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1
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0020552758
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Isolation and characterization of a mannan-binding protein from human serum
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Kawasaki N, Kawasaki T, Yamashina I. Isolation and characterization of a mannan-binding protein from human serum. J Biochem. 94:1983;937-947.
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Mannose-binding lectin: The pluripotent molecule of the innate immune system
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Turner MW. Mannose-binding lectin: the pluripotent molecule of the innate immune system. Immunol Today. 17:1996;532-540.
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Immunol Today
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Turner, M.W.1
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0023918065
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A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectins
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Ezekowitz RAB, Day L, Herman GA. A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectins. J Exp Med. 167:1988;1034-1046.
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Ezekowitz, R.A.B.1
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5
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0003225062
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MASP (MBP-associated serine protease)
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R.A.B. Ezekowitz, K. Sastry, K. Reid, B.M. Austin, Landes R.G.
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Matsushita M, Fujita T. MASP (MBP-associated serine protease). Ezekowitz RAB, Sastry K, Reid K, Austin BM, Landes RG. Collectins and Innate Immunity. 1996;165-182.
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Collectins and Innate Immunity
, pp. 165-182
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Matsushita, M.1
Fujita, T.2
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6
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0023645042
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Serum lectin with known structure activates complement through the classical pathway
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Ikeda K, Sannoh T, Kawasaki N, Kawasaki T, Yamashina I. Serum lectin with known structure activates complement through the classical pathway. J Biol Chem. 262:1987;7451-7454.
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(1987)
J Biol Chem
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Ikeda, K.1
Sannoh, T.2
Kawasaki, N.3
Kawasaki, T.4
Yamashina, I.5
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7
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0025145598
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The mechanism of carbohydrate-mediated complement activation by the serum mannan-binding protein
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Ohta M, Okada M, Yamashina I, Kawasaki T. The mechanism of carbohydrate-mediated complement activation by the serum mannan-binding protein. J Biol Chem. 265:1990;1980-1984.
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Ohta, M.1
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Kawasaki, T.4
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8
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0025230703
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2 complex, of the classical pathway of complement, without involvement of C1q
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2 complex, of the classical pathway of complement, without involvement of C1q. J Immunol. 144:1990;2287-2294.
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Lu, J.1
Thiel, S.2
Wiedemann, H.3
Timpl, R.4
Reid, K.B.M.5
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9
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0026445745
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Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease
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Matsushita M, Fujita T. Activation of the classical complement pathway by mannose-binding protein in association with a novel C1s-like serine protease. J Exp Med. 176:1992;1497-1502.
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J Exp Med
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Matsushita, M.1
Fujita, T.2
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10
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0030950185
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A second serine protease associated with mannan-binding lectin that activates complement
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of outstanding interest. This report demonstrates that human MBL is associated not only with the first described form of MBL-associated serine protease (MASP1) but also with a second serine protease termed MASP2. A striking structural similarity between MASP1 and MASP2, and the proteolytic activity of MASP2 are described.
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Thiel S, Vorup-Jensen T, Stover CM, Schwaeble W, Laursen SB, Poulsen K, Willis AC, Eggleton P, Hansen S, Holmskov U, et al. A second serine protease associated with mannan-binding lectin that activates complement. of outstanding interest Nature. 386:1997;506-510 This report demonstrates that human MBL is associated not only with the first described form of MBL-associated serine protease (MASP1) but also with a second serine protease termed MASP2. A striking structural similarity between MASP1 and MASP2, and the proteolytic activity of MASP2 are described.
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(1997)
Nature
, vol.386
, pp. 506-510
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Thiel, S.1
Vorup-Jensen, T.2
Stover, C.M.3
Schwaeble, W.4
Laursen, S.B.5
Poulsen, K.6
Willis, A.C.7
Eggleton, P.8
Hansen, S.9
Holmskov, U.10
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11
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0028343828
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Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein
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Sato T, Endo Y, Matsushita M, Fujita T. Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein. Int Immunol. 6:1994;665-669.
