Role of peptide backbone in T cell recognition

Journal of Immunology

Volumn 162, Issue 8, 1999, Pages 4657-4662

  Calbo, Sébastien ^a   Guichard, Gilles ^b   Bousso, Philippe ^a   Muller, Sylviane ^b   Kourilsky, Philippe ^a   Briand, Jean Paul ^b   Abastado, Jean Pierre ^a,c  

^a INSERM   (France)

^b INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c Immuno Designed Molecules   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIGENICITY; ARTICLE; CELL FUNCTION; CRYSTAL STRUCTURE; EFFECTOR CELL; HYBRIDOMA; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR RECOGNITION; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; T LYMPHOCYTE ACTIVATION;

ANIMALS; CLONE CELLS; H-2 ANTIGENS; HLA-C ANTIGENS; HYBRIDOMAS; MICE; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0033561631     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Townsend, A., and H. Bodmer. 1989. Antigen recognition by class I-restricted T lymphocytes. Annu. Rev. Immunol. 7:601.
2. Engelhard, V. 1994. Structure of peptides associated with MHC class I molecules. Curr. Opin. Immunol. 6:13.
3. Momburg, F., J. Roelse, G. J. Hammerling, and J. J. Neefjes. 1994. Peptide size selection by the major histocompatibility complex-encoded peptide transporter J. Exp. Med. 179:1613.
4. Schumacher, T. N., D. V. Kantesaria, M. T. Heemels, P. G. Ashton-Rickardt, J. C. Shepherd, K. Fruh, Y. Yang, P. A. Peterson, S. Tonegawa, and H. L. Ploegh. 1994. Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator. J. Exp. Med. 179:533.
5. Guo, H. C., T. S. Jardetzky, T. P. Garrett, W. S. Lane, J. L. Strominger, and D. C. Wiley. 1992. Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle. Nature 360:364.
6. Matsumura, M., D. H. Fremont, P. A. Peterson, and I. A. Wilson. 1992. Emerging principles for the recognition of peptide antigens by MHC class 1 molecules Science 257:927.
7. d influence peptide presentation. Int. Immunol. 4:945.
8. Latron, F., L. Pazmany, J. Morrison, R. Moots, M. A. Saper, A. McMichael, and J. L. Strominger. 1992. A critical role for conserved residues in the cleft of HLA-A2 in presentation of a nonapeptide to T cells. Science 257:964.
9. Guichard, G., S. Calbo, S. Muller, P. Kourilsky, J. P. Briand, and J. P. Abastado. 1995. Efficient binding of reduced peptide bond pseudopeptides to major histocompatibility complex class I molecule. J. Biol. Chem. 270:26057.
10. von Boehmer, H. 1994. Positive selection of lymphocytes. Cell 76:219.
11. Jameson, S. C., K. A. Hogquist, and M. J. Bevan. 1995. Positive selection of thymocytes. Annu. Rev. Immunol. 13:93.
12. Sant'Angelo, D. B., P. G. Waterbury, B. E. Cohen, W. D. Martin, L. Van Kaer, A. C. Hayday, and C. A. Janeway, Jr. 1997. The imprint of intrathymic self-peptides on the mature T cell receptor repertoire. Immunity 7:517.
13. Tanchot, C., M. M. Rosado, F. Agenes, A. A. Freitas, and B. Rocha. 1997. Lymphocyte homeostasis. Semin. Immunol. 9:331.
14. Ding, Y. H., K. J. Smith, D. N. Garboczi, U. Utz, W. E. Biddison, and D. C. Wiley. 1998. Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids. Immunity 8:403.
15. Garboczi, D. N., P. Ghosh, U. Utz, Q. R. Fan, W. E. Biddison, and D. C. Wiley. 1996. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 384:134.
16. Garcia, K. C., M. Degano, R. L. Stanfield, A. Brunmark, M. R. Jackson, P. A. Peterson, L. Teyton, and I. A. Wilson. 1996. An αβ T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex. Science 274:209.
17. Garcia, K. C., M. Degano, L. R. Pease, M. Huang, P. A. Peterson, L. Teyton, and I. A. Wilson. 1998. Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen. Science 279:1166.
18. d peptide complexes. Immunity 8:553.
19. d restricted antigenic peptides. Int. Immunol. 3:1035.
20. Neimark, J., and J. P. Briand. 1993. Development of a fully automated multichannel peptide synthesizer with integrated TFA cleavage capability. Pept. Res. 6:219.
21. Abastado, J. P., Y. C. Lone, A. Casrouge, G. Boulot, and P. Kourilsky. 1995. Dimerization of soluble MHC-peptide complexes is sufficient for activation of T-cell hybridoma and induction of unresponsiveness. J. Exp. Med. 182:439.
22. d binding peptides and induction of peptide specific CTL. J. Immunol. Methods 176:245.
