Inverse relationship of expression between GM3 and globo-series ganglioside in human renal cell carcinoma

Tohoku Journal of Experimental Medicine

Volumn 190, Issue 4, 2000, Pages 271-278

  Saito, Seiichi ^a   Nojiri, Hisao ^b   Satoh, Makoto ^a   Ito, Akihiro ^a   Ohyama, Chikara ^a   Orikasa, Seiichi ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

Brefeldin A; Globo series ganglioside; GM3; Renal cell carcinoma

Indexed keywords

BREFELDIN A; GANGLIOSIDE; GANGLIOSIDE GM3; GLOBOSIDE; PROTEIN SYNTHESIS INHIBITOR;

ARTICLE; CELL CULTURE; CELL DIVISION; DRUG EFFECT; HUMAN; KIDNEY CARCINOMA; KIDNEY TUMOR; METABOLISM; PATHOLOGY; PROGNOSIS;

BREFELDIN A; CARCINOMA, RENAL CELL; CELL DIVISION; G(M3) GANGLIOSIDE; GANGLIOSIDES; GLOBOSIDES; HUMANS; KIDNEY NEOPLASMS; PROGNOSIS; PROTEIN SYNTHESIS INHIBITORS; TUMOR CELLS, CULTURED;

EID: 0034170273     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.190.271     Document Type: Article

References (16)

1. Fenderson, B.A., Eddy, E.M. & Hakomori, S. (1990) Glycoconjugate expression during embryogenesis and its biological significance. Bioessays, 12, 173-179.
2. Goss, P. E., Baptiste, J., Fernandes, B., Baker, M. & Dennis, J. W. (1994) Phase I study of swainsonine in patients with advanced malignancies. Cancer Res., 54, 1450-1457.
3. Hakomori, S. (1996) Tumor malignancy defined by aberrant glycosylation and sphingo (glyco) lipid metabolism. Cancer Res., 56, 5309-5318.
4. 125I-labeled toxin to thin layer chromatograms. Anal. Biochem., 109, 399-402.
5. Mudlers, P., Figlin, R., deKernion, J.B., Wiltrout, R., Linehan, M., Parkinson, D., deWolf, W. & Belldegrun, A. (1997) Renal cell carcinoma: recent progress and future directions. Cancer Res., 57, 5189-5195.
6. Noda, I., Fujieda, S., Seki, M., Tanaka, N., Sunaga, H., Ohtsubo, T., Tsuzuki, H., Fan, G.K. & Saito, H. (1999) Inhibition of N-linked glycosylation by tunicamycin enhances sensitivity to cisplatin in human head-and-neck carcinoma cells. Int. J. Cancer, 80, 279-284.
7. Nojiri, H., Takaku, F., Terui, Y., Miura, Y. & Saito, M. (1986) Ganglioside GM3: An acidic membrane component that increases during macrophage-like cell differentiation can induce monocytic differentiation of human myeloid and monocytoid leukemic cell line HL-60 and U937. Proc. Natl. Acad. Sci. USA, 83, 782-786.
8. Nojiri, H., Manya, H., Isono, H., Yamana, H. & Nojima, S. (1999) Induction of terminal differentiation and apoptosis in human colonic carcinoma cells by brefeldin A, a drug affecting ganglioside biosynthesis. FEBS Lett., 453, 140-144.
9. Ono, M., Handa, K., Withers, D.A. & Hakomori, S. (1999) Motility inhibition and apoptosis are induced by metastasis-suppressing gene product CD82 and its analogue CD9, with concurrent glycosylation. Cancer Res., 59, 2335-2339.
10. Saito, S., Orikasa, S., Ohyama, C., Satoh, M. & Fukushi, Y. (1991) Changes in glycolipids in human renal-cell carcinoma and their clinical significance. Int. J. Cancer, 49, 329-334.
11. α2 → 6)GalNAc, presented by different carrier glycosylceramide or O-linked peptides, is recognized by different antibodies and ligands having distinct specificities. J. Biol. Chem., 269, 5644-5652.
12. Saito, S., Orikasa, S., Satoh, M., Ohyama, C., Ito, A. & Takahashi, T. (1997) Expression of globo-series gangliosides in human renal cell carcinoma. Jpn. J. Cancer Res., 88, 652-659.
13. Satoh, M., Handa, K., Saito, S., Tokuyama, S., Ito, A., Miyao, N., Orikasa, S. & Hakomori, S. (1996) Disialosyl galactosylgloboside as an adhesion molecule expressed on renal cell carcinoma and its relationship to metastatic potential. Cancer Res., 56, 1932-1938.
14. Satoh, M., Moosavi Nejad, F., Nakano, O., Ito, A., Kawamura, S., Ohyama, C., Saito, S. & Orikasa, S. (1999) Four new human renal cell carcinoma cell lines expressing globo-series gangliosides. Tohoku J. Exp. Med., 189, 95-105.
15. Sherwood, A.L. & Holmes, E.H. (1992) Brefeldin A induced inhibition of de novo globo- and neolacto-series glycolipid core chain biosynthesis in human cells. J. Biol. Chem., 267, 25328-25336.
16. Ulchalker, J.C. & Klein, E.A. (1996) Biology of metastasis and its clinical implications: renal-cell cancer. World J. Urol., 14, 175-181.