Secreted and membrane-associated matrix metalloproteinases of IL-2- activated NK cells and their inhibitors

Journal of Immunology

Volumn 164, Issue 11, 2000, Pages 5883-5889

  Kim, Myoung H ^a   Kitson, Richard P ^a   Albertsson, Per ^b   Nannmark, Ulf ^b   Basse, Per H ^c   Kuppen, Peter J K ^d   Hokland, Marianne E ^e   Goldfarb, Ronald H ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B; INTERLEUKIN 2; MATRIX METALLOPROTEINASE; STROMELYSIN 3; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ADOPTIVE TRANSFER; ANIMAL CELL; ARTICLE; BASEMENT MEMBRANE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; EXTRAVASATION; METASTASIS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

EID: 0034123509     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.11.5883     Document Type: Article

References (67)

1. Matrisian, L. M. 1992. The matrix-degrading metalloproteinases. BioEssays 14: 455.
2. Westermarck, J., and V. M. Kahari. 1999. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J. 13:781.
3. Nagase, H., and J. F. Woessner Jr. 1999. Matrix metalloproteinases. J. Biol. Chem. 274:21491.
4. Shapiro, S. D., and R. M. Senior. 1999. Matrix metalloproteinases: matrix degradation and more. Am. J. Respir. Cell Mol. Biol. 20:1100.
5. Goetzl, E. J., M. J. Banda, and D. Leppert. 1996. Matrix metalloproteinases in immunity. J. Immunol. 156:1.
6. Crawford, H. C., and L. M. Matrisian. 1996. Mechanisms controlling the transcription of matrix metalloproteinase genes in normal and neoplastic cells. Enzyme Protein 49:20.
7. Parsons, S. L., S. A. Watson, P. D. Brown, H. M. Collins, and R. J. Steele. 1997. Matrix metalloproteinases. Br. J. Surg. 84:160.
8. Fini, M. E., J. R. Cook, R. Mohan, and C. E. Brinckerhoft. 1998. Matrix Metalloproteinases. W. C. Parks and R. P. Mecham, eds. Academic Press, San Diego, p. 299.
9. Gomez, D. E., D. F. Alonso, H. Yoshiji, and U. P. Thorgeirsson. 1997. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur J. Cell Biol. 74:111.
10. Edwards, D. R., P. Waterhouse, M. L. Holman, and D. T. Denhardt. 1986. A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-polentiating activity: evidence for inducible and constitutive transcripts. Nucleic Acids Res. 14:8863.
11. Fujimoto, N., H. Tokai, K. Iwata, Y. Okada, and T. Hayakawa. 1995. Determination of tissue inhibitor of metalloproteinases-2 (TIMP-2) in experimental animals using monoclonal antibodies against TIMP-2-specific oligopeptides. J. Immunol. Methods 187:33.
12. Liu, Y. E., M. Wang, J. Greene, J. Su, S. Ullrich, H. Li, S. Sheng, P. Alexander, Q. A. Sang, and Y. E. Shi. 1997. Preparation and characterization of recombinant tissue inhibitor of metalloproteinase 4 (TIMP-4). J. Biol. Chem. 272:20479.
13. Leco, K. J., R. Khokha, N. Pavloff, S. P. Hawkes, and D. R. Edwards. 1994. Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues. J. Biol. Chem. 269:9352.
14. Leppert, D., E. Waubant, R. Galardy, N. W. Bunnett, and S. L. Hauser. 1995. T cell gelalinases mediate basement membrane transmigration in vitro. J. Immunol. 154:4379.
15. Romanic, A. M., and J. A. Madri. 1994. The induction of 72-kD gelalinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent. J. Cell Biol. 125:1165.
16. Xia, M., D. Leppert, S. L. Hauser, S. P. Sreedharan, P. J. Nelson, A. M. Krensky, and E. J. Goetzl. 1996. Stimulus specificity of matrix metalloproteinase dependence of human T cell migration through a model basement membrane. J. Immunol. 156:160.
17. Mollinedo, F., C. Gajate, and D. L. Schneider. 1991. Cytochrome b co-fractionates with gelatinase-containing granules in human neutrophils. Mol. Cell. Biochem. 105:49.
