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Volumn 24, Issue 5, 2000, Pages 552-558

Effects of hyperglycaemia and hyperinsulinaemia on plasma amino acid levels in obese subjects with normal glucose tolerance

Author keywords

Amino acids; Glucose; Hyperglycaemic clamp; Insulin; Insulin resistance; Obesity; Somatostatin

Indexed keywords

AMINO ACID; FATTY ACID; GLUCAGON; GLUCOSE; INSULIN; SOMATOSTATIN; STILAM;

EID: 0034127169     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0801195     Document Type: Article
Times cited : (12)

References (41)
  • 2
    • 0020319478 scopus 로고
    • Insulin secretion, insulin resistance, and obesity
    • 2 DeFronzo RA. Insulin secretion, insulin resistance, and obesity. Int J Obes 1982; 6: 73-82.
    • (1982) Int J Obes , vol.6 , pp. 73-82
    • DeFronzo, R.A.1
  • 3
    • 0030967580 scopus 로고    scopus 로고
    • Glucose and free fatty acid metabolism in human obesity. Relationship to insulin resistance
    • 3 Bonadonna RC, Bonora E. Glucose and free fatty acid metabolism in human obesity. Relationship to insulin resistance. Diabetes Rev 1997; 5: 21-51.
    • (1997) Diabetes Rev , vol.5 , pp. 21-51
    • Bonadonna, R.C.1    Bonora, E.2
  • 4
    • 0018602014 scopus 로고
    • Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
    • 4 National Diabetes Data Group. Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 1979; 28: 1039-1057.
    • (1979) Diabetes , vol.28 , pp. 1039-1057
  • 5
    • 0018896297 scopus 로고
    • Mechanism of insulin resistance in human obesity. Evidence for receptor and post-receptor defects
    • 5 Kolterman OG, Insel J, Saekow M, Olefsky JM. Mechanism of insulin resistance in human obesity. Evidence for receptor and post-receptor defects. J Clin Invest 1980; 83: 1272-1284.
    • (1980) J Clin Invest , vol.83 , pp. 1272-1284
    • Kolterman, O.G.1    Insel, J.2    Saekow, M.3    Olefsky, J.M.4
  • 8
    • 0025303071 scopus 로고
    • Plasma free fatty acid concentration during hyperglycemic glucose clamp with and without somatostatin infusion in obese subjects with normal glucose tolerance
    • 8 Zancanaro C, Cigolini M, Bonora E, Moghetti P, Cacciatori V, Querena M, Muggeo M. Plasma free fatty acid concentration during hyperglycemic glucose clamp with and without somatostatin infusion in obese subjects with normal glucose tolerance. Int J Obesity 1990; 14: 551-557.
    • (1990) Int J Obesity , vol.14 , pp. 551-557
    • Zancanaro, C.1    Cigolini, M.2    Bonora, E.3    Moghetti, P.4    Cacciatori, V.5    Querena, M.6    Muggeo, M.7
  • 9
    • 0025963777 scopus 로고
    • The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and noninsulin-dependent diabetes mellitus
    • 9 Groop LC, Saloranta C, Shank M, Bonadonna RC, Ferranini E, De Fronzo RA. The role of free fatty acid metabolism in the pathogenesis of insulin resistance in obesity and noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1991; 72: 96-107.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 96-107
    • Groop, L.C.1    Saloranta, C.2    Shank, M.3    Bonadonna, R.C.4    Ferranini, E.5    De Fronzo, R.A.6
  • 11
    • 0017992236 scopus 로고
    • Blood amino acid levels in patients with insulin excess (functioning insulinoma) and insulin deficiency (diabetic ketosis)
    • 11 Berger M, Zimmerman-Telschov H, Bercthold P, Drost H, Müller WA, Griest A, Zimmerman H. Blood amino acid levels in patients with insulin excess (functioning insulinoma) and insulin deficiency (diabetic ketosis). Metabolism 1978; 27: 793-799.
