A recurrent RNA-binding domain is appended to eukaryotic aminoacyl-tRNA synthetases

EMBO Journal

Volumn 19, Issue 3, 2000, Pages 445-452

  Cahuzac, Bertrand ^a   Berthonneau, Eric ^b   Birlirakis, Nicolas ^a   Guittet, Eric ^a   Mirande, Marc ^b  

^a INSTITUT DE CHIMIE DES SUBSTANCES NATURELLES   (France)

^b CNRS   (France)

Author keywords

NMR spectroscopy; Protein RNA interactions; RNA binding domain; tRNA synthetase

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; ARGININE; LYSINE; POLYPEPTIDE; RNA BINDING PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CONSENSUS SEQUENCE; CONTROLLED STUDY; ENZYME STRUCTURE; EUKARYOTE; HUMAN; HUMAN CELL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING;

ANIMALIA; EUKARYOTA; PROKARYOTA;

EID: 0034141480     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.3.445     Document Type: Article

References (36)

1. Alzhanova, A.T., Fedorov, A.N., Ovchinnikov, L.P. and Spirin, A.S. (1980) Eukaryotic aminoacyl-tRNA synthetases are RNA binding proteins whereas prokaryotic ones are not. FEBS Lett., 120, 225-229.
2. Arnez, J.G. and Cavarelli, J. (1997) Structures of RNA-binding proteins. Q. Rev. Biophys., 30, 195-240.
3. Berglund, H., Rak, A., Serganov, A., Garber, M. and Härd, T. (1997) Solution structure of the ribosomal RNA binding protein S15 from Thermus thermophilus. Nature Struct. Biol., 4, 20-23.
4. Ser. Science, 263, 1404-1410.
5. Brünger, A.T. (1993) X-PLOR Version 3.1: A System for X-ray Crystallography and NMR. Yale University Press, New Haven, CT.
6. Cerini, C., Kerjan, P., Astier, M., Gratecos, D., Mirande, M. and Semeriva, M. (1991) A component of the multisynthetase complex is a multifunctional aminoacyl-tRNA synthetase. EMBO J., 10, 4267-4277.
7. Cerini, C., Semeriva, M. and Gratecos, D. (1997) Evolution of the aminoacyl-tRNA synthetase family and the organization of the Drosophila glutamyl-prolyl-tRNA synthetase gene. Eur. J. Biochem., 244, 176-185.
8. Chien, C.Y., Tejero, R., Huang, Y., Zimmerman, D.E., Rios, C.B., Krug, R.M. and Montelione, G.T. (1997) A novel RNA-binding motif in influenza A virus non-structural protein 1. Nature Struct. Biol., 4, 891-895.
9. Clemons, W.M., Jr, Davies, C., White, S.W. and Ramakrishnan, V. (1998) Conformational variability of the N-terminal helix in the structure of ribosomal protein S15. Structure, 6, 429-438.
10. Fett, R. and Knippers, R. (1991) The primary structure of human glutaminyl-tRNA synthetase. A highly conserved core, amino acid repeat regions and homologies with translation elongation factors. J. Biol. Chem., 266, 1448-1455.
11. Güntert, P. and Wüthrich, K. (1991) Improved efficiency of protein structure calculations from NMR data using the program DIANA with redundant dihedral angle constraints. J. Biomol. NMR, 1, 447-456.
12. Güntert, P., Braun, W. and Wüthrich, K. (1991) Efficient computation of three-dimensional protein structures in solution from nuclear magnetic resonance data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA. J. Mol. Biol., 217, 517-530.
13. Kerjan, P., Triconnet, M. and Waller, J.P. (1992) Mammalian prolyl-tRNA synthetase corresponds to the 150 kDa subunit of the high-Mr aminoacyl-tRNA synthetase complex. Biochimie, 74, 195-205.
14. Kleeman, T.A., Wei, D.B., Simpson, K.L. and First, E.A. (1997) Human tyrosyl tRNA synthetase shares amino acid sequence homology with a putative cytokine. J. Biol. Chem., 272, 14420-14425.
15. Liu, J., Lynch, P.A., Chien, C.Y., Montelione, G.T., Krug, R.M. and Berman, H.M. (1997) Crystal structure of the unique RNA-hinding domain of the influenza virus NS1 protein. Nature Struct. Biol., 4, 896-899.
