Studies on the 1,1-Diphenyl-2-picrylhydrazyl Radical Scavenging Mechanism for a 2-Pyrone Compound

Bioscience, Biotechnology and Biochemistry

Volumn 64, Issue 2, 2000, Pages 306-313

  Abe, Naoki ^a   Nemoto, Aya ^a   Tsuchiya, Yukiko ^a   Hojo, Hiroshi ^a   Hirota, Akira ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

1,1 diphenyl 2 picrylhydrazyl; 2 pyrone; Radical scavenger; Radical scavenging mechanism

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; 4 HYDROXY 3,6 DIMETHYL 2H PYRAN 2 ONE; 4-HYDROXY-3,6-DIMETHYL-2H-PYRAN-2-ONE; BEPRIDIL; DRUG DERIVATIVE; PICRIC ACID; PYRONE DERIVATIVE; SCAVENGER;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; KINETICS; SPECTROSCOPY;

BEPRIDIL; FREE RADICAL SCAVENGERS; KINETICS; MOLECULAR STRUCTURE; PICRATES; PYRONES; SPECTRUM ANALYSIS;

EID: 0034132309     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.64.306     Document Type: Article

References (11)

1. Morimitsu, Y. and Hirota, A., Ansamycin antibiotics as free radical scavengers isolated from Strep-tomyces by using the bactericidal action of the hydroxyl radical. Biosci. Biotechnol. Biochem., 60, 1507-1509 (1996).
2. Morimitsu, Y. and Hirota, A., Two oxazolyl compounds and a monosubstituted a-pyrone as free-radical scavengers isolated from a fungus. Biosci. Biotechnol. Biochem., 61, 1428-1433 (1997).
3. Blois, M. S., Antioxidant determinations by the use of a stable free radical. Nature, 181, 1199-1200 (1958).
4. Abe, N., Murata, T., and Hirota, A., Novel DPPH radical scavengers, bisorbicillinol and de-methyltrichodimerol, from a fungus. Biosci. Biotechnol. Biochem., 62, 661-666 (1998).
5. Abe, N., Murata, T., and Hirota, A., Novel oxidized sorbicillin dimers with l, l-diphenyl-2-pycryl-hydrazyl-radical scavenging activity from a fungus. Biosci. Biotechnol. Biochem., 62, 2120-2126 (1998).
6. Abe, N., Murata, T., Yamamoto, K., and Hirota, A., Bisorbibetanone, a novel oxidized sorbicillin dimer, with 1,1 -diphenyl-2-pycrylhydrazyl-radical scavenging activity from a fungus. Tetrahedron Lett., 40, 5203-5206 (1999).
7. Hirota, A., Nemoto, A., Tsuchiya, Y., Hojo, H., and Abe, N., Isolation of a 2-pyrone compound as an antioxidant from a fungus and its new reaction product with l, l-diphenyl-2-picrylhydrazyl radical. Biosci. Biotechnol. Biochem., 63, 418-420 (1999).
8. Masuda, T., Hidaka, K., Shinohara, A., Maekawa, T., Takeda, Y., and Yamaguchi, H. Chemical studies on antioxidant mechanism of curcuminoid: analysis of radical reaction products from curcumin. J. Agric. Food Chem., 47, 71-77 (1999).
9. Yoshida, T., Mori, K., Hatano, T., Okumura, T., Uehara, I., Komagoe, K., Fujita, Y., and Okuda, T., Studies on inhibition mechanism of antioxidation by tannins and flavonoids. V. Radical-scavenging effects of tannins and related polyphenols on 1,1-diphenyl-2-picrylhydrazyl radical. Chem. Pharm. Bull., 37, 1919-1921 (1989).
10. Sawai, Y. and Sakata, K., NMR analytical approach to clarify the antioxidative molecular mechanism of catechins using l, l-diphenyl-2-picrylhydrazyl radical. J. Agric. Food Chem., 46, 111-114 (1998).
11. Yoshiki, Y. and Okubo, K., Active oxygen scavenging activity of DDMP (2,3-dihydro-2,5-dihydroxy-6-methyl-4F/-pyran-4-one) saponin in soybean seed. Biosci. Biotechnol. Biochem., 59, 1556-1557 (1995).