Inversion of the cis geometry requirement for cytotoxicity in structurally novel platinum(II) complexes containing the bidentate N,O-donor pyridin-2-yl-acetate

Inorganic Chemistry

Volumn 39, Issue 9, 2000, Pages 1882-1890

  Bierbach, Ulrich ^a,c   Sabat, Michal ^b   Farrell, Nicholas ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c WAKE FOREST UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; CHELATING AGENT; CISPLATIN; GUANOSINE PHOSPHATE; LIGAND; PLATINUM COMPLEX; PYRIDIN 2 YL ACETATE; PYRIDIN-2-YL ACETATE; PYRIDINE DERIVATIVE; TRANSPLATIN;

ANIMAL; ANIMAL CELL; ARTICLE; CONFORMATION; CYTOTOXICITY; DRUG ACTIVITY; DRUG STRUCTURE; INFRARED SPECTROSCOPY; ISOMERISM; LEUKEMIA L 1210; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; SOLUBILITY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

5'-GUANYLIC ACID; ACETATES; ANIMAL; ANTINEOPLASTIC AGENTS; CHELATING AGENTS; CISPLATIN; CRYSTALLOGRAPHY, X-RAY; LEUKEMIA L1210; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR CONFORMATION; ORGANOPLATINUM COMPOUNDS; PYRIDINES; SOLUBILITY; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.;

EID: 0034189944     PISSN: 00201669     EISSN: None     Source Type: Journal    
DOI: 10.1021/ic991259p     Document Type: Article

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