18. Mollinedo, F., R. Pulido, P. M. Lacal, and F. Sanchez-Madrid. 1991. Mobilization of gelatinase-rich granules as a regulatory mechanism of early functional responses in human neutrophils. Scand. J. Immunol. 34:33.
19. Hasty, K. A., T. F. Pourmotabbed, G. I. Goldberg, J. P. Thompson, D. G. Spinella, R. M. Stevens, and C. L. Mainardi, 1990. Human neutrophil collagenase: a distinct gene product with homology to other matrix metalloproteinases. J. Biol. Chem. 265:11421.
20. Shapiro, S. D., D. K. Kobayashi, and T. J. Ley. 1993. Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. J. Biol. Chem. 268:23824.
21. Shapiro, S. D., D. K. Kobayashi, A. P. Pentland, and H. G. Welgus. 1993. Induction of macrophage metalloproteinases by extracellular matrix: evidence for enzyme-and substrate-specific responses involving prostaglandin-dependent mechanisms. J. Biol. Chem. 268:8170.
22. Busiek, D. F., V. Baragi, L. C. Nehring, W. C. Parks, and H. G. Welgus. 1995. Matrilysin expression by human mononuclear phagocytes and its regulation by cytokines and hormones. J. Immunol. 154:6484.
23. Birkedal-Hansen, H., W. G. Moore, M. K. Bodden, L. J. Windsor, B. Birkedal-Hansen, A. DeCarlo, and J. A. Engler. 1993. Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med. 4:197.
24. Welgus, H. G., E. J. Campbell, J. D. Cury, A. Z. Eisen, R. M. Senior, S. M. Wilhelm, and G. I. Goldberg. 1990. Neutral metalloproteinases produced by human mononuclear phagocytes: enzyme profile, regulation, and expression during cellular development. J. Clin. Invest. 86:1496.
25. Kayagaki, N., A. Kawasaki, T. Ebata, H. Ohmoto, S. Ikeda, S. Inoue, K. Yoshino, K. Okumura, and H. Yagita. 1995. Metalloproteinase-mediated release of human Fas ligand. J. Exp. Med. 182:1777.
26. Gearing, A. J., P. Beckett, M. Christodoulou, M. Churchill, J. Clements, A. H. Davidson, A. H. Drummond, W. A. Galloway, R. Gilbert, J. L. Gordon, et al. 1994. Processing of tumor necrosis factor-α precursor by metalloproteinases. Nature 370:555.
27. Cornelius, L. A., L. C. Nehring, E. Harding, M. Bolanowski, H. G. Welgus, D. K. Kobayashi, R. A. Pierce, and S. D. Shapiro. 1998. Matrix metalloproteinases generate angiostatin: effects on neovascularization. J. Immunol. 161:6845.
28. Patterson, B. C., and Q. A. Sang. 1997. Angiostatin-converting enzyme activities of human matrilysin (MMP-7) and gelatinase B/type IV collagenase (MMP-9). J. Biol. Chem. 272:28823.
29. Rosenberg, S. A., M. T. Lotze, L. M. Muul, A. E. Chang, F. P. Avis, S. Leitman, W. M. Linehan, C. N. Robertson, R. E. Lee, J. T. Rubin, et al. 1987. A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. N. Engl. J. Med. 316:888.
30. Goldfarb, R. H., T. L. Whiteside, P. H. Basse, W. C. Lin, N. Vujanovic, and R, B. Herberman. 1994. Natural killer cells and gene therapy: potential of gene transfection for optimizing effector cell functions and for targeting gene products into tumor metastases. Nat. Immun. 13:131.
31. Goldfarb, R. H., and K. W. Brunson. 1995. Antimetastatic therapy. In Biological Therapy of Cancer, 2nd Ed. V. T. J. DeVita, S. Hellman, and S. A. Rosenberg, eds. J.B. Lippincott and Company, Philadelphia, p. 853.
32. Tanguay, S., C. D. Bucana, M. R. Wilson, I. J. Fidler, A. C. von Eschenbach, and J. J. Killion. 1994. In vivo modulation of macrophage tumoricidal activity by oral administration of the liposome-encapsulated macrophage activator CGP 19835A. Cancer Res. 54:5882.
