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Volumn 11, Issue 2, 2000, Pages 61-66

Newer agents for hormonal contraception in the male

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; CYPROTERONE ACETATE; DESOGESTREL; GESTAGEN; GONADORELIN DERIVATIVE; LEVONORGESTREL; MEDROXYPROGESTERONE ACETATE; NANDROLONE DERIVATIVE; TESTOSTERONE; TESTOSTERONE ENANTATE; TESTOSTERONE UNDECANOATE;

EID: 0034159947     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-2760(99)00224-6     Document Type: Review
Times cited : (22)

References (37)
  • 2
    • 0029960780 scopus 로고    scopus 로고
    • Contraceptive efficacy of testosterone-induced azoospermia and oligozoospermia in normal men
    • World Health Organization Task Force on Methods for the Regulation of Male Fertility Contraceptive efficacy of testosterone-induced azoospermia and oligozoospermia in normal men. Fertil. Steril. 65:1996;821-829.
    • (1996) Fertil. Steril. , vol.65 , pp. 821-829
  • 3
    • 0028851197 scopus 로고
    • Factors in nonuniform induction of azoospermia by testosterone enanthate in normal men
    • Handelsman D.J.et al. Factors in nonuniform induction of azoospermia by testosterone enanthate in normal men. Fertil. Steril. 63:1995;125-133.
    • (1995) Fertil. Steril. , vol.63 , pp. 125-133
    • Handelsman, D.J.1
  • 4
  • 5
    • 0001163993 scopus 로고
    • Contraceptive efficacy of testosterone-induced azoospermia in normal men
    • World Health Organization Contraceptive efficacy of testosterone-induced azoospermia in normal men. Lancet. 336:1990;995-999.
    • (1990) Lancet , vol.336 , pp. 995-999
  • 6
    • 84995851420 scopus 로고
    • Metabolic and behavioral effects of high-dose, exogenous testosterone in healthy men
    • Bagatell C.J.et al. Metabolic and behavioral effects of high-dose, exogenous testosterone in healthy men. J. Clin. Endocrinol. Metab. 79:1994;561-567.
    • (1994) J. Clin. Endocrinol. Metab. , vol.79 , pp. 561-567
    • Bagatell, C.J.1
  • 7
    • 0028785750 scopus 로고
    • Testosterone enanthate at the dose 200 mg/week decreases HDL-cholesterol levels in healthy men
    • Meriggiola M.C.et al. Testosterone enanthate at the dose 200 mg/week decreases HDL-cholesterol levels in healthy men. Int. J. Androl. 18:1995;237-242.
    • (1995) Int. J. Androl. , vol.18 , pp. 237-242
    • Meriggiola, M.C.1
  • 8
    • 0026497649 scopus 로고
    • Testosterone buciclate (20 Aet-1) in hypogonadal men: Pharmacokinetics and pharmacodynamics of the new long-acting androgen ester
    • Behre H.M., Nieschlag E. Testosterone buciclate (20 Aet-1) in hypogonadal men: pharmacokinetics and pharmacodynamics of the new long-acting androgen ester. J. Clin. Endocrinol. Metab. 75:1992;1204-1210.
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , pp. 1204-1210
    • Behre, H.M.1    Nieschlag, E.2
  • 9
    • 0016749625 scopus 로고
    • The pharmacology and metabolism of testosterone undecanoate (TU), a new orally active androgen
    • Coert A.et al. The pharmacology and metabolism of testosterone undecanoate (TU), a new orally active androgen. Acta Endocrinol. 79:1975;789-800.
    • (1975) Acta Endocrinol. , vol.79 , pp. 789-800
    • Coert, A.1
  • 10
    • 0032422573 scopus 로고    scopus 로고
    • A pharmacokinetic study of injectable testosterone undecanoate in hypogonadal men
    • Zhang G.Y.et al. A pharmacokinetic study of injectable testosterone undecanoate in hypogonadal men. J. Androl. 19:1998;761-768.