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(1994)
Int Immunol
, vol.6
, pp. 665-669
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Sato, T.1
Endo, Y.2
Matsushita, M.3
Fujita, T.4
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12
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0027378207
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A new member of the C1s family of complement protein found in a bactericidal factor, Ra-reactive factor, in human serum
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Takada F, Takayama H, Hatsuse H, Kawakami M. A new member of the C1s family of complement protein found in a bactericidal factor, Ra-reactive factor, in human serum. Biochem Biophys Res Commun. 196:1994;1003-1009.
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Biochem Biophys Res Commun
, vol.196
, pp. 1003-1009
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Takada, F.1
Takayama, H.2
Hatsuse, H.3
Kawakami, M.4
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13
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0029837728
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Exon structure of the gene encoding the human mannose-binding protein-associated serine protease (MASP) light chain: Comparison with complement C1r and C1s genes
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of outstanding interest. In this report, the authors demonstrated that the serime protease domain of human MASP1 is encoded by six exons, while those of C1r and C1s are encoded by a single exon. These results suggest that the MASP1 gene is a prototype form.
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Endo Y, Sato T, Matsushita M, Fujita T. Exon structure of the gene encoding the human mannose-binding protein-associated serine protease (MASP) light chain: comparison with complement C1r and C1s genes. of outstanding interest Int Immunol. 8:1996;1355-1358 In this report, the authors demonstrated that the serime protease domain of human MASP1 is encoded by six exons, while those of C1r and C1s are encoded by a single exon. These results suggest that the MASP1 gene is a prototype form.
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(1996)
Int Immunol
, vol.8
, pp. 1355-1358
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Endo, Y.1
Sato, T.2
Matsushita, M.3
Fujita, T.4
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14
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0021267206
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A group of bactericidal factors conserved by vertebrates for more than 300 million years
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Kawakami M, Ihara I, Ihara S, Suzuki A, Fukui K. A group of bactericidal factors conserved by vertebrates for more than 300 million years. J Immunol. 132:1984;2578-2581.
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J Immunol
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Kawakami, M.1
Ihara, I.2
Ihara, S.3
Suzuki, A.4
Fukui, K.5
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15
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0020041418
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A new complement dependent bactericidal factor found in nonimmune mouse sera: Specific binding to polysaccharide of Ra chemotype Salmonella
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Ihara I, Harada Y, Ihara S, Kawakami M. A new complement dependent bactericidal factor found in nonimmune mouse sera: specific binding to polysaccharide of Ra chemotype Salmonella. J Immunol. 128:1982;1256-1260.
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, vol.128
, pp. 1256-1260
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Ihara, I.1
Harada, Y.2
Ihara, S.3
Kawakami, M.4
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16
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0024231102
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The C4 and C2 but not C1 components of complement are responsible for the complement activation triggered by the Ra-reactive factor
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Ji Y-H, Matsushita M, Okada H, Fujita T, Kawakami M. The C4 and C2 but not C1 components of complement are responsible for the complement activation triggered by the Ra-reactive factor. J Immunol. 141:1988;4271-4275.
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J Immunol
, vol.141
, pp. 4271-4275
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Ji Y-H1
Matsushita, M.2
Okada, H.3
Fujita, T.4
Kawakami, M.5
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17
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0026524993
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Human mannose-binding protein is identical to a component of Ra-reactive factor
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Matsushita M, Takahashi A, Hatsuse H, Kawakami M, Fujita T. Human mannose-binding protein is identical to a component of Ra-reactive factor. Biochem Biophys Res Commun. 183:1992;645-651.
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Biochem Biophys Res Commun
, vol.183
, pp. 645-651
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Matsushita, M.1
Takahashi, A.2
Hatsuse, H.3
Kawakami, M.4
Fujita, T.5
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18
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0026700973
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CDNAs and deduced amino acid sequences of subunits in the binding component of mouse bactericidal factor, Ra-reactive factor: Similarity to mannose-binding proteins
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Kuge S, Ihara S, Watanabe E, Watanabe M, Takishima K, Suga T, Mamiya G, Kawakami M. cDNAs and deduced amino acid sequences of subunits in the binding component of mouse bactericidal factor, Ra-reactive factor: similarity to mannose-binding proteins. Biochemistry. 31:1992;6943-6950.