33. Killion, J. J., and I. J. Fidler. 1994. Systemic targeting of liposome-encapsulated immunomodulators to macrophages for treatment of cancer metastasis. Immuno-Methods 4:273.
34. Svane, I. M., M. Boesen, and A. M. Engel. 1999. The role of cytotoxic T-lymphocytes in the prevention and immune surveillance of tumors: lessons from normal and immunodeficient mice. Med. Oncol. 16:223.
35. Basse, P., R. B. Herberman, U. Nannmark, B. R. Johansson, M. Hokland, K. Wasserman, and R. H. Goldfarh. 1991. Accumulation of adoptively transferred adherent, lymphokine-activated killer cells in murine metastases. J. Exp. Med 174:479.
36. Basse, P. H., U. Nannmark, B. R. Johansson, R. B. Herberman, and R. H. Goldfarb. 1991. Establishment of cell-to-cell contact by adoptively transferred adherent lymphokine-activated killer cells with metastatic murine melanoma cells. J. Natl. Cancer Inst. 83:944.
37. Lowin, B., M. C. Peitsch, and J. Tschopp. 1995. Perform and granzymes: crucial effector molecules in cytolytic T lymphocyte and natural killer cell-mediated cytotoxicity. Curr. Top. Microbiol. Immunol. 198:1.
38. Kitson, R. P., P. M. Appasamy, U. Nannmark, P. Albertsson, M. K. Gabauer, and R. H. Goldfarb. 1998. Matrix metalloproteinases produced by rat IL-2 activated natural killer cells. J. Immunol. 160:4248.
39. 2 receptor. Biochemistry 35:7159.
40. Gunji, Y., N. L. Vujanovic, J. C. Hiserodt, R. B. Herberman, and E. Gorelik. 1989. Generation and characterization of purified adherent lymphokine-activated killer cells in mice. J. Immunol. 142:1748.
41. Zhou, H., E. J. Bernhard, F. E. Fox, and P. C. Billings. 1993. Induction of metalloproteinase activity in human T-lymphocytes. Biochim. Biophys. Acta 1177:174.
42. Mackay, A. R., R. H. Corbitt, J. L. Hartzler, and U. P. Thorgeirsson. 1990. Basement membrane type IV collagen degradation: evidence for the involvement of a proteolytic cascade independent of metalloproteinases. Cancer Res. 50:5997.
43. Tanaka, H., K. Hojo, H. Yoshida, T. Yoshioka, and K. Sugita. 1993. Molecular cloning and expression of the mouse 105-kDa gelatinase cDNA. Biochem. Biophys. Res. Commun. 190:732.
44. Fisher, C., B. S. Gilbertson, E. A. Powers, G. Petzold, R. Poorman, and M. A. Mitchell. 1994. Interstitial coliagenase is required for angiogenesis in vitro. Dev. Biol. 162:499.
45. Lohi, J., K. Lehti, J. Westermarck, V. M. Kahari, and J. Keski-Oja. 1996. Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate. Eur. J. Biochem. 239:239.
46. Lehti, K., J. Lohi, H. Valtanen, and J. Keski-Oja. 1998. Proteolytic processing of membrane-type-1 matrix metalloproteinase is associated with gelatinase A activation at the cell surface. Biochem. J. 334:345.
47. Sato, H., T. Takino, Y. Okada, J. Cao, A. Shinagawa, E. Yamamoto, and M. Seiki. 1994. A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature 370:61.
48. Will, H., and B. Hinzmann. 1995. cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment. Eur. J. Biochem. 231:602.
49. Williamson, R. A., F. A. Marston, S. Angal, P. Koklitis, M. Panico, H. R. Morris, A. F. Carne, B. J. Smith, T. J. Harris, and R. B. Freedman. 1990. Bisulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP). Biochem. J. 268:267.
50. Basset, P., J. P. Bellocq, O. Lefebvre, A. Noel, M. P. Chenard, C. Wolf, P. Anglard, and M. C. Rio. 1997. Stromelysin-3: a paradigm for stroma-derived factors implicated in carcinoma progression. Crit. Rev. Oncol. Hematol. 26:43.
51. Murphy, G., J. P. Segain, M. O'Shea, M. Cockett, C. Ioannou, O. Lefebvre, P. Chambon, and P. Basset. 1993. The 28-kDa N-terminal domain of mouse stromelysin-3 has the general properties of a weak metalloproteinase. J. Biol. Chem. 268:15435.
