A physiological ligand of positive selection is seen with high specificity

Journal of Immunology

Volumn 164, Issue 9, 2000, Pages 4601-4606

  Irion, Stefan ^a,b   Berg, Ranee E ^a,c   Staerz, Uwe D ^a,c  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN; PEPTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ANIMAL CELL; ARTICLE; CELL SELECTION; CELL SURFACE; COMPLEX FORMATION; CONCENTRATION RESPONSE; GENE MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0034193190     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.9.4601     Document Type: Article

References (43)

1. Bevan, M. J. 1977. In a radiation chimaera, host H-2 antigens determine immune responsiveness of donor cytotoxic cells. Nature 269:417.
2. Fink, P. J., and M. J. Bevan. 1978. H-2 antigens of the thymus determine lymphocyte specificity. J. Exp. Med. 148:766.
3. Zinkernagel, R. M., G. N. Callahan, A. Althage, S. Cooper, P. A. Klein, and J. Klein. 1978. On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition? J. Exp. Med. 147:882.
4. Berg, L. J., G. D. Frank, and M. M. Davis. 1990. The effects of MHC gene dosage and allelic variation on T cell receptor selection. Cell 60:1043.
5. Nikolic-Zugic, J., and M. J. Bevan. 1990. Role of self-peptides in positively selecting the T-cell repertoire. Nature 344:65.
6. + T cells in the thymus. Cell 73:1041.
7. + T cells induced by major histocompatibility complex binding peptides in fetal thymic organ culture. J. Exp. Med 177:1469.
8. Kappler, J. W., N. Roehm, and P. Marrack. 1987. T cell tolerance by clonal elimination in the thymus. Cell 49:273.
9. + thymocytes. Nature 333:742.
10. Sha, W. C., C. A. Nelson, R. D. Newberry, D. M. Kranz, J. H. Russell, and D. Y. Loh. 1988. Positive and negative selection of an antigen receptor on T cells in transgenic mice. Nature 336:73.
11. Ramsdell, F., T. Lantz, and B. J. Fowlkes. 1989. A nondeletional mechanism of thymic self tolerance. Science 246:1038.
12. Roberts, J. L., S. O. Sharrow, and A. Singer. 1990. Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities. J. Exp. Med. 171:935.
13. Speiser, D. E., Y. Chvatchko, R. M. Zinkernagel, and H. R. MacDonald. 1990. Distinct fates of self-specific T cells developing in irradiation bone marrow chimeras: clonal deletion, clonal anergy, or in vitro responsiveness to self-M1s-1a controlled by hemopoietic cells in the thymus. J. Exp. Med. 172:1305.
14. Ashton-Rickardt, P. G., A. Bandeira, J. R. Delaney, L. Van Kaer, H. P. Pircher, R. M. Zinkemagel, and S. Tonegawa. 1994. Evidence for a differential avidity model of T cell selection in the thymus. Cell 76:651.
15. Hogquist, K. A., S. C. Jameson, W. R. Heath, J. L. Howard, M. J. Bevan, and F. R. Carbone. 1994. T cell receptor antagonist peptides induce positive selection. Cell 76:17.
16. Sebzda, E., V. A. Wallace, J. Mayer, R. S. Yeung, T. W. Mak, and P. S. Ohashi. 1994. Positive and negative thymocyte selection induced by different concentrations of a single peptide. Science 263:1615.
17. Jameson, S. C., K. A. Hogquist, and M. J. Bevan. 1994. Specificity and flexibility in thymic selection. Nature 369:750.
18. Pawlowski, T. J., M. D. Singleton, D. Y. Loh, R. Berg, and U. D. Staerz. 1996. Permissive recognition during positive selection. Eur. J. Immunol. 26:851.
19. Schumacher, T. N., and H. L. Ploegh. 1994. Are MHC-bound peptides a nuisance for positive selection? Immunity 1:721.
20. Jameson, S. C., K. A. Hogquist, and M. J. Bevan. 1995. Positive selection of thymocytes. Annu. Rev. Immunol. 13:93.
21. Bevan, M. J., K. A. Hogquist, and S. C. Jameson. 1994. Selecting the T cell receptor repertoire. Science 264:796.
22. Barton, G. M., and A. Y. Rudensky. 1999. Requirement for diverse, low-abundance peptides in positive selection of T cells. Science 283:67.
23. Berg, R. E., M. F. Princiotta, S. Irion, J. A. Moticka, K. R. Dahl, and U. D. Staerz. 1999. Positive selection of an H2-M3 restricted T cell receptor. Immunity 11:33.