23. 50) of an enzymatic reaction. Biochem. Pharmacol. 22:3099.
24. Bellio, M., Y.-C. Lone, O. de la Calle-Martin, B. Malissen, J.-P. Abastado, and P. Kourilsky. 1994. The Vβ CDR1 region of an MHC Class I-restricted TCR is involved in the recognition of peptide/MHC I and superantigen/MHC II complex. J. Exp. Med. 179:1087.
25. Casanova, S., F. Martinon, H. Gournier, C. Barra, C. Pannetier, A. Regnault, P. Kourilsky, J. Cerottini, and J. Maryanski. 1993. TCR selection by and recognition of two class I MHC-restricted antigenic peptides that differ at a single position. J. Exp. Med. 177:811.
26. Letourneur, F., and B. Malissen. 1989. Derivation of a T cell hybridoma variant deprived of functional T cell receptor α and β chain transcripts reveals a non-functional α-mRNA of BW5147 origin. Eur. J. Immunol. 19:2269.
27. Cerottini, J. C., H. D. Engers, H. R. Macdonald, and T. Brunner. 1974. Generation of cytotoxic T lymphocytes in vitro. I. Response of normal and immune mouse spleen cells in mixed leukocyte cultures. J. Exp. Med. 140:703.
28. d-restricted cloned CTL specific for a photoreactive peptide derivative. Immunity 3:51.
29. Garboczi, D. N., D. T. Hung, and D. C. Wiley. 1992. HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peplides. Proc. Natl. Acad. Sci. USA 89: 3429.
30. Altman, J. D., P. A. H. Moss, P. J. R. Goulder, D. H. Barouch, M. G. McHeyzer-Williams, J. I. Bell, A. J. McMichael, and M. M. Davis. 1996. Phenotypic analysis of antigen-specific T lymphocytes. Science 274:94.
31. Bousso, P., A. Casrouge, J. D. Altman, M. Haury, J. Kanellopoulos, J.-P. Abastado, and P. Kourilsky. 1998. Individual variations in the murine T cell response to a specific peptide reflect variability in naive repertoires. Immunity 9:169.
32. Sasaki, Y., and D. H. Coy. 1987. Solid phase synthesis of peptides containing the CH2NH peptide bond isostere. Peptides 8:119.
33. Garcia, K. C., C. A. Scott, A. Brunmark, F. R. Carbone, P. A. Peterson, I. A. Wilson, and L. Teyton. 1996. CD8 enhances formation of stable T-cell receptor/MHC class I molecule complexes. Nature 384:577.
34. b. Science 257:919.
35. b molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc. Natl. Acad. Sci. USA 89:8403.
36. Silver, M., H.-C. Guo, J. Strominger, and D. Wiley. 1992. Atomic structure of a human MHC molecule presenting an influenza virus peptide. Nature 360:367.
37. b at 2.4 Å resolution: implications for antigen-determinant selection. Cell 76:39.
38. Madden, D., D. Garboczi, and D. Wiley. 1993. The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. Cell 75:693.
39. Pullen, J. K., R. M. Horton, Z. L. Cai, and L. R. Pease. 1992. Structural diversity of the classical H-2 genes: K, D, and L. J. Immunol. 148:953.
40. Parham, P., E. J. Adams, and K. L. Arnett. 1995. The origins of HLA-A,B,C polymorphism. Immunol. Rev. 143:141.
41. Abastado, J.-P., A. Casrouge, and P. Kourilsky. 1993. Differential role of conserved and polymorphic residues of the binding groove of MHC class I molecules in the selection of peptides. J. Immunol. 151:3569.
42. Luescher, I. F., E. Vivier, A. Layer, J. Mahiou, F. Godeau, B. Malissen, and P. Romero. 1995. CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes. Nature 373:353.
43. Norment, A. M., R. D. Salter, P. Parham, V. H. Engelhard, and D. R. Littman. 1988. Cell-cell adhesion mediated by CD8 and MHC class I molecules. Nature 336:79.
44. Crawford, F., H. Kozono, J. White, P. Marrack, and J. Kappler. 1998. Detection of antigen-specific T cells with multivalent soluble class 11 MHC covalent peptide complexes. Immunity 8:675.
45. Tong, L., S. Pav, C. Pargellis, F. Do, D. Lamarre, and P. C. Anderson. 1993. Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures. Proc. Natl. Acad. Sci. USA 90:8387.
46. Miller, M., J. Schneider, B. K. Sathyanarayana, M. V. Toth, G. R. Marshall, L. Clawson, L. Selk, S. B. Kent, and A. Wlodawer. 1989. Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution. Science 246:1149.
47. Boehncke, W. H., T. Takeshita, C. D. Pendleton, R. A. Houghten, S. Sadegh-Nasseri, L. Racioppi, J. A. Berzofsky, and R. N. Germain. 1993. The importance of dominant negative effects of amino acid side chain substitution in peptide-MHC molecule interactions and T cell recognition. J. Immunol. 150:331.