52. Shimizu, S., K. Malik, H. Sejima, J. Kishi, T. Hayakawa, and O. Koiwai. 1992. Cloning and sequencing of the cDNA encoding a mouse tissue inhibitor of metalloproteinase-2. Gene 114:291.
53. Gasson, J. C., D. W. Golde, S. E. Kaufman, C. A. Westbrook, R. M. Hewick, R. J. Kaufman, G. G. Wong, P. A. Temple, A. C. Leary, E. L. Brown, et al. 1985. Molecular characterization and expression of the gene encoding human erythroid-potentiating activity. Nature 315:768.
54. Hayakawa, T., K. Yamashita, E. Ohuchi, and A. Shinagawa. 1994. Cell growth-promoting activity of tissue inhibitor of metalloproteinases-2 (TIMP-2). J. Cell Sci. 107:2373.
55. Stetler-Stevenson, W. G., N. Bersch, and D. W. Golde. 1992. Tissue inhibitor of metalloproteinase-2 (TIMP-2) has erythroid-potentiating activity. FEBS Lett. 296:231.
56. Hayakawa, T., K. Yamashita, K. Tanzawa, E. Uchijima, and K. Iwata. 1992. Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-I) for a wide range of cells: a possible new growth factor in serum. FEBS Lett. 298:29.
57. Murphy, A. N., E. J. Unsworth, and W. G. Stetler-Stevenson. 1993. Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J. Cell. Physiol. 157:351.
58. Chesler, L., D. W. Golde, N. Bersch, and M. D. Johnson. 1995. Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1. Blood 86:4506.
59. Esparza, J., C. Vilardell, J. Calvo, M. Juan, J. Vives, A. Urbano-Marquez, J. Yague, and M. C. Cid. 1999. Fibronectin up-regulates gelatinase B (MMP-9) and induces coordinated expression of gelatinase A (MMP-2) and its activator MT1-MMP (MMP-14) by human T lymphocyte cell lines: a process repressed through RAS/MAP kinase signaling pathways. Blood 94:2754.
60. Ohtani, H., H. Motohashi, H. Sato, M. Seiki, and H. Nagura. 1996. Dual over-expression pattern of membrane-type metalloproteinase-1 in cancer and stromal cells in human gastrointestinal carcinoma revealed by in situ hybridization and immunoelectron microscopy. Int. J. Cancer 68:565.
61. Sato, H., and M. Seiki. 1996. Membrane-type matrix metalloproteinases (MT-MMPs) in tumor metastasis. J. Biochem. 119:209.
62. Sato, H., Y. Okada, and M. Seiki. 1997. Membrane-type matrix metalloproteinases (MT-MMPs) in cell invasion. Thromb Haemostatis 78:497.
63. Belien, A. T., P. A. Paganetti, and M. E. Schwab. 1999. Membrane-type 1 matrix metalloprotease (MTI-MMP) enables invasive migration of glioma cells in central nervous system white matter. J. Cell Biol. 144:373.
64. D'Ortho, M. P., H. Will, S. Atkinson, G. Butler, A. Messent, J. Gavrilovic, B. Smith, R. Timpl, L. Zardi, and G. Murphy. 1997. Membrane-type matrix metalloproteinases 1 and 2 exhibit broad-spectrum proteolytic capacities comparable to many matrix melalloproteinases. Eur. J. Biochem. 250:751.
65. Pei, D., and S. J. Weiss. 1996. Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase-1 process progelatinase A and express intrinsic matrix-degrading activity. J. Biol. Chem. 271:9135.
66. Nannmark, U., B. R. Johansson, J. L. Bryant, M. L. Unger, M. E. Hokland, R. H. Goldfarb, and P. H. Basse. 1995. Microvessel origin and distribution in pulmonary metastases of B16 melanoma: implication for adoptive immunotherapy Cancer Res. 55:4627.
67. Kim, M. H., R. P. Kitson, Y. Xue, and R. H. Goldfarb. 1999. Identification of matrix metalloproteinases (MMPs) produced by rat and mouse IL-2 activated NK (A-NK) cells. FASEB J. 13:1176.