Regulation of human eotaxin generation by Th1-/Th2-derived cytokines

International Archives of Allergy and Immunology

Volumn 122, Issue SUPPL. 1, 2000, Pages 54-58

  Miyamasu, Misato ^a   Misaki, Yoshikata ^a   Yamaguchi, Masao ^a   Yamamoto, Kazuhiko ^a   Morita, Yutaka ^a   Matsushima, Kouji ^a   Nakajima, Toshiharu ^a   Hirai, Koichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Allergy; Eosinophil; Eotaxin; Fibroblast; IFN ; IL 4; Th1 Th2 paradigm; TNF

Indexed keywords

CYTOKINE; EOTAXIN; GAMMA INTERFERON; INTERLEUKIN 4; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; TH1 CELL; TH2 CELL; VASCULAR ENDOTHELIUM;

EID: 0034126084     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000053634     Document Type: Article

References (19)

1. Ponath PD, Qin S, Post TW, Wang J, Wu L, Gerard NP, Newman W, Gerard C, Mackay CR: Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med 1996;183:2437-2448.
2. Heath H, Qin S, Rao P, Wu L, LaRosa G, Kassam N, Ponath PD, Mackay CR: Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. J Clin Invest 1997;99:178-184.
3. Yamada H, Hirai K, Miyamasu M, Iikura M, Misaki Y, Shoji S, Takaishi T, Kasahara T, Morita Y, Ito K: Eotaxin is a potent chemotaxin for human basophils. Bioehem Biophys Res Commun 1997;231:365-368.
4. Uguccioni M, Mackay CR, Ochensberger B, Loetscher P, Rhis S, LaRosa GJ, Rao P, Ponath PD, Baggiolini M, Dahinden CA: High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines. J Clin Invest 1997;100:1137-1143.
5. Rothenberg ME, Luster AD, Leder P: Murine eotaxin: An eosinophil chemoattractant inducible in endothelial cells and in interleukin-4-induced tumor suppression. Proc Natl Acad Sci USA 1995;92:8960-8964.
6. Mochizuki M, Bartels J, Mallet AI, Christophers E, Schroder JM: IL-4 induces eotaxin: A possible mechanism of selective eosinophil recruitment in helminth infection and atopy. J Immunol 1998;160:60-68.
7. Collins PD, Marleau S, Griffiths-Johnson DA, Jose PJ, Williams TJ: Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. J Exp Med 1995;182:1169-1174.
8. Palframan RT, Collins PD, Williams TJ, Rankin SM: Eotaxin induces a rapid release of eosinophils and their progenitors from the bone marrow. Blood 1998;91:2240-2248.
9. Lamkhioued B, Renzi PM, Abi-Younes S, Garcia-Zepeda EA, Allakhverdi Z, Ghaffar O, Rothenberg ME, Luster AD, Hamid Q: Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation. J Immunol 1997;159:4593-4601.
10. Garcia-Zepeda EA, Rothenberg ME, Ownbey RT, Celestin J, Leder P, Luster AD: Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat Med 1996;2: 449-456.
11. Lilly CM, Nakamura H, Kesselman H, Nagler-Anderson C, Asano K, Garcia-Zepeda EA, Rothenberg ME, Drazen JM, Luster AD: Expression of eotaxin by human lung epithelial cells: Induction by cytokines and inhibition by glucocorticoids. J Clin Invest 1997;99:1767-1773.
12. Miyamasu M, NakajimaT, Misaki Y, Izumi S, Tsuno N, Ohta K, Kasahara T, Yamamoto K, Morita Y, Hirai K: Dermal fibroblasts represent a potent major source of human eotaxin: In vitro production and cytokine-mediated regulation. Cytokine 1999;Oct;11:751-758.
13. Nakajima T, Yamada H, Iikura M, Miyamasu M, Izumi S, Shida H, Ohta K, Imai T, Yoshie O, Mochizuki M, Schroder JM, Morita Y, Yamamoto K, Hirai K: Intracellular localization and release of eotaxin from normal eosinophils. FEBS Lett 1998;434:226-230.
14. Miyamasu M, Hirai K, Takahashi Y, Iida M, Yamaguchi M, Koshino T, Takaishi T, Morita Y, Ohta K, Kasahara T, Ito K: Chemotactic agonists induce cytokine generation in eosinophils. J Immunol 1995;154:1339-1349.
15. Izumi S, Hirai K, Miyamasu M, Takahashi Y, Misaki Y, Takaishi T, Morita Y, Matsushima K, Ida N, Nakamura H, Kasahara T, Ito K: Expression and regulation of monocyte chemoattractant protein-1 by human eosinophils. Eur J Immunol 1997;27:816-824.
16. Miyamasu M, Yamaguchi M, Nakajima T, Misaki Y, Morila Y, Matsushima K, Yamamoto K, Hirai K: Th1-derived cytokine IFN-gamma is a potent inhibitor of eotaxin synthesis in vitro. Int Immunol 1999;11:1001-1004.
17. Bartels J, Schluter C, Richter E, Noso N, Kulke R, Christophers E, Schroder JM: Human dermal fibroblasts express eotaxin: Molecular cloning, mRNA expression, and identification of eotaxin sequence variants. Biochem Biophys Res Commun 1996;225:1045-1051.
18. Iwamoto I, Nakajima H, Endo H, Yoshida S: Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+ T cells. J Exp Med 1993;177:573-576.
19. Kung TT, Stelts D, Zurcher JA, Watnick AS, Jones H, Mauser PJ, Fernandez X, Umland S, Kreutner W, Chapman RW, Egan RW: Mechanisms of allergic pulmonary eosinophilia in the mouse. J Allergy Clin Immunol 1994;94:1217-1224.