Development of a new inhibitor of glucosylceramide synthase

Journal of Biochemistry

Volumn 127, Issue 3, 2000, Pages 485-491

  Jimbo, Masayuki ^a   Yamagishi, Kiwamu ^a   Yamaki, Toshiaki ^b   Nunomura, Katsuyuki ^b   Kabayama, Kazuya ^c   Igarashi, Yasuyuki ^c   Inokuchi, Jin Ichi ^c  

^a SEIKAGAKU CORPORATION   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Ceramide; Glucosylceramide synthase; Glycosphingolipids; Inhibitor; PBPP; PDMP

Indexed keywords

1 PHENYL 2 BENZYLOXYCARBONYLAMINO 3 PYRROLIDINO 1 PROPANOL; 2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; CERAMIDE GLUCOSYLTRANSFERASE; CERAMIDE GLUCOSYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL GROWTH; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; GROWTH INHIBITION; HUMAN; HUMAN CELL; HYDROPHOBICITY; INHIBITION KINETICS; NONHUMAN; REACTION ANALYSIS; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALIA;

EID: 0034126244     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022631     Document Type: Article

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