    • (1998) J. Androl. , vol.19 , pp. 761-768
    • Zhang, G.Y.1
  • 11
    • 0033014486 scopus 로고    scopus 로고
    • Intramuscular injection of testosterone undecanoate for the treatment of male hypogonadism: Phase I studies
    • Behre A.M.et al. Intramuscular injection of testosterone undecanoate for the treatment of male hypogonadism: phase I studies. Eur. J. Endrocrinol. 140:1999;414-419.
    • (1999) Eur. J. Endrocrinol. , vol.140 , pp. 414-419
    • Behre, A.M.1
  • 12
    • 0033304546 scopus 로고    scopus 로고
    • Injectable testosterone undecanoate for contraception in Chinese men
    • Zhang G.Y.et al. Injectable testosterone undecanoate for contraception in Chinese men. J. Clin. Endocrinol. Metab. 84:1999;3642-3647.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 3642-3647
    • Zhang, G.Y.1
  • 13
    • 0021329587 scopus 로고
    • Reversible azoospermia induced by the anabolic steroid 19-nortestosterone
    • Schurmeyer T.et al. Reversible azoospermia induced by the anabolic steroid 19-nortestosterone. Lancet. 25:1984;417-420.
    • (1984) Lancet , vol.25 , pp. 417-420
    • Schurmeyer, T.1
  • 14
    • 0027369185 scopus 로고
    • Comparison of two androgens plus depot-medroxyprogesterone acetate for suppression to azoospermia in Indonesian men
    • World Health Organization Comparison of two androgens plus depot-medroxyprogesterone acetate for suppression to azoospermia in Indonesian men. Fertil. Steril. 60:1993;1062-1068.
    • (1993) Fertil. Steril. , vol.60 , pp. 1062-1068
  • 15
    • 0027931347 scopus 로고
    • 7-Alpha-methyl-19-nortestosterone: An ideal androgen for replacement therapy
    • Sundaram K.et al. 7-alpha-methyl-19-nortestosterone: an ideal androgen for replacement therapy. Recent Prog. Horm. Res. 49:1994;373-376.
    • (1994) Recent Prog. Horm. Res. , vol.49 , pp. 373-376
    • Sundaram, K.1
  • 16
    • 0029862979 scopus 로고    scopus 로고
    • Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. III. Higher 5α-reductase activity in oligospermic men administered supraphysiological doses of testosterone
    • Anderson R.et al. Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. III. Higher 5α-reductase activity in oligospermic men administered supraphysiological doses of testosterone. J. Clin. Endocrinol. Metab. 81:1996;902-908.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 902-908
    • Anderson, R.1
  • 17
    • 3042866315 scopus 로고    scopus 로고
    • Prostate-sparing tissue specific effects of the potent androgen 7α-methyl-19-nortestosterone (MENT) in primates
    • Cummings D.E.et al. Prostate-sparing tissue specific effects of the potent androgen 7α-methyl-19-nortestosterone (MENT) in primates. J. Clin. Endocrinol. Metab. 83:1998;4212-4219.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 4212-4219
    • Cummings, D.E.1
  • 18
    • 0033323816 scopus 로고    scopus 로고
    • Clinical trial of transdermal testosterone and oral levonorgestrel for male contraception
    • Buchter D.et al. Clinical trial of transdermal testosterone and oral levonorgestrel for male contraception. J. Clin. Endocrinol. Metab. 84:1999;1244-1249.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 1244-1249
    • Buchter, D.1
  • 19
    • 0032906159 scopus 로고    scopus 로고
    • Discovery of a potent, orally active, nonsteroidal androgen receptor agonist: 4-ethyl-1,2,3,4-tetrahydro-6-(trifluoromethyl)-8-pyri-dono[5,6-g]-quinoline (LG121071)
    • Hamann L.G.et al. Discovery of a potent, orally active, nonsteroidal androgen receptor agonist: 4-ethyl-1,2,3,4-tetrahydro-6-(trifluoromethyl)-8-pyri-dono[5,6-g]-quinoline (LG121071). J. Med. Chem. 42:1999;210-212.