    • (1978) Metabolism , vol.27 , pp. 793-799
    • Berger, M.1    Zimmerman-Telschov, H.2    Bercthold, P.3    Drost, H.4    Müller, W.A.5    Griest, A.6    Zimmerman, H.7
  • 12
    • 0014669160 scopus 로고
    • Plasma amino acid levels and insulin secretion in obesity
    • 12 Felig P, Marliss E, Cahill GF. Plasma amino acid levels and insulin secretion in obesity. N Engl J Med 1969; 281: 811-816.
    • (1969) N Engl J Med , vol.281 , pp. 811-816
    • Felig, P.1    Marliss, E.2    Cahill, G.F.3
  • 13
    • 0014884444 scopus 로고
    • Hormone and amino acid levels in altered nutritional states
    • 13 Adibi SA, Drash AL. Hormone and amino acid levels in altered nutritional states. J Lab Clin Med 1970; 76: 722-732.
    • (1970) J Lab Clin Med , vol.76 , pp. 722-732
    • Adibi, S.A.1    Drash, A.L.2
  • 15
    • 0022366113 scopus 로고
    • Evidence for diminished 5-hydroxytryptamine biosynthesis in obese diabetic and nondiabetic humans
    • 15 Ashley DVM, Fleury MO, Golay A, Maeder E, Leathwood PD. Evidence for diminished 5-hydroxytryptamine biosynthesis in obese diabetic and nondiabetic humans. Am J Clin Nutr 1985; 42: 1240-1245.
    • (1985) Am J Clin Nutr , vol.42 , pp. 1240-1245
    • Ashley, D.V.M.1    Fleury, M.O.2    Golay, A.3    Maeder, E.4    Leathwood, P.D.5
  • 16
    • 0023904645 scopus 로고
    • Plasma amino acids and insulin levels in obesity response to carbohydrate intake and tryptophan supplements
    • 16 Caballero B, Finer N, Wurtman RJ. Plasma amino acids and insulin levels in obesity response to carbohydrate intake and tryptophan supplements. Metabolism 1988; 37: 672-676.
    • (1988) Metabolism , vol.37 , pp. 672-676
    • Caballero, B.1    Finer, N.2    Wurtman, R.J.3
  • 17
    • 0026056770 scopus 로고
    • Protein metabolism in obesity: Effects of body fat distribution and hyperinsulinemia on leucine turnover
    • 17 Jensen MD, Haymond MW. Protein metabolism in obesity: effects of body fat distribution and hyperinsulinemia on leucine turnover. Am J Clin Nutr 1991; 53: 172-176.
    • (1991) Am J Clin Nutr , vol.53 , pp. 172-176
    • Jensen, M.D.1    Haymond, M.W.2
  • 19
    • 0028256521 scopus 로고
    • Differential effects of insulin on whole-body proteolysis and glucose metabolism in normal-weight, obese and reduced-obese women
    • 19 Welle S, Statt M, Barnard R, Amatruda J. Differential effects of insulin on whole-body proteolysis and glucose metabolism in normal-weight, obese and reduced-obese women. Metabolism 1994; 43: 441-445.
    • (1994) Metabolism , vol.43 , pp. 441-445
    • Welle, S.1    Statt, M.2    Barnard, R.3    Amatruda, J.4
  • 20
    • 0021039123 scopus 로고
    • Effect of poor diabetic control and obesity on whole-body protein metabolism in man
    • 20 Nair KS, Garrow JS, Ford C, Mahler RF, Halliday D. Effect of poor diabetic control and obesity on whole-body protein metabolism in man. Diabetologia 1983; 25: 400-403.
    • (1983) Diabetologia , vol.25 , pp. 400-403
    • Nair, K.S.1    Garrow, J.S.2    Ford, C.3    Mahler, R.F.4    Halliday, D.5
  • 21
    • 0023615848 scopus 로고
    • Failure of carbohydrate to spare leucine oxidation in obese subjects
    • 21 Nair KS, Halliday D, Ford GC, Heels S, Garrow JS. Failure of carbohydrate to spare leucine oxidation in obese subjects. Int J Obes 1987; 11: 537-544.
    • (1987) Int J Obes , vol.11 , pp. 537-544
