A new convenient approach to preparation of 5 or 6 or 7-nitro-1,2,3,4- tetrahydrisoquinolines and 2-alkylsulfonyl-5 or 6 or 7-nitro-1,2,3,4- tetrahydroisoquinolines

Synthetic Communications

Volumn 30, Issue 9, 2000, Pages 1581-1585

  Ran, Chongzhao ^a   Wang, Guoping ^a   Wu, Taizhi ^a   Xie, Meihua ^a  

^a Shanghai Inst Pharmaceutical I   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROBROMIC ACID; ISOQUINOLINE DERIVATIVE; SULFONE;

ARTICLE; CYCLIZATION; SYNTHESIS;

EID: 0034128202     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397910008087192     Document Type: Article

References (8)

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3. A.McCoubrey, D.W. Mathieson, J.Chem.Soc. 1950,1833;
4. J.F.Ajao, C.W.Bird, J.Heterocycl.Chem. 1985, 22:329;
5. M.Tercel, W.R.Wilson, J.Med.Chem. 1996, 39:1084;
6. G.E.Stokker, Tetrahedron Letters 1996, 37(31):5453;
7. G.J.Quallich, T.W.Makowski, J.Org. Chem. 1998 , 63:4116;
8. 3 δ ppm), 7.88(d, 1H), 7.82(s, 1H), 7.17(d, 1H),4.44(s, 2H), 3.52(1, 2H),3.02(t,2H), 2.84(s,3H). (2c) was hydrolyzed with 40%HBr solution to give(3c). yield: 92%.