Molecular organization, catalytic mechanism and function of serine hydroxymethyltransferase - A potential target for cancer chemotherapy

International Journal of Biochemistry and Cell Biology

Volumn 32, Issue 4, 2000, Pages 405-416

  Appaji Rao, N ^a   Talwar, Rashmi ^a   Savithri, H S ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Catalysis; Chemotherapeutic target; Drug design; Inhibitors; PLP; SHMT; X ray structure

Indexed keywords

AMINO ACID; GLYCINE HYDROXYMETHYLTRANSFERASE; SERINE;

AMINO ACID METABOLISM; CANCER CHEMOTHERAPY; CATALYSIS; CRYSTAL STRUCTURE; DRUG DESIGN; ENZYME ACTIVATION; HUMAN; NUCLEOTIDE METABOLISM; REVIEW; X RAY ANALYSIS;

ESCHERICHIA COLI; OVIS ARIES;

EID: 0034174531     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(99)00126-0     Document Type: Article

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