Increased oxidative stress in rats with chronic nitric oxide depletion: Measurement of urinary 8-hydroxy-2'-deoxyguanosine excretion

Redox Report

Volumn 5, Issue 1, 2000, Pages 23-28

  Tsukahara, Hirokazu ^a   Hiraoka, Masahiro ^a   Kobata, Ritsuyo ^a   Hata, Ikue ^a   Ohshima, Yusei ^a   Jiang, Mi Zu ^a   Noiri, Eisei ^b   Mayumi, Mitsufumi ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; AMINOGUANIDINE; ARGININE; BIOLOGICAL MARKER; BUFFER; DRINKING WATER; ISOPROTEIN; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DEPLETION; ENZYME ACTIVITY; HYPERTENSION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; URINALYSIS; URINARY EXCRETION;

ANIMALIA;

EID: 0034119832     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1179/rer.2000.5.1.23     Document Type: Article

References (30)

1. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev 1991; 43: 109-142.
2. Zatz R, Baylis C. Chronic nitric oxide inhibition model six years on. Hypertension 1998; 32: 958-964.
3. Baylis C, Mitruka B, Deng A. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Invest 1992; 90: 278-281.
4. Ribeiro MO, Antunes E, De-Nucci G, Lovisolo SM, Zatz R. Chronic inhibition of nitric oxide synthesis: a new model of arterial hypertension. Hypertension 1992; 20: 298-303.
5. Tagami M, Ikeda K, Nara Y et al. Detailed examination of vascular lesions triggered by an inhibitor of endothelium-derived relaxing factor. Lab Invest 1995; 72: 174-182.
6. Takemoto M, Egashira K, Usui M et al. Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats. J Clin Invest 1997; 99: 278-287.
7. Qiu C, Baylis C. Chronic inhibition of inducible nitric oxide synthase (iNOS) has no effect on blood pressure (BP) or renal hemodynamics in the normal rat [Abstract]. J Am Soc Nephrol 1994; 5: 589.
8. G-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat. Diabetes 1995; 44: 360-364.
9. Tsukahara H, Miura M, Tsuchida S et al. Effect of nitric oxide synthase inhibitors on bone metabolism in growing rats. Am J Physiol 1996; 270: E840-E845.
10. Lunec J. Free radicals: their involvement in disease processes. Ann Clin Biochem 1990; 27: 173-182.
11. Halliwell B. Free radicals, antioxidants, and human disease: curiosity, cause or consequence. Lancet 1994; 344: 721-724.
12. Shigenaga MK, Gimeno CJ, Ames BN, Urinary 8-hydroxy-2′-deoxyguanosine as a biological marker of in vivo oxidative DNA damage. Proc Natl Acad Sci USA 1989; 86: 9697-9701.
13. Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993; 362: 709-715.
14. Loft S, Vistisen K, Ewertz M, Tjønneland A, Overvad K. Poulsen HE. Oxidative DNA damage estimated by 8-hydroxydeoxy-guanosine excretion in humans: influence of smoking, gender and body mass index. Carcinogenesis. 1992; 13: 2241-2247.
15. Adachi S, Kawamura K, Takemoto K. Oxidative damage of nuclear DNA in liver of rats exposed to psychological stress. Cancer Res 1993; 53: 4153-4155.
16. Erhola M, Toyokuni S, Okada K et al. Biomarker evidence of DNA oxidation in lung cancer patients: association of urinary 8-hydroxy-2′-deoxyguanosine excretion with radiotherapy, chemotherapy, and response to treatment. FEBS Lett 1997; 409: 287-291.
17. Leinonen J, Lehtimäki T, Toyokuni S et al. New biomarker evidence of oxidative DNA damage in patients with non-insulindependent diabetes mellitus. FEBS Lett 1997;417: 150-152.
18. 15N] in biological fluids. Anal Biochem 1982; 126: 131-138.
19. Toyokuni S, Tanaka T, Hattori Y et al. Quantitative immunohistochemical determination of 8-hydroxy-2′-deoxyguanosine by a monoclonal antibody N45.1 : Its application to ferric nitrilotriacetate-induced renal carcinogenesis model. Lab Invest 1997; 76: 365-374.
20. Nakamura H, Nakamura K, Yodoi J. Redox regulation of cellular activation. Anna Rev Immunnl 1997; 15: 351-369.
21. Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κ-B transcription factor and HIV-1. EMBO J 1991; 10: 2247-2258.
22. Abate C, Patel L, Rauscher III FJ, Curran T. Redox regulation of Fos and Jun DNA-binding activity in vitro. Science 1990; 249: 1157-1161.
23. Grisham MB, Granger N, Lefer DJ. Modulation of leukocyte-endothelial interactions by reactive metabolites of oxygen and nitrogen: Relevance to ischemic heart disease. Free Radic Biol Med 1998; 25: 404-433.
24. McIntyre M, Bohr DF, Dominiczak AF. Endothelial function in hypertension: the role of Superoxide anion. Hypertension 1999; 34: 539-545.
25. Miles AM, Bohle DS, Glassbrenner PA, Hansert B, Wink DA, Grisham MB. Modulation of superoxide-dependent oxidation of hydroxylation reactions by nitric oxide. J Biol Chem 1996; 271: 40-47.
26. Grunfeld S, Hamilton CA, Mesaros S et al. Role of Superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats. Hypertension 1995; 26: 854-857.
27. Tschudi MR, Mesaros S, Lüscher TF, Malinski T. Direct in situ measurement of nitric oxide in mesenteric resistance arteries: increased decomposition by Superoxide in hypertension. Hypertension 1996; 27: 32-35.
28. Bouloumié A, Bauersachs J, Linz W et al. Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and Superoxide anion production. Hypertension 1997; 30: 934-941.
29. Rajagopalan S, Kurz S, Munzel T et al. Angiotensin II-mediated hypertension in the rat increases vascular Superoxide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone. J Clin Invest 1996; 97: 1916-1923.
30. Oskarsson HJ, Heistad DD. Oxidative stress produced by angiotensin II: implications for hypertension and vascular injury. Circulation 1997; 95: 557-559.