Expression of leukemia inhibitory factor in human pituitary adenomas: A morphologic and immunocytochemical study

Pituitary

Volumn 2, Issue 4, 2000, Pages 245-251

  Kontogeorgos, George ^a,b,d   Patralexis, Haris ^a   Tran, Ami ^b   Kovacs, Kalman ^b   Melmed, Shlomo ^c  

^a G GENNIMATAS GENERAL HOSPITAL   (Greece)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KAT HOSPITAL   (Greece)

Author keywords

Adenoma; Immunohistochemistry; LIF; Pathology; Pituitary

Indexed keywords

GROWTH INHIBITOR; INTERLEUKIN 6; LEUKEMIA INHIBITORY FACTOR; LIF PROTEIN, HUMAN; LYMPHOKINE; PARAFFIN;

ADENOMA; ARTICLE; CLASSIFICATION; GOLGI COMPLEX; HUMAN; HYPOPHYSIS TUMOR; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; PATHOLOGY;

ADENOMA; GOLGI APPARATUS; GROWTH INHIBITORS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LYMPHOKINES; PARAFFIN EMBEDDING; PITUITARY NEOPLASMS;

EID: 0034186353     PISSN: 1386341X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Ray D, Melmed S. Pituitary cytokine and growth factor expression and action. Endocr Rev 1997;18:206-228.
2. Tsagarakis S, Kontogeorgos G, Kovacs K. The role of cytokines in the normal and neoplastic pituitary. Crit Rev Oncol/Hematol 1998;28:73-90.
3. Ichikawa Y. Differentiation of a cell line of myeloid leukemia. J Cell Physiol 1969;74:223-234.
4. Metcalf D. Clonal analysis of the action of GM-CFD on the proliferation and differentiation of myelomonocytic leukemic cells. Int J Cancer 1979;24:616-623.
5. Gearing DP, Gough NM, King JA, Hilton DJ, Nicola NA, Simpson RJ, Nice EC, Kelso A, Metcalf D. Molecular cloning and expression of cDNA encoding a murine myeloid leukaemia inhibitory factor (LIF). EMBO J 1987;20:3995-4002.
6. Auernhammer CJ, Melmed S. Interleukin-11 stimulates proopiomelanocortin gene expression and adrenocorticotropin secretion in corticotroph cells: Evidence for a redundant cytokine network in the hypothalamo-pituitary-adrenal axis. Endocrinology 1999;140:1559-1566.
7. Ferrara N, Winer J, Henzel WJ. Pituitary follicular cells secrete an inhbitor of aortic endothelial cell growth: Identification as leukemia inhibitory factor. Proc Natl Acad Sci USA 1992;89:698-702.
8. Akita S, Webster J, Ren SG, Takino H, Said J, Zand O, Melmed S. Human and murine pituitary expression of leukemia inhibitory factor. Novel intrapituitary regulation of adrenocorticotropin hormone synthesis and secretion. J Clin Invest 1995;95:1288-1298.
9. Kontogeorgos G, Kapranos N, Vamvassakis E, Papadopoulos N. DNA ploidy of pituitary adenomas assessed by image analysis. Anal Quant Cytol Histol 1996;18:144-150.
10. Werner M, Von Wasielewski R, Komminoth P. Antigen retrieval, signal amplification and intensification in immunohistochemistry. Histochem Cell Biol 1996;105:253-260.
11. Kitamura T, Tange T, Terasawa T, Chiba S, Kuwaki T, Miyagawa K, Piao YF, Miyazono K, Urabe A, Takaku F. Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin. J Cell Physiol 1989;140:323-334.
12. Sinicrope FA, Ruan SB, Cleary KR, Stephens LC, Lee J, Levin B. Bcl-2 and p53 oncoprotein expression during colorectal tumorigensis. Cancer Res 1995;55:237-241.
13. Wheaton S, Netser J, Guinee D, Rahn M, Perkins S. bcl-2 and Bax protein expression in indolent versus aggressive B-cell Non-Hodgkin lymphomas. Hum Pathol 1998;29:820-825.
14. Chesnokova V, Auernhammer CJ, Melmed S. Murine leukemia inhibitory factor gene disruption attenuates the hypothalamo-pituitary-adrenal axis stress response. Endocrinology 1998;139:2209-2216.
15. Kontogeorgos G, Patralexis H, Kovacs K, Horvath E, Tran A, Melmed S. Immunocytochemical localization of leukemia inhibitory factor in various morphologic types of human pituitary adenomas. Abstracts 6th International Pituitary Congress, p. 102, Long Beach, June 1999.
16. Elias KA, Weiner RI. Inhibition of estrogen-induced anterior pituitary enlargement and arteriogenesis by bromocriptine in Fischer 344 rats. Endocrinology 1987;120:617-621.
17. Stepien H, Grochal M, Zielinski KW, Mucha S, Kunert-Radek J, Kulig A, Stawowy A, Pisarek H. Inhibitory effects of fumagillin and its analogue TNP-470 on the function, morphology and angiogenesis of an oestrogen-induced prolactinoma in Fischer 344 rats. J Endocrinol 1996;150:99-106.
18. Akita S, Readhead C, Stefaneau L, Fine J, Tampanaru-Sarmesiu A, Kovacs K, Melmed S. Pituitary-directed leukemia inhibitory factor transgene forms Rathke's cleft cysts and impairs adult pituitary function. A model for human pituitary Rathke's cysts. J Clin Invest 1997;99:2462-2469.
19. Tran A, Kovacs K, Stefaneanu L, Kontogeorgos G, Scheithauer BW, Melmed S. Expression of leukemia inhibitory factor in craniopharyngioma. Endocr Pathol 1999;10:103-108.
20. Montero-Julian FA, Brailly H, Sautes C, Joyeux I, Dorval T, Mosseri V, Yasukawa K, Wijdenes J, Adler A, Gorin I, Fridman WH. Tartour E. Characterization of soluble gp 130 released by melanoma cell lines: A polyvalent antagonist of cytokines from the interleukin 6 family. Clin Cancer Res 1973;1443-1451.
21. Ren SG, Seliktar J, Li X, Braunstein GD, Melmed S. Measurement of leukemia inhibitory factor in biological fluids by radioimmunoassay. J Clin Endocrinol Metab 1998;83:1275-1283.
22. Gascan H, Anegon I, Praloran V, Naulet J, Godard A, Soulliou JP, Jaques Y. Constitutive production of human interleukin for DA cells/leukemia inhibitory factor by human tumor cell lines derived from various tissues. J Immunol 1990;144:2592-2598.
23. Kamohara H, Sakamoto K, Ishiko T, Mita S, Masuda Y, Abe T, Ogawa M. Human carcinoma cell lines produce biologically active leukemia inhibitory factor. Res Commun Mol Pathol Pharmacol 1994;85:131-139.
24. Kellokumpu-Lehtinen P, Talpaz M, Harris D, Van Q, Kurzock R, Estrov Z. Leukemia inhibitory factor stimulates breast, kidney and prostate cancer cell proliferation by paracrine and autocrine pathways. Int J Cancer 1996;66:515-519.