Complex segregation analysis of deafness in Dalmatians

American Journal of Veterinary Research

Volumn 61, Issue 5, 2000, Pages 550-553

  Famula, Thomas R ^a   Oberbauer, Anita M ^a   Sousa, Candace A ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Animal Dermatology Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

ALLELE; ANIMAL; ANIMAL DISEASE; ARTICLE; BIOLOGICAL MODEL; DOG; DOG DISEASE; EAR; EVOKED BRAIN STEM AUDITORY RESPONSE; EYE COLOR; FEMALE; GENETICS; HAIR COLOR; HEARING IMPAIRMENT; MALE; PEDIGREE; PHENOTYPE; PHYSIOLOGY; PREVALENCE; REGRESSION ANALYSIS; REGULATOR GENE; SEX DIFFERENCE; STATISTICAL MODEL; UNITED STATES;

ALLELES; ANIMALS; CALIFORNIA; DEAFNESS; DOG DISEASES; DOGS; EAR; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; EYE COLOR; FEMALE; HAIR COLOR; LOCUS CONTROL REGION; LOGISTIC MODELS; MALE; MODELS, GENETIC; PEDIGREE; PHENOTYPE; PREVALENCE; REGRESSION ANALYSIS; SEX FACTORS;

EID: 0034181460     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2000.61.550     Document Type: Article

References (14)

1. Steel KP, Brown SDM. More deafness genes. Science 1998;280:1403.
2. Verhoeven K, Van Laer L, Kirschhofer K, et al. Mutations in the human alpha-tectorin gene cause autosomal non-syndromic hearing impairment. Nat Genet 1998;19:60-62.
3. Probst FJ, Fridell RA, Raphael Y, et al. Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene. Science 1998;280:1444-1447.
4. Wang A, Laing Y, Fridell RA, et al. Association of unconventional myosin MYO15 mutations with the human nonsyndromic deafness DFNB3. Science 1998;280:1447-1451.
5. Famula TR, Oberbauer AM, Sousa CA. A threshold model analysis of deafness in Dalmatians. Mammalian Genome 1996;7:650-653.
6. Bonney GE. Regressive logistic models for familial disease and other binary traits. Biometrics 1986;42:611-625.
7. Bonney GE, Dunston GM, Wilson J. Regressive logistic models for ordered and unordered polychotomous traits: application to affective disorders. Genet Epidemiol 1989;6:211-215.
8. Greibrokk T. Hereditary deafness in the Dalmatian: relationship to eye and coat color. J. Am Anim Hosp Assoc 1994;30:170-176.
9. Van Tassell CP, Van Vleck LD. A manual for the use of MTGSAM. A set of Fortran programs to apply Gibbs sampling to animal models in variance component estimation. USDA Agricultural Research Service 1995;7-23.
10. Akaike H. A new look at the statistical model identification. IEEE Trans On Automatic Control. 1974;AC-19:716-723.
11. Mood AM, Graybill FA, Boes DC. Introduction to the theory of statistics. 3rd ed. New York: McGraw-Hill Book Co, 1974;440-441.
12. Claus EB, Schildkraut J, Iverson ES Jr, et al. Effect of BRCA1 and BRCA2 in the association between breast cancer risk and family history. J Nat Cancer Inst 1998;16:2417-2425.
13. Wood JLN, Lakhani KH. Prevalence and prevention of deafness in the Dalmatian - assessing the effect of parental hearing status and gender using ordinary logistic and generalized random litter effect models. Vet J 1997;154:121-133.
14. Wood JLN, Lakhani KH. Deafness in Dalmatians: does sex matter? Prev Vet Med 1998;36:39-50.