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(1992)
Biochemistry
, vol.31
, pp. 6943-6950
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Kuge, S.1
Ihara, S.2
Watanabe, E.3
Watanabe, M.4
Takishima, K.5
Suga, T.6
Mamiya, G.7
Kawakami, M.8
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19
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0027204626
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Activation of the C4 and C2 components of complement by a protease in serum bactericidal factor, Ra reactive factor
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Ji Y-H, Fujita T, Hatsuse H, Takahashi A, Matsushita M, Kawakami M. Activation of the C4 and C2 components of complement by a protease in serum bactericidal factor, Ra reactive factor. J Immunol. 150:1993;571-578.
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(1993)
J Immunol
, vol.150
, pp. 571-578
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Ji Y-H1
Fujita, T.2
Hatsuse, H.3
Takahashi, A.4
Matsushita, M.5
Kawakami, M.6
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20
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0028213533
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A 100-kDa protein in the C4-activating component of Ra-reactive factor is a new serine protease having module organization similar to C1r and C1s
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Takayama Y, Takada F, Takahashi A, Kawakami M. A 100-kDa protein in the C4-activating component of Ra-reactive factor is a new serine protease having module organization similar to C1r and C1s. J Immunol. 152:1994;2308-2316.
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J Immunol
, vol.152
, pp. 2308-2316
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Takayama, Y.1
Takada, F.2
Takahashi, A.3
Kawakami, M.4
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21
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0001473574
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Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian, Halocynthia roretzi
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of outstanding interest. This report describes the cDNA cloning of two types of MASP from tunicates. Their distinct proteolytic activities are also suggested from the amino-acid sequences of the serine protease domain.
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Ji X, Azumi K, Sasaki M, Nonaka M. Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian, Halocynthia roretzi. of outstanding interest Proc Natl Acad Sci USA. 94:1997;6340-6345 This report describes the cDNA cloning of two types of MASP from tunicates. Their distinct proteolytic activities are also suggested from the amino-acid sequences of the serine protease domain.
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(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6340-6345
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Ji, X.1
Azumi, K.2
Sasaki, M.3
Nonaka, M.4
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22
-
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0028805766
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Cleavage of the third component of complement (C3) by mannose-binding protein-associated serine protease (MASP) with subsequent complement activation
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Matsushita M, Fujita T. Cleavage of the third component of complement (C3) by mannose-binding protein-associated serine protease (MASP) with subsequent complement activation. Immunobiology. 194:1995;443-448.
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(1995)
Immunobiology
, vol.194
, pp. 443-448
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Matsushita, M.1
Fujita, T.2
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23
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0028971585
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The Gly→Asp allelic form of Human mannose-binding protein (MBP) fails to bind MBP-associated serine protease
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Matsushita M, Ezekowitz RAB, Fujita T. The Gly→Asp allelic form of Human mannose-binding protein (MBP) fails to bind MBP-associated serine protease. Biochem J. 311:1995;1021-1023.
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Biochem J
, vol.311
, pp. 1021-1023
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Matsushita, M.1
Ezekowitz, R.A.B.2
Fujita, T.3
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25
-
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0030831019
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Human serum mannose-binding lectin (MBL)-associated serine protease-1 (MASP-1): Determination of levels in body fluids and identification of two forms in serum
-
of outstanding interest. This is the first report on the determination of human serum MASP1 levels. The important findings were that MBL and MASP1 levels in serum are not correlated in the individual, and that MASP1 exists as MBL-bound and MBL-unbound forms.
-
Terai I, Kobayashi K, Matsushita M, Fujita T. Human serum mannose-binding lectin (MBL)-associated serine protease-1 (MASP-1): Determination of levels in body fluids and identification of two forms in serum. of outstanding interest Clin Exp Immunol. 110:1997;317-323 This is the first report on the determination of human serum MASP1 levels. The important findings were that MBL and MASP1 levels in serum are not correlated in the individual, and that MASP1 exists as MBL-bound and MBL-unbound forms.
