Pyridazinones with a pendant acylsulfonamide moiety as endothelin receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 3, 1997, Pages 275-280

  Dorsch, Dieter ^a   Mederski, Werner W K R ^a   Osswald, Mathias ^a   Devant, Ralf M ^a   Schmitges, Claus Jochen ^a   Christadler, Maria ^a   Wilm, Claudia ^a  

^a MERCK KGAA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; L 749329; N (4 ISOPROPYLPHENYLSULFONYL) 2 (1,3 BENZODIOXOL 5 YL) 2 (3 METHYL 6 OXOPYRIDAZINO)ACETAMIDE; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AORTA; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENANTIOMER; ENDOTHELIUM; KIDNEY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; SWINE;

EID: 0031552089     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00617-8     Document Type: Article

References (22)

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