Ca2+-bound calmodulin forms a compact globular structure on binding four trifluoperazine molecules in solution

Biochemical Journal

Volumn 347, Issue 1, 2000, Pages 211-215

  Matsushima, Norio ^a   Hayashi, Nobuhiro ^b   Jinbo, Yuji ^c   Izumi, Yoshinobu ^c  

^a SAPPORO MEDICAL UNIVERSITY   (Japan)

^b FUJITA HEALTH UNIVERSITY   (Japan)

^c YAMAGATA UNIVERSITY   (Japan)

Author keywords

Antagonist; Ca2+ binding protein; Globular form; Solution X ray scattering; Structural change

Indexed keywords

CALCIUM BINDING PROTEIN; CALCIUM ION; CALMODULIN; GLOBULAR PROTEIN; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; TRIFLUOPERAZINE; CALCIUM; RECOMBINANT PROTEIN; SULFONAMIDE;

ARTICLE; PRIORITY JOURNAL; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY; ANIMAL; BINDING SITE; CHEMISTRY; KINETICS; METABOLISM; RAT; SOLUTION AND SOLUBILITY; X RAY DIFFRACTION;

ANIMALS; BINDING SITES; CALCIUM; CALMODULIN; KINETICS; RATS; RECOMBINANT PROTEINS; SOLUTIONS; SULFONAMIDES; TRIFLUOPERAZINE; X-RAY DIFFRACTION;

EID: 0034177673     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3470211     Document Type: Article

References (52)

