. Pharm. Bull. 1992, 40, 1683.
6. Mahato, S. B.; Kundu, A. P. Phytochemistry 1994, 37, 1517.
7. Maillard, M.; Adewunmi, C. O.; Hostettmann, K. Phytochemistry 1992, 31, 1321.
8. Häberlein, H.; Tschiersch, K. P. Phytochemisrty 1994, 35, 765.
9. Rhee, S. G.; Ryu, S. H.; Lee, K. Y.; Cho, K. S. In Methods in Enzymology; Dennis, E. A., Ed.; Academic Press: New York, 1991, Vol. 197, pp. 502-511.
10. Monks, A.; Scudiero, D.; Skehan, P.; Shoemaker, R.; Paull, K.; Vistica, D.; Hose, C.; Langley, J.; Cronise, P.; Vaigro-Wolff, A.; Gray-Goodrich, M; Campbell, H.; Mayo, J.; Boyd, M. J. Natl. Cancer Inst. 1991, 83, 757.