The structure and antimalarial activity of some cis-fused bicyclic 1,2,4-trioxane derivatives

Heterocycles

Volumn 49, Issue 1, 1998, Pages 375-383

  Jefford, Charles W ^a   Jaggi, Danielle ^a   Kohmoto, Shigeo ^a   Timári, Géza ^a   Bernardinelli, Gérald ^a   Canfield, Craig J ^b   Milhous, Wilbur K ^c  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Pharmaceutical Systems Inc   (United States)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4'A,5,6,7'A TETRAHYDRO 6',7'A BIS(4 FLUOROPHENYL) 5,6 EPI(N PHTHALIMIDOIMINO)SPIRO(CYCLOPENTANE 1,3' CYCLOPENTA[1,2 E][1,2,4]TRIOXINE); 4'A,7'A DIHYDRO 6',7'A BIS(4 FLUOROPHENYL) 5 (N PHTHALIMIDOAMINO)SPIRO(CYCLOPENTANE 1,3' 5'H CYCLOPENTA[1,2 E][1,2,4]TRIOXINE); 4A,5,6,7A TETRAHYDRO 3,3 DIMETHYL 5,6 EPI(DICHLOROMETHYLENE) 6,7A DIPHENYLCYCLOPENTA[1,2 E][1,2,4]TRIOXINE; 4A,7A DIHYDRO 3,3 DIMETHYL 6,7A DIPHENYL 7H CYCLOPENTA[1,2 E][1,2,4]TRIOXINE; 6',7'A BIS(4 FLUOROPHENYL) 4'A,7'A DIHYDROSPIRO[CYCLOPENTANE 1,3' 7'H CYCLOPENTA[1,2 E][1,2,4]TRIOXINE; ANTIMALARIAL AGENT; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; DIMERIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; MALARIA; PLASMODIUM FALCIPARUM; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

EID: 0032585374     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-98-s49     Document Type: Article

References (13)

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