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(1997)
Clin Exp Immunol
, vol.110
, pp. 317-323
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Terai, I.1
Kobayashi, K.2
Matsushita, M.3
Fujita, T.4
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26
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0028910256
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Substrate specificities of the protease of mouse serum Ra-reactive factor
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Ogata RT, Low PJ, Kawakami M. Substrate specificities of the protease of mouse serum Ra-reactive factor. J Immunol. 154:1995;2351-2357.
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(1995)
J Immunol
, vol.154
, pp. 2351-2357
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Ogata, R.T.1
Low, P.J.2
Kawakami, M.3
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27
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0030443077
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The lectin pathway of the complement system
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Matsushita M. The lectin pathway of the complement system. Microbiol Immunol. 40:1996;889-893.
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Microbiol Immunol
, vol.40
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Matsushita, M.1
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28
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0024458545
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A serum lectin (mannan-binding protein) has complement-dependent bactericidal activity
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Kawasaki N, Kawasaki T, Yamashina I. A serum lectin (mannan-binding protein) has complement-dependent bactericidal activity. J Biochem. 106:1989;483-489.
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(1989)
J Biochem
, vol.106
, pp. 483-489
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Kawasaki, N.1
Kawasaki, T.2
Yamashina, I.3
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29
-
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0024786545
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Human mannose-binding protein activates the alternative complement pathway and serum bactericidal activity on a mannose-rich isolate of Salmonella
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Schweinle JE, Ezekowitz RAB, Tenner AJ, Kuhlman M, Joiner KA: Human mannose-binding protein activates the alternative complement pathway and serum bactericidal activity on a mannose-rich isolate of Salmonella. J Clin Invest 84: 1821-1829.
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J Clin Invest
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, pp. 1821-1829
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Schweinle, J.E.1
Ezekowitz, R.A.B.2
Tenner, A.J.3
Kuhlman, M.4
Joiner, K.A.5
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30
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0028344851
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Complement-dependent neutralization of influenza virus by a serum mannose-binding lectin
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Anders EM, Hartley CA, Reading PC, Ezekowitz RAB. Complement-dependent neutralization of influenza virus by a serum mannose-binding lectin. J Gen Virol. 75:1994;615-622.
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Anders, E.M.1
Hartley, C.A.2
Reading, P.C.3
Ezekowitz, R.A.B.4
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31
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0028915759
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Mannose binding protein gene mutations associated with unusual and severe infections in adults
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Summerfield JA, Ryder S, Sumiya M, Thursz M, Gorchein A, Monteil MA, Turner MW. Mannose binding protein gene mutations associated with unusual and severe infections in adults. Lancet. 345:1995;886-889.
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Lancet
, vol.345
, pp. 886-889
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Summerfield, J.A.1
Ryder, S.2
Sumiya, M.3
Thursz, M.4
Gorchein, A.5
Monteil, M.A.6
Turner, M.W.7
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32
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0030986151
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Association of mutation in mannose-binding protein gene with childhood infection in consecutive hospital series
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Summerfield JA, Sumiya M, Levin M, Turner MW. Association of mutation in mannose-binding protein gene with childhood infection in consecutive hospital series. Brit Med J. 314:1997;1229-1232.
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Brit Med J
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, pp. 1229-1232
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Summerfield, J.A.1
Sumiya, M.2
Levin, M.3
Turner, M.W.4
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33
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0030599532
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Mutation of gene for manose-binding protein associated with chronic hepatitis B viral infection
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Thomas HC, Foster GR, Sumiya M, McIntosh D, Jack DL, Turner MW, Summerfield JA. Mutation of gene for manose-binding protein associated with chronic hepatitis B viral infection. Lancet. 348:1996;1417-1419.
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Lancet
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Thomas, H.C.1
Foster, G.R.2
Sumiya, M.3
McIntosh, D.4
Jack, D.L.5
Turner, M.W.6
Summerfield, J.A.7
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34
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0031027651
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Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin
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Garred P, Madsen HO, Balslev U, Hofmann B, Pedersen C, Gerstoft J, Svejgaard A. Susceptibility to HIV infection and progression of AIDS in relation to variant alleles of mannose-binding lectin. Lancet. 349:1997;236-240.