    • (1999) J. Med. Chem. , vol.42 , pp. 210-212
    • Hamann, L.G.1
  • 20
    • 0025751705 scopus 로고
    • Combined administration of a gonadotropin-releasing hormone antagonist and testosterone in men induces reversible azoospermia without loss of libido
    • Pavlou S.N.et al. Combined administration of a gonadotropin-releasing hormone antagonist and testosterone in men induces reversible azoospermia without loss of libido. J. Clin. Endocrinol. Metab. 73:1991;1360-1369.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 1360-1369
    • Pavlou, S.N.1
  • 21
    • 0026688067 scopus 로고
    • Induction of azoospermia in normal men with combined Nal-Glu gonadotropin-releasing hormone and testosterone enanthate
    • Tom L.et al. Induction of azoospermia in normal men with combined Nal-Glu gonadotropin-releasing hormone and testosterone enanthate. J. Clin Endocrinol. Metab. 75:1992;476-483.
    • (1992) J. Clin Endocrinol. Metab. , vol.75 , pp. 476-483
    • Tom, L.1
  • 22
    • 0027250374 scopus 로고
    • Comparison of a gonadotropin releasing-hormone antagonist plus testosterone (T) versus T alone as potential male contraceptive regimens
    • Bagatell C.J.et al. Comparison of a gonadotropin releasing-hormone antagonist plus testosterone (T) versus T alone as potential male contraceptive regimens. J. Clin. Endocrinol. Metab. 77:1993;427-432.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 427-432
    • Bagatell, C.J.1
  • 23
    • 0031741889 scopus 로고    scopus 로고
    • Suppression of spermatogenesis in man induced by Nal-Glu gonadotropin releasing hormone antagonist and testosterone enanthate (TE) is maintained by TE alone
    • Swerdloff R.S.et al. Suppression of spermatogenesis in man induced by Nal-Glu gonadotropin releasing hormone antagonist and testosterone enanthate (TE) is maintained by TE alone. J. Clin. Endocrinol. Metab. 83:1998;3527-3533.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 3527-3533
    • Swerdloff, R.S.1
  • 24
    • 0033062355 scopus 로고    scopus 로고
    • Effect of acute androgen withdrawal by GnRH antagonist on epididymal sperm motility and morphology in the cynomolgus monkey
    • Yeung C.H.et al. Effect of acute androgen withdrawal by GnRH antagonist on epididymal sperm motility and morphology in the cynomolgus monkey. J. Androl. 20:1999;72-79.
    • (1999) J. Androl. , vol.20 , pp. 72-79
    • Yeung, C.H.1
  • 25
    • 0033031289 scopus 로고    scopus 로고
    • Pharmacokinetics of new testosterone transdermal therapeutic systems in gonadotropin-releasing hormone antagonist-suppressed normal men
    • Rolf C.et al. Pharmacokinetics of new testosterone transdermal therapeutic systems in gonadotropin-releasing hormone antagonist-suppressed normal men. Exp. Clin. Endocrinol. Diabetes. 107:1999;63-69.
    • (1999) Exp. Clin. Endocrinol. Diabetes , vol.107 , pp. 63-69
    • Rolf, C.1
  • 26
    • 15444355594 scopus 로고    scopus 로고
    • Discovery of a novel, potent and orally active nonpeptide antagonist of the human luteinizing hormone-releasing hormone (LHRH) receptor
    • Cho N.et al. Discovery of a novel, potent and orally active nonpeptide antagonist of the human luteinizing hormone-releasing hormone (LHRH) receptor. J. Med. Chem. 41:1998;4190-4195.
    • (1998) J. Med. Chem. , vol.41 , pp. 4190-4195
    • Cho, N.1
  • 27
    • 0018079789 scopus 로고
    • Hormonal contraception for men
    • Schearer S.B.et al. Hormonal contraception for men. Int. J. Androl. 2:1978;680-695.
    • (1978) Int. J. Androl. , vol.2 , pp. 680-695
    • Schearer, S.B.1
  • 28
    • 0015469795 scopus 로고
    • Effect of low doses of synthetic progestogens on testicular function
    • Fotherby K.et al. Effect of low doses of synthetic progestogens on testicular function. Int. J. Fertil. 17:1972;113-119.