    • Nair, K.S.1    Halliday, D.2    Ford, G.C.3    Heels, S.4    Garrow, J.S.5
  • 23
    • 0026003658 scopus 로고
    • Differential effects of insulin resistance on leucine and glucose kinetics in obesity
    • 23 Caballero B, Wurtman RJ. Differential effects of insulin resistance on leucine and glucose kinetics in obesity. Metabolism 1991; 40: 51-58.
    • (1991) Metabolism , vol.40 , pp. 51-58
    • Caballero, B.1    Wurtman, R.J.2
  • 24
    • 0029924108 scopus 로고    scopus 로고
    • Insulin and hyperaminoacidemia regulate by a different mechanism leucine turnover and oxidation in obesity
    • 24 Luzi L, Castellino P, DeFronzo RA. Insulin and hyperaminoacidemia regulate by a different mechanism leucine turnover and oxidation in obesity. Am J Physiol 1996; 270: E273-E281.
    • (1996) Am J Physiol , vol.270
    • Luzi, L.1    Castellino, P.2    DeFronzo, R.A.3
  • 25
    • 0027130670 scopus 로고
    • Acute hyperglycemia enhances proteolysis in normal man
    • 25 Flakoll PJ, Hill JO, Abumrad NN. Acute hyperglycemia enhances proteolysis in normal man. Am J Physiol 1993; 265: E715-E721.
    • (1993) Am J Physiol , vol.265
    • Flakoll, P.J.1    Hill, J.O.2    Abumrad, N.N.3
  • 26
    • 0018520840 scopus 로고
    • Glucose clamp technique: A method for quantifying insulin secretion and resistance
    • 26 DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 28: E214-E223.
    • (1979) Am J Physiol , vol.28
    • DeFronzo, R.A.1    Tobin, J.D.2    Andres, R.3
  • 27
    • 0023097429 scopus 로고
    • Plasma clearances of branched-chain amino acids in control subjects and in patients with cirrhosis
    • 27 Marchesini G, Bianchi GP, Vilstrup H, Checchia GA, Patrono D, Zoli M. Plasma clearances of branched-chain amino acids in control subjects and in patients with cirrhosis. J Hepatol 1987; 4: 108-117.
    • (1987) J Hepatol , vol.4 , pp. 108-117
    • Marchesini, G.1    Bianchi, G.P.2    Vilstrup, H.3    Checchia, G.A.4    Patrono, D.5    Zoli, M.6
  • 28
    • 0001196262 scopus 로고
    • Multiple range test for correlated and heteroscedastic means
    • 28 Duncan DB. Multiple range test for correlated and heteroscedastic means. Biometrics 1957; 13: 164-204.
    • (1957) Biometrics , vol.13 , pp. 164-204
    • Duncan, D.B.1
  • 30
    • 0030851478 scopus 로고    scopus 로고
    • Protein metabolism in human obesity: Relationship with glucose and lipid metaboism and with visceral adipose tissue
    • 30 Solini A, Bonora E, Bonadonna R, Castellino P, DeFronzo RA. Protein metabolism in human obesity: relationship with glucose and lipid metaboism and with visceral adipose tissue. J Clin Endocrinol Metab 1997; 82: 2252-2258.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 2252-2258
    • Solini, A.1    Bonora, E.2    Bonadonna, R.3    Castellino, P.4    DeFronzo, R.A.5
  • 31
    • 0028315970 scopus 로고
    • Insulin-induced decline of plasma amino acid concentrations in obese subjects with and without non-insulin dependent diabetes
    • 31 Pijl H, Potter van Loon J, Toornvliet AC, Radder JK, Onkenhout W, Frolich M, Meinders AE. Insulin-induced decline of plasma amino acid concentrations in obese subjects with and without non-insulin dependent diabetes. Metabolism 1994; 43: 640-646.
    • (1994) Metabolism , vol.43 , pp. 640-646
    • Pijl, H.1    Potter Van Loon, J.2    Toornvliet, A.C.3    Radder, J.K.4    Onkenhout, W.5    Frolich, M.6    Meinders, A.E.7
  • 32
    • 0029037801 scopus 로고
