Comparative molecular modeling on 3D-structure of opioid receptor-like 1 receptor

Acta Pharmacologica Sinica

Volumn 21, Issue 6, 2000, Pages 529-535

  Huang, Xiao Qin ^a   Jiang, Hua Liang ^a   Luo, Xiao Min ^a   Chen, Kai Xian ^a   Zhu, You Cheng ^a   Ji, Ru Yun ^a   Cao, Yang ^b  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b SOOCHOW UNIVERSITY   (China)

Author keywords

Frog rhodopsin; Molecular mechanics; Molecular models; ORL1 receptors; Templates

Indexed keywords

OPIATE RECEPTOR; RHODOPSIN;

ARTICLE; BINDING AFFINITY; COMPUTER AIDED DESIGN; GEOMETRY; HYDROGEN BOND; LIGAND BINDING; MOLECULAR MODEL; PROTEIN STRUCTURE; QUANTUM MECHANICS; SEQUENCE HOMOLOGY; VALIDATION PROCESS;

AMINO ACID SEQUENCE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; RECEPTORS, OPIOID; RHODOPSIN; SEQUENCE ALIGNMENT; TEMPLATES, GENETIC;

EID: 0034126544     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Mollereau C, Parmentier M, Mailleux P, Meunier JC. ORL1, a novel member of the opioid receptor family, cloning, functional expression and localization. FEBS Lett 1991; 341; 33-8.
2. Butour JL, Moisand C, Mazarguil H, Mollereau C, Meunier JC. Recognition and activation of the opioid receptor-like ORL1 receptor by nociceptin, nociceptin analogs and opioids. Eur J Pharmacol 1997; 321: 97-103.
3. Sanchez R, Sali A. Advances in comparative protein-structure modeling. Curr Opin Struct Biol 1997; 7: 206-14.
4. Kyte J, Doolittle RF. A simple method for displaying the hydropathic character of a protein. J Mol Biol 1982; 157: 105-32.
5. Pogozheva ID, Lomize AL, Mosberg HI. The transmembrane 7-α-bundle of rhodopsin; distance geometry calculations with hydrogen bonding constraints. Biophys J 1997; 70: 1963-85.