24. Princiotta, M. F., L. L. Lenz, M. J. Bevan, and U. D. Staerz. 1998. H2-M3 restricted presentation of a Listeria-derived leader peptide. J. Exp. Med. 187: 1711.
25. Shawar, S. M., R. G. Cook, J. R. Rodgers, and R. R. Rich. 1990. Specialized functions of MHC class I molecules. I. An N-formyl peptide receptor is required for construction of the class I antigen Mta. J. Exp. Med. 171:897.
26. Loveland, B., C. R. Wang, H. Yonekawa, E. Hermel, and K. F. Lindahl. 1990. Maternally transmitted histocompatibility antigen of mice: a hydrophohic peptide of a mitochondrially encoded protein. Cell 60:971.
27. Lindahl, K. F., D. E. Byers, V. M. Dabhi, R. Hovik, E. P. Jones, G. P. Smith, C. R. Wang, H. Xiao, and M. Yoshino. 1997. H2-M3, a full-service class Ib histocompatibility antigen. Annu. Rev. Immunol. 15:851.
28. Wang, C. R., A. R. Castano, P. A. Peterson, C. Slaughter, K. F. Lindahl, and J. Deisenhofer. 1995. Nonclassical binding of formylated peptide in crystal structure of the MHC class Ib molecule H2-M3. Cell 82:655.
29. Vyas, J. M., R. R. Rich, D. D. Howell, S. M. Shawar, and J. R. Rodgers. 1994. Availability of endogenous peptides limits expression of an M3a-Ld major histocompatibility complex class I chimera. J. Exp. Med. 179:155.
30. Kubo, R. T., W. Born, J. W. Kappler, P. Marrack, and M. Pigeon. 1989. Characterization of a monoclonal antibody which detects all murine αβ T cell receptors. J. Immunol. 142:2736.
31. Staerz, U. D., H. G. Rammensee, J. D. Benedetto, and M. J. Bevan. 1985. Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor. J. Immunol. 134:3994.
32. Ozato, K., G. A. Evans, B. Shykind, D. H. Margulies, and J. G. Seidman. 1983. Hybrid H-2 histocompatibility gene products assign domains recognized by alloreactive T cells. Proc. Natl. Acad. Sci. USA 80:2040.
33. Lenz, L. L., B. Dere, and M. J. Bevan. 1996. Identification of an H2-M3-restricted Listeria epitope: implications for antigen presentation by M3. Immunity 5:63.
34. Wang, C. R., and K. F. Lindahl. 1993. HMT, encoded by H-2 M3, is a neoclassical major histocompatibilily class I antigen. Proc. Natl. Acad. Sci. USA 90: 2784.
35. Rammensee, H. G., K. Falk, and O. Rotzschke. 1993. Peptides naturally presented by MHC class I molecules. Annu. Rev. Immunol. 11:213.
36. Vyas, J. M., J. R. Rodgers, and R. R. Rich. 1995. H-2 M3a violates the paradigm for major histocompatibility complex class I peptide binding. J. Exp. Med. 181: 1817.
37. Dabhi, V. M., and K. F. Lindahl. 1998. Short peptides sensitize target cells to CTL specific for the MHC class Ib molecule, H2-M3. Eur. J. Immunol. 28:3773.
38. Vyas, J. M., S. M. Shawar, J. R. Rodgers, R. G. Cook, and R. R. Rich. 1992. Biochemical specificity of H-2 M3a: stereospecificity and space-filling requirements at position 1 maintain N-formyl peptide binding. J. Immunol. 149:3605.
39. Alam, S. M., P. J. Travers, J. L. Wung, W. Nasholds, S. Redpath, S. C. Jameson. and N. R. Gascoigne. 1996. T-cell-receptor affinity and thymocyte positive selection. Nature 381:616.
40. Rohren, E. M., D. J. McCormick, and L. R. Pease. 1994. Peptide-induced conformational changes in class 1 molecules: direct detection by flow cytometry. J. Immunol. 152:5337.
41. Calbo, S., G. Guichard, P. Bousso, S. Muller, P. Kourilsky, J. P. Briand, and J. P. Abastado. 1999. Role of peptide backbone in T cell recognition. J. Immunol. 162:4657.
42. Chen, W., J. McCluskey, S. Rodda, and F. R. Carbone. 1993. Changes at peptide residues buried in the major histocompatibility complex (MHC) class 1 binding cleft influence T cell recognition: a possible role for indirect conformational alterations in the MHC class I or bound peptide in determining T cell recognition. J. Exp. Med. 177:869.
43. Chiu, N. M., T. Chun, M. Fay, M. Mandal, and C. R. Wang. 1999. The majority of H2-M3 is retained intracellularly in a peptide-receptive state and traffics to the cell surface in the presence of N-formylated peptides. J. Exp. Med. 190:423.