1. 1 Eldik, L. J. V. and Watterson, D. M. (1998) Calmodulin and Calcium Signal Transduction, Academic Press, San Diego
2. 2 Means, A. R., VanBerkum, M. F. A., Bagchi, I., Lu, K. P. and Rasmussen, C. D. (1991) Pharmacol. Ther. 50, 255-270
3. 3 Vogel, H. J. (1994) Biochem. Cell. Biol. 72, 357-376
4. 4 James, P., Vorherr, T. and Carafoli, E. (1995) Trends Biochem. Sci. 20, 38-42
5. 5 Finn, B. E., Evenas, J., Drakenberg, T., Waltho, J. P., Thulin, E. and Forsen, S. (1995) Nat. Struct. Biol. 2, 777-783
6. 6 Kretsinger, R. H., Rudnick, S. E. and Weissman, L. J. (1986) J. Inorg. Biochem. 28, 289-302
7. 7 Kuboniwa, H., Tjandra, N., Grzesiek, S., Ren, H., Klee, C. B. and Bax, A. (1995) Nat. Struct. Biol. 2, 768-776
8. 8 Zhang, M., Tanaka, T. and Ikura, M. (1995) Nat. Struct. Biol. 2, 758-567
9. 9 Seaton, B. A., Head, J. F., Engelman, D. M. and Richards, F. M. (1985) Biochemistry 24, 6740-6743
10. 10 Heidorn, D. B. and Trewhella, J. (1988) Biochemistry 27, 909-915
11. 11 Persechini, A. and Kretsinger, R. H. (1988) J. Biol. Chem. 263, 12175-12178
12. 12 Barbato, G., Ikura, M., Kay, L. E., Pastor, R. W. and Bax, A. (1992) Biochemistry 31, 5269-5278
13. 13 Ikura, M., Clore, G. M., Gronenborn, A. M., Zhu, G., Klee, C. B. and Bax, A. (1992) Science 256, 632-638
14. 14 Meador, W. E., Means, A. R. and Quiocho, F. A. (1992) Science 257, 1251-1255
15. 15 Meador, W. E., Means, A. R. and Quiocho, F. A. (1993) Science 262, 1718-1721
16. 16 Levin, R. M. and Weiss, B. (1977) Mol. Pharmacol. 13, 690-697
17. 17 Levin, R. M. and Weiss, B. (1979) Pharmacol. Exp. Ther. 208, 454-459
18. 18 Massom, L., Lee, H. and Jarrett, H. W. (1990) Biochemistry 29, 671-681
19. 19 Marshak, D. R., Lukas, T. J. and Watterson, D. M. (1985) Biochemistry 24, 144-150
20. 20 DeLaLuz, P. J., Golinski, M., Watt, D. S. and Vanaman, T. C. (1995) Bioconj. Chem. 6, 558-588
21. 21 Klevit, R. E., Levine, B. A. and Williams, R. J. P. (1981) FEBS Lett. 123, 25-29
22. 22 Forsen, S., Thulin, E., Drakenberg, T., Krebs, J. and Seamon, K. (1980) FEBS Lett. 117, 189-194
23. 23 Krebs, J. and Carafoli, E. (1982) Eur. J. Biochem. 124, 619-627
24. 24 Hidaka, H., Yamaki, T., Naka, M., Tanaka, T., Hayashi, H. and Kobayashi, R. (1979) Mol. Pharmacol. 17, 66-72
25. 25 Craven, C. J., Whitehead, B., Jones, S. K. A., Thulin, E., Blackburn, G. M. and Waltho, J. P. (1996) Biochemistry 35, 10287-10299
26. 26 Osawa, M., Swindells, M. B., Tanikawa, J., Tanaka, T., Mase, T., Furuya, T. and Ikura, M. (1998) J. Mol. Biol. 276, 165-176
27. 27 Dalgarno, D. C., Klevit, R. E., Levine, B. A., Scott, G. M. M., Williams, R. J. P., Gergely, J., Grabarek, Z., Leavis, P. C., Grand, R. J. A. and Drabikowski, W. (1984) Biochim. Biophys. Acta 791, 164-172
28. 28 Hickie, R. A., Vandonselaar, M., Quail, J. W. and Delbaere, L. T. J. (1997) J. Protein Eng. 10, 47
29. 29 Cook, W. J., Walter, L. J. and Walter, M. R. (1994) Biochemistry 33, 15259-15265
30. 30 Vandonselaar, M., Hickie, R. A., Quail, J. W. and Delbaere, L. T. J. (1994) Nat. Struct. Biol. 1, 795-801
31. 31 Vertessy, B. G., Harmat, V., Bocskei, Z., Naray-Szabo, G., Orosz, F. and Ovadi, J. (1998) Biochemistry 37, 15300-15310
32. 32 Osawa, M., Kuwamoto, S., Izumi, Y., Yap, K. L., Ikura, M., Shibanuma, T., Yokokura, H., Hidaka, H. and Matsushima, N. (1999) FEBS Lett. 442, 173-177
33. 33 Shimizu, T. and Hatano, M. (1983) FEBS Lett. 160, 132-136
34. 34 Shimizu, T., Hatano, M., Muto, Y. and Nozawa, Y. (1984) FEBS Lett. 166, 373-377
35. 35 Hayashi, N., Matsubara, M., Takasaki, A., Titani, K. and Taniguchi, H. (1998) Protein Express. Purif. 12, 25-28
36. 36 Ueki, T., Hiragi, Y., Kataoka, M., Inoko, Y., Amemiya, Y., Izumi, Y., Tagawa, H. and Muroga, Y. (1985) Biophys. Chem. 23, 115-124
37. 37 Guinier, A. (1939) Ann. Phys. 12, 166-237
38. 38 Glatter, O. (1982) in Small Angle X-Ray Scattering (Glatter, O. and Kratky, O., eds.), pp. 119-196, Academic Press, New York
39. 39 Matsushima, N., Izumi, Y. and Aoba, T. (1998) J. Biochem. (Tokyo) 123, 150-156
40. 40 Matsushima, N., Izumi, Y., Matsuo, T., Yoshino, H., Ueki, T. and Miyake, Y. (1989) J. Biochem. (Tokyo) 105, 883-887
41. 41 Yoshino, H., Minari, O., Matsushima, N., Ueki, T., Miyake, Y., Matsuo, T. and Izumi, Y. (1989) J. Biol. Chem. 264, 19706-19709
42. 42 Kataoka, M., Head, J. F., Seaton, B. A. and Engelman, D. M. (1989) Proc. Natl. Acad. Sci. U.S.A. 86, 6944-6948
43. 43 Knott, R., Hansen, S. and Henderson, S. (1994) J. Struct. Biol. 112, 192-198
44. 44 Yoshino, H., Wakita, M. and Izumi, Y. (1993) J. Biol. Chem. 268, 12123-12128
45. 45 Heidorn, D. B., Seeger, P. A., Rokop, S. E., Blumenthal, D. K., Means, A. R., Crespi, H. and Trewhella, J. (1989) Biochemistry 28, 6757-6764
46. 46 Trewhella, J., Blumenthal, D. K., Rokop, S. E. and Seeger, P. A. (1990) Biochemistry 29, 9316-9324
47. 47 Kataoka, M., Head, J. F., Vorherr, T., Krebs, J. and Carafoli, E. (1991) Biochemistry 30, 6247-6251
48. 48 Kleerekoper, Q., Liu, W. L., Choi, D. and Putkey, J. A. (1998) J. Biol. Chem. 273, 8153-8160
49. 49 Houdusse, A. and Cohen, C. (1995) Proc. Natl. Acad. Sci. U.S.A. 92, 10644-10647
50. 50 Swindells, M. B. and Ikura, M. (1996) Nat. Struct. Biol. 3, 501-504
51. 51 Nelson, M. R. and Chazin, W. J. (1998) Protein Sci. 7, 270-282
52. 52 Huang, W., Wilson, G. J., Brown, L. J., Lam, H. and Hambly, B. D. (1996) Eur. J. Biochem. 257, 457-465