    • Failure of complete suppression of endogenous glucose production by euglycemic hyperinsulinemia in normal humans
    • 32 Neely RD, Harper R, Rooney DP, Ennis CN, Bell PM, Trimble ER. Failure of complete suppression of endogenous glucose production by euglycemic hyperinsulinemia in normal humans. Eur J Clin Invest 1995; 25: 447-453.
    • (1995) Eur J Clin Invest , vol.25 , pp. 447-453
    • Neely, R.D.1    Harper, R.2    Rooney, D.P.3    Ennis, C.N.4    Bell, P.M.5    Trimble, E.R.6
  • 33
    • 0027500242 scopus 로고
    • Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus
    • 33 Del Prato S, Bonadonna RC, Bonora E, Gulli G, Solini A, Shank M, De Fronzo RA. Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitus. J Clin Invest 1993; 91: 484-494.
    • (1993) J Clin Invest , vol.91 , pp. 484-494
    • Del Prato, S.1    Bonadonna, R.C.2    Bonora, E.3    Gulli, G.4    Solini, A.5    Shank, M.6    De Fronzo, R.A.7
  • 35
    • 0027952744 scopus 로고
    • The opposing effects of insulin and hyperglycemia in modulating amino acid metabolism during a glucose tolerance test in lean and obese subjects
    • 35 Rice DE, Flakoll PJ, May MM, Hill JO, Abumrad NN. The opposing effects of insulin and hyperglycemia in modulating amino acid metabolism during a glucose tolerance test in lean and obese subjects. Metabolism 1994; 43: 211-216.
    • (1994) Metabolism , vol.43 , pp. 211-216
    • Rice, D.E.1    Flakoll, P.J.2    May, M.M.3    Hill, J.O.4    Abumrad, N.N.5
  • 37
    • 0031154906 scopus 로고    scopus 로고
    • Effects of hepatic glycogen content on hepatic insulin action in humans: Alteration in the relative contributions of glycogenolysis and gluconeogenesis to endogenous glucose production
    • 37 Wise S, Nielsen M, Rizza R. Effects of hepatic glycogen content on hepatic insulin action in humans: alteration in the relative contributions of glycogenolysis and gluconeogenesis to endogenous glucose production. J Clin Endocrinol Metab 1997; 82: 1828-1833.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1828-1833
    • Wise, S.1    Nielsen, M.2    Rizza, R.3
  • 38
    • 0021740136 scopus 로고
    • Effects of glucose on alanine-derived urea synthesis
    • 38 Vilstrup H. Effects of glucose on alanine-derived urea synthesis. Clin Physiol 1984; 4: 495-507.
    • (1984) Clin Physiol , vol.4 , pp. 495-507
    • Vilstrup, H.1
  • 39
    • 0021363892 scopus 로고
    • Effects of glucagon on plasma amino acids
    • 39 Boden G, Rezvanj I, Owen OE. Effects of glucagon on plasma amino acids. J Clin Invest 1984; 73: 785-793.
    • (1984) J Clin Invest , vol.73 , pp. 785-793
    • Boden, G.1    Rezvanj, I.2    Owen, O.E.3
  • 40
    • 0028038975 scopus 로고
    • Effects of glucose on hepatic conversion of aminonitrogen to urea in patients with cirrhosis: Relationship to glucagon
    • 40 Hamberg O, Vilstrup H. Effects of glucose on hepatic conversion of aminonitrogen to urea in patients with cirrhosis: relationship to glucagon. Hepatology 1994; 19: 45-54.
    • (1994) Hepatology , vol.19 , pp. 45-54
    • Hamberg, O.1    Vilstrup, H.2
  • 41
    • 0023627062 scopus 로고
    • Hyperglucagonemia during insulin deficiency accelerates protein catabolism
    • 41 Nair KS, Halliday D, Matthews DE, Welle SL. Hyperglucagonemia during insulin deficiency accelerates protein catabolism. Am J Physiol 1987; 253: E208-E213.
    • (1987) Am J Physiol , vol.253
    • Nair, K.S.1    Halliday, D.2    Matthews, D.E.3    Welle, S.L.4


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