An efficient method for the preparation of enantiomerically pure N- acylarylsulfonamides having an asymmetric center at the α-position: Condensation of acid chlorides and arylsulfonamides under solid-liquid two- phase conditions

Synthesis

Volumn , Issue 6, 2000, Pages 784-788

  Ishizuka, Natsuki ^a   Matsumura, Ken ichi ^a   Hayashi, Kunio ^a   Sakai, Katsunori ^a   Yamamori, Teruo ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

Chiral N acylarylsulfonamides; Chiral phenylacetic acid; Powdered alkaline hydroxide; Racemization; Solid liquid two phase conditions

Indexed keywords

CARBONYL DERIVATIVE; CHLORIDE; PHENYLACETIC ACID; SULFONAMIDE;

ACYLATION; ARTICLE; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CRYSTALLIZATION; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; POLYMERIZATION; SYNTHESIS;

EID: 0034125979     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-6270     Document Type: Article

References (27)

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