    • (1972) Int. J. Fertil. , vol.17 , pp. 113-119
    • Fotherby, K.1
  • 29
    • 0030917993 scopus 로고    scopus 로고
    • Progestin-androgen combination regimens for male contraception
    • Meriggiola M.C., Bremner W.J. Progestin-androgen combination regimens for male contraception. J. Androl. 18:1997;240-244.
    • (1997) J. Androl. , vol.18 , pp. 240-244
    • Meriggiola, M.C.1    Bremner, W.J.2
  • 30
    • 0018305575 scopus 로고
    • Pregnancies associated with sperm concentrations below 10 million/ml in clinical studies of a potential male contraceptive method, monthly depot medroxyprogesterone acetate and testosterone esters
    • Barfield A.et al. Pregnancies associated with sperm concentrations below 10 million/ml in clinical studies of a potential male contraceptive method, monthly depot medroxyprogesterone acetate and testosterone esters. Contraception. 20:1977;121-127.
    • (1977) Contraception , vol.20 , pp. 121-127
    • Barfield, A.1
  • 31
    • 0030050344 scopus 로고    scopus 로고
    • Combined administration of levonorgestrel and testosterone induces more rapid and effective suppression of spermatogenesis than testosterone alone: A promising male contraceptive approach
    • Bebb R.A.et al. Combined administration of levonorgestrel and testosterone induces more rapid and effective suppression of spermatogenesis than testosterone alone: a promising male contraceptive approach. J. Clin. Endocrinol. Metab. 81:1996;757-762.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 757-762
    • Bebb, R.A.1
  • 32
    • 0033001262 scopus 로고    scopus 로고
    • A lower dosage levonorgestrel and testosterone combination effectively suppresses spermatogenesis and circulating gonadotropin levels with fewer metabolic effects than higher dosage combinations
    • Anawalt B.D.et al. A lower dosage levonorgestrel and testosterone combination effectively suppresses spermatogenesis and circulating gonadotropin levels with fewer metabolic effects than higher dosage combinations. J. Androl. 20:1999;407-414.
    • (1999) J. Androl. , vol.20 , pp. 407-414
    • Anawalt, B.D.1
  • 33
    • 0032902148 scopus 로고    scopus 로고
    • Oral progestogen combined with testosterone as a potential male contraceptive: Additive effects between desogestrel and testosterone enanthate in suppression of spermatogenesis, pituitary-testicular axis, and lipid metabolism
    • Wu F.C.et al. Oral progestogen combined with testosterone as a potential male contraceptive: additive effects between desogestrel and testosterone enanthate in suppression of spermatogenesis, pituitary-testicular axis, and lipid metabolism. J. Clin. Endocrinol. Metab. 84:1999;112-122.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 112-122
    • Wu, F.C.1
  • 34
  • 35
    • 0029811817 scopus 로고    scopus 로고
    • A combined regimen of cyproterone acetate and testosterone enanthate as a potentially highly effective male contraceptive
    • Meriggiola M.C.et al. A combined regimen of cyproterone acetate and testosterone enanthate as a potentially highly effective male contraceptive. J. Clin. Endocrinol. Metab. 81:1996;3018-3023.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 3018-3023
    • Meriggiola, M.C.1
  • 36
    • 2642647058 scopus 로고    scopus 로고
    • Low dose of cyproterone acetate and testosterone enanthate for contraception in men
    • Meriggiola M.C.et al. Low dose of cyproterone acetate and testosterone enanthate for contraception in men. Hum. Reprod. 13:1998;1225-1229.
    • (1998) Hum. Reprod. , vol.13 , pp. 1225-1229
    • Meriggiola, M.C.1
  • 37
    • 0342460485 scopus 로고    scopus 로고
    • An oral regimen of cyproterone acetate and testosterone for spermatogenic suppression in men
    • Meriggiola M.et al. An oral regimen of cyproterone acetate and testosterone for spermatogenic suppression in men. Fertil. Steril. 68:1997;844-850.
    • (1997) Fertil. Steril. , vol.68 , pp. 844-850
    • Meriggiola, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.