16. Mirande, M. ( 1991 ) Aminoacyl-tRNA synthetase family from prokaryotes and eukaryotes: structural domains and their implications. Prog. Nucleic Acid Res. Mol. Biol., 40, 95-142.
17. Morales, A.J., Swairjo, M.A. and Schimmel, P. (1999) Structure-specific tRNA-binding protein from the extreme thermophile Aquifex aeolicus. EMBO J., 18, 3475-3483.
18. Negrutskii, B.S. and Deutscher, M.P. (1991) Channeling of aminoacyl-tRNA for protein synthesis in vivo. Proc. Natl Acad. Sci. USA, 88, 4991-4995.
19. Nicholls, A., Sharp, K.A. and Honig, B. (1991) Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins, 11, 281-296.
20. Park, S.G., Jung, K.H., Lee, J.S., Jo, Y.J., Motegi, H., Kim, S. and Shiba, K. (1999) Precursor of pro-apoptotic cytokine modulates aminoacylation activity of tRNA synthetase. J. Biol. Chem., 274, 16673-16676.
21. Piotto, M., Saudek, V. and Sklenar, V. (1992) Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions. J. Biomol. NMR, 2, 661-665.
22. Pons, J.L., Malliavin, T.E. and Delsuc, M.A. (1996) Gifa V.4: a complete package for NMR data set processing. J. Biomol. NMR, 8, 445-452.
23. Quevillon, S., Agou, F., Robinson, J.C. and Mirande, M. (1997) The p43 component of the mammalian multi-synthetase complex is likely to be the precursor of the endothelial monocyte-activating polypeptide II cytokine. J. Biol. Chem., 272, 32573-32579.
24. Raben, N., Nichols, R., Dohlman, J., McPhie, P., Sridhar, V., Hyde, C., Leff, R. and Plotz, P. (1994) A motif in human histidyl-tRNA synthetase which is shared among several aminoacyl-tRNA synthetases is a coiled-coil that is essential for enzymatic activity and contains the major autoantigenic epitope. J. Biol. Chem., 269, 24277-24283.
25. Rho, S.B., Lee, J.S., Jeong, E.J., Kim, K.S., Kim, Y.G. and Kim, S. (1998) A multifunctional repeated motif is present in human bifunctional tRNA synthetase. J. Biol. Chem., 273, 11267-11273.
26. Schimmel, P. and Söll, D. (1979) Aminoacyl-tRNA synthetases: general features and recognition of transfer RNAs. Annu. Rev. Biochem., 48, 601-648.
27. Simos, G., Sauer, A., Fasiolo, F. and Hurt, E.C. (1998) A conserved domain within Arclp delivers tRNA to aminoacyl-tRNA synthetases. Mol. Cell, 1, 235-242.
28. Stapulionis, R. and Deutscher, M.P. (1995) A channeled tRNA cycle during mammalian protein synthesis. Proc. Natl Acad. Sci. USA, 92, 7158-7161.
29. Pro. Biochemistry, 37, 8605-8613.
30. Ting, S.M., Bogner, P. and Dignam, J.D. (1992) Isolation of prolyl-tRNA synthetase as a free form and as a form associated with glutamyl-tRNA synthetase. J. Biol. Chem., 267, 17701-17709.
31. 15N-enriched proteins. J. Am. Chem. Soc., 115, 7772-7777.
32. Wakasugi, K. and Schimmel, P. (1999) Two distinct cytokines released from a human aminoacyl-tRNA synthetase. Science, 284, 147-151.
33. Wang, C.C. and Schimmel, P. (1999) Species barrier to RNA recognition overcome with nonspecific RNA binding domains. J. Biol. Chem., 274, 16508-16512.
34. Whelihan, E.F. and Schimmel, P. (1997) Rescuing an essential enzyme RNA complex with a non-essential appended domain. EMBO J., 16, 2968-2974.
35. Wu, H., Nada, S. and Dignam, J.D. (1995) Analysis of truncated forms of Bombyx mori glycyl-tRNA synthetase: function of an N-terminal structure in RNA binding. Biochemistry, 34, 16327-16336.
36. Yang, A.S., Hitz, B. and Honig, B. (1996) Free energy determinants of secondary structure formation: III. β-turns and their role in protein folding. J. Mol. Biol., 259, 873-882.