Effects of cytosine methylation on pyrimidine dimer formation in DNA

Photochemistry and Photobiology

Volumn 71, Issue 2, 2000, Pages 162-165

  Mitchell, David L ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLCYTOSINE; ADENOSINE DERIVATIVE; CYCLOBUTANE; CYTIDINE DERIVATIVE; CYTOSINE; DEOXYADENOSINE PHOSPHATE HOMOPOLYMER; DIMER; DNA; GUANOSINE DERIVATIVE; POLYDEOXY 5 METHYLCYTIDINE; POLYDEOXYCYTIDINE; POLYDEOXYGUANOSINE; POLYDEOXYTHYMIDINE; PYRIMIDINE; PYRIMIDINONE DERIVATIVE; THYMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DIMERIZATION; IRRADIATION; LIGHT; METHYLATION; MUTATION; SKIN CANCER; SPECTRUM; SUNLIGHT; ULTRAVIOLET B RADIATION; ULTRAVIOLET C RADIATION;

CYTOSINE; DNA; DNA METHYLATION; POLYDEOXYRIBONUCLEOTIDES; PYRIMIDINE DIMERS; ULTRAVIOLET RAYS;

EID: 0034143190     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/0031-8655(2000)071<0162:EOCMOP>2.0.CO;2     Document Type: Article

References (25)

1. Jonason, A. S., S. Kunala, G. J. Price, R. J. Restifo, H. M. Spinelli, J. A. Persing, D. J. Leffell, R. E. Tarone and D. E. Brash (1996) Frequent clones of p53-mutated keratinocytes in normal human skin. Proc. Natl. Acad. Sci. USA 93, 14025-14029.
2. Brash, D. E., J. A. Rudolph, J. A. Simon, A. Lin, G. J. Mc Kenna, H. P. Baden, A. J. Halperin and J. Ponten (1991) A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc. Natl. Acad. Sci. USA 88, 10124-10128.
3. Ananthaswamy, H. N. and W. E. Pierceall (1990) Molecular mechanisms of ultraviolet radiation carcinogenesis. Photochem. Photobiot. 52, 1119-1136.
4. Jones, P. A., J. D. Buckley, B. E. Henderson, R. K. Ross and M. C. Pike (1991) From gene to carcinogen: a rapidly evolving field in molecular epidemiology. Cancer Res. 51, 3617-3620.
5. Pfeifer, G. P. and G. P. Holmquist (1997) Mutagenesis in the P53 gene. Biochim. Biophys. Acta 1333, M1-M8.
6. Rideout, W. M., III, G. A. Coetzee, A. F. Olumni and P. A. Jones (1990) 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 249, 1288-1290.
7. Tornaletti, S. and G. P. Pfeifer (1995) Complete and tissueindependent methylation of CpG sites in the p53 gene: implications for mutations in human cancers. Oncogene 10, 1493-1499.
8. Drouin, R. and J.-P. Therrien (1997) UVB-induced cyclobutane dimer frequency correlates with skin cancer mutational hotspots in p53. Photochem. Photobiol. 66 719-726.
9. Neddermann, P., P. Gallinari, T. Lettiere, D. Schmid, O. Truong, J. J. Hsuan, K. Wiebauer and J. Jiricny (1996) Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase. J. Biol. Chem. 271, 12767-12774.
10. Tommasi, S., M. F. Denissenko and G. P. Pfeifer (1997) Sunlight induces pyrimidine dimers preferentially at 5-methylcytosine bases. Cancer Res. 57, 4727-4730.
11. Ehrlich, M. and M.-F. Dove (1983) Photolysis at 254 nm of 5methyldeoxycytidine. Photobiochem. Photobiophys. 6, 121-126.
12. Ehrlich, M., M.-F. Dove and L.-H. Huang (1986) Photolysis of methylated DNA. Photobiochem. Photobiophys. 11, 73-79.
13. Franklin, W. A., K. M. Lo and W. A. Haseltine (1982) Alkaline lability of fluorescent photoproducts produced in ultraviolet light-irradiated DNA. J. Biol. Chem. 257, 13535-13543.
14. Blais, J., T. Douki, P. Vigny and J. Cadet (1994) Fluorescence quantum yield determinations of pyrimidine(6-4)pyrimidone photoproducts. Photochem. Photobiol. 59, 402-404.
15. Douki, T. and J. Cadet (1994) Formation of cyclobutane dimers and (6-4)photoproducts upon far-UV photolysis of 5-methylcytosine-containing dinucleoside monophosphates. Biochemistry 33, 11942-11950.
16. Rosenstein, B. S. and D. L. Mitchell (1987) Action spectra for the induction of pyrimidine(6-4)pyrimidone photoproducts and cyclobutane pyrimidine dimers in normal human skin fibroblasts. Photochem. Photobiol. 45, 775-781.
17. Mitchell, D. L. (1996) Radioimmunoassay of DNA damaged by ultraviolet light. In Technologies for Detection of DNA Damage and Mutations (Edited by G. Pfeifer), pp. 73-85. Plenum Publishing Corp., New York.
18. Mitchell, D. L. (1999) Quantification of DNA photoproducts in mammalian cell DNA using radioimmunoassay. In Methods in Molecular Biology, DNA Repair Protocols (Edited by D. S. Henderson), pp. 165-174. The Humana Press Inc., Totowa, NJ.
19. Mitchell, D. L., J. Jen and J. E. Cleaver (1991) Sequence specificity of cyclobutane pyrimidine dimers in DNA treated with solar (ultraviolet B) radiation. Nucleic Acids Res. 20, 225-229.
20. Mitchell, D. L. and J. M. Clarkson (1984) Use of synthetic polynucleotides to characterize an antiserum made against UV-irradiated DNA. Photochem. Photobiol. 40, 743-748.
21. ntracts as revealed by cyclobutane thymine-thymine dimer formation. Nucleic Acids Res. 19, 4491-4496.
22. Lemaire, D. G. E. and B. P. Ruzsicksa (1993) Kinetic analysis of the deamination reactions of cyclobutane dimers of thymidylyl-3′-5′-2′-deoxycytidine and 2′-deoxycytidylyl-3′-5′-thymidine. Biochemistry 32, 2525-2533.
23. Cadet, J. and P. Vigny (1990) The photochemistry of nucleic acids. In Bioorganic Photochemistry, Vol. 1 (Edited by H. Morrison), pp. 1-272. Wiley, New York.
24. Sarma, M. H., G. Gupta and R. H. Sarma (1986) 500-MHz NMR study of poly(dG): poly(dC) in solution using one-dimensional nuclear Overhauser effect. Biochemistry 25, 3659-3665.
25. Gao, Y.-G., H. Robinson and A. H. J. Wang (1999) High-resolution A-DNA crystal structures of d(AGGGGCCCCT): an ADNA model of poly(dG): poly(dC). Eur. J. Biochem. 261, 413-420.