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Lancet
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, pp. 236-240
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Garred, P.1
Madsen, H.O.2
Balslev, U.3
Hofmann, B.4
Pedersen, C.5
Gerstoft, J.6
Svejgaard, A.7
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35
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0026920707
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Distinct and overlapping functions of allelic forms of human mannose-binding protein
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Super M, Gillies SD, Foler S, Sastry K, Schweinle JE, Silverman VJ, Ezekowitz RAB. Distinct and overlapping functions of allelic forms of human mannose-binding protein. Nature Genet. 2:1992;50-55.
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Nature Genet
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, pp. 50-55
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Super, M.1
Gillies, S.D.2
Foler, S.3
Sastry, K.4
Schweinle, J.E.5
Silverman, V.J.6
Ezekowitz, R.A.B.7
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36
-
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0028924063
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Mannose-binding protein recognizes glioma cells; In vitro analysis of complement activation on glioma cells via the lectin pathway
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Fujita T, Taira S, Kodama N, Matsushita M, Fujita T. Mannose-binding protein recognizes glioma cells; in vitro analysis of complement activation on glioma cells via the lectin pathway. Jpn J Cancer Res. 86:1995;187-192.
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Jpn J Cancer Res
, vol.86
, pp. 187-192
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Fujita, T.1
Taira, S.2
Kodama, N.3
Matsushita, M.4
Fujita, T.5
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37
-
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0028962403
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Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein
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Malhotra R, Wormald MR, Rudd PM, Fischer PB, Dwek RA, Sim RB. Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein. Nature Med. 1:1995;237-243.
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Nature Med
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, pp. 237-243
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Malhotra, R.1
Wormald, M.R.2
Rudd, P.M.3
Fischer, P.B.4
Dwek, R.A.5
Sim, R.B.6
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39
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0029360533
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Mannan-binding protein forms complexes with α-2-macroglobulin. A proposed model for the interation
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Storgaard P, Nielsen EH, Skriver E, Andersen O, Svehag S-H. Mannan-binding protein forms complexes with α-2-macroglobulin. A proposed model for the interation. Scand J Immunol. 42:1995;373-380.
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Scand J Immunol
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, pp. 373-380
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Storgaard, P.1
Nielsen, E.H.2
Skriver, E.3
Andersen, O.4
Svehag S-H5
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40
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0030028797
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Sea urchin genes expressed in activated coelomocytes are identified by expressed sequence tags
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of special interest. This is the first description of an invertebrate C3-like sequence, which was found in a cDNA library from sea urchin coelomocytes. This cDNA library contains sequences characteristic of complement control protein (short consensus repeat) domains that are found in a variety of proteins such as mammalian complement receptors. These findings suggest that sea urchins possess a simple phagocytosis system utilizing complement components.
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Smith LC, Chang L, Britten RJ, Davidson EH. Sea urchin genes expressed in activated coelomocytes are identified by expressed sequence tags. of special interest J Immunol. 156:1996;593-602 This is the first description of an invertebrate C3-like sequence, which was found in a cDNA library from sea urchin coelomocytes. This cDNA library contains sequences characteristic of complement control protein (short consensus repeat) domains that are found in a variety of proteins such as mammalian complement receptors. These findings suggest that sea urchins possess a simple phagocytosis system utilizing complement components.
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(1996)
J Immunol
, vol.156
, pp. 593-602
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-
Smith, L.C.1
Chang, L.2
Britten, R.J.3
Davidson, E.H.4
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41
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0026522052
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Complete complementary DNA sequence of the third component of complement of lamprey: Implication for the evolution of thioester containing proteins
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Nonaka M, Takahashi M. Complete complementary DNA sequence of the third component of complement of lamprey: implication for the evolution of thioester containing proteins. J Immunol. 148:1992;3290-3295.
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J Immunol
, vol.148
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Nonaka, M.1
Takahashi, M.2
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42
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0028220653
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Molecular cloning of a lamprey homologue of the mammalian MHC class III gene, complement factor B
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Nonaka M, Takahashi M, Sasaki M. Molecular cloning of a lamprey homologue of the mammalian MHC class III gene, complement factor B. J Immunol. 152:1994;2263-2269.
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(1994)
J Immunol
, vol.152
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Nonaka, M.1
Takahashi, M.2
Sasaki, M.3
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