Transcriptional regulation of pituitary synthesis and secretion of growth hormone in growing wethers and the influence of zeranol on these mechanisms

Domestic Animal Endocrinology

Volumn 18, Issue 3, 2000, Pages 309-324

  Thomas, M G ^a   Carroll, J A ^b   Raymond, S R ^c   Matteri, R L ^b   Keisler, D H ^c  

^a NEW MEXICO STATE UNIVERSITY   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

^c UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; ESTROGEN; GROWTH HORMONE; HORMONE RECEPTOR; MESSENGER RNA; NEUROPEPTIDE RECEPTOR; SOMATOMEDIN C; SOMATOTROPIN RELEASING HORMONE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PIT-1; ZERANOL;

ANIMAL; ANIMAL DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BIOSYNTHESIS; BLOOD; BODY WEIGHT; CHEMISTRY; CLUSTER ANALYSIS; CONTROLLED STUDY; DNA PROBE; EXON; FEMALE; GENE EXPRESSION REGULATION; GENETICS; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE RELEASE; HORMONE SYNTHESIS; HYPOPHYSIS; ISOLATION AND PURIFICATION; LAMB; MALE; METABOLISM; NONHUMAN; NUCLEIC ACID HYBRIDIZATION; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RANDOMIZATION; SECRETION; SHEEP; STATISTICAL MODEL; STATISTICS; TRANSCRIPTION REGULATION; WEIGHT GAIN;

ANIMALS; AREA UNDER CURVE; BODY WEIGHT; CLUSTER ANALYSIS; DNA PROBES; DNA-BINDING PROTEINS; ESTROGENS, NON-STEROIDAL; FEMALE; GENE EXPRESSION REGULATION; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR I; LINEAR MODELS; MALE; NUCLEIC ACID HYBRIDIZATION; PITUITARY GLAND; POLYMERASE CHAIN REACTION; RADIOIMMUNOASSAY; RANDOM ALLOCATION; RECEPTORS, NEUROPEPTIDE; RECEPTORS, PITUITARY HORMONE-REGULATING HORMONE; RNA, MESSENGER; SHEEP; STATISTICS, NONPARAMETRIC; TRANSCRIPTION FACTOR PIT-1; TRANSCRIPTION FACTORS; ZERANOL;

ANIMALIA; OVIS ARIES;

EID: 0034118915     PISSN: 07397240     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0739-7240(00)00052-7     Document Type: Article

References (44)

1. Breier B.H., Gluckman P.D., Bass J.J. Influence of nutritional status and oestradiol-17β on plasma growth hormone, insulin-like growth factor-I and -II and the response to exogenous growth hormone in steers. J Endocrinol. 118:1988;243-250.
2. Enright W.J., Quirke J.F., Gluckman P.D., Brier B.H., Kennedy L.G., Hart I.C., Roche J.F., Coert A., Allen P. Effects of long-term administration of pituitary-derived bovine growth hormone and estradiol on growth in steers. J Anim Sci. 68:1990;2345-2356.
3. Williams J.E., Ireland S.H., Mollet T.A., Hancock D.L., Beaver E.E., Hannah S. Influence of zeranol and breed on growth, composition of gain, and plasma hormone concentrations. J Anim Sci. 69:1991;1688-1696.
4. Kerrigan J.R., Rogol A.D. The impact of gonadal steroid hormone action on growth hormone secretion during childhood and adolescence. Endocr Rev. 13:1992;281-298.
5. Wehrenberg W.B., Giustina A. Basic counterpoint Mechanism and pathways of gonadal steroid modulation of growth hormone secretion . Endocr Rev. 13:1992;299-308.
6. Davis S.L., Ohlson D.L., Klindt J., Anfison M.S. Episodic growth hormone secretory pattern in sheep. Relationship to gonadal steroid hormones. Am J Physiol. 233:1977;E519-E523.
7. Phelps C.J., Wiggins J.P., Wangsness P.J. Effects of zeranol on in vitro growth hormone release by lambs and ram pituitary cells. J Anim Sci. 66:1988;2614-2625.
8. Hufstelder G.D., Gillman P.L., Carstens G.E., Greene L.W., Turner N.D. Physiological and hormonal responses of lambs repeatedly implanted with zeranol and provided two levels of feed intake. J Anim Sci. 74:1996;2376-2384.
9. Meyer H.H.D., Rapp M. Estrogen receptor in bovine skeletal muscle. J Anim Sci. 60:1985;294-300.
10. Muir L.A. Mode of action of exogenous substances on animal growth an overview. J. Anim Sci. 61:(suppl 1):1985;1315-1325.
11. Preston R.L. Biological responses to estrogen additives in meat producing cattle and lambs. J Anim Sci. 41:1975;1414-1430.
12. Kineman R.D., Henricks D.M., Fraught W.J., Frawley L.S. Fluctuations in the proportions of growth hormone- and prolactin-secreting cells during the bovine estrous cycle. Endocrinology. 129:1991;1221-1225.
13. Kineman R.D., Fraught W.J., Frawley L.S. Steroids can modulate transdifferentiation of prolactin and growth hormone cells in bovine pituitary cultures. Endocrinology. 130:1992;3289-3294.
14. French JT. Regulation of growth hormone (GH): Effect of Zeranol and Synovex on secretion of GH and accumulation of GH mRNA in the bovine pituitary gland. Dissertation, Texas A&M University, 1991.
15. Tuggle C.K., Trenkle A. Control of growth hormone synthesis. Domest Anim Endocrinol. 13:1996;1-33.
16. Beato M., Sanchez-Pacheco A. Interaction of steroid hormone receptors with the transcription initiation complex. Endo Rev. 17:1996;587-609.
17. Powell M.R., Keisler D.H. A potential strategy for decreasing milk production in the ewe at weaning using a growth hormone release blocker. J Anim Sci. 73:1995;1901-1905.
18. Matteri R.L., Lamberson W.R., Keisler D.H. Relationship between in vitro somatotroph function and growth in three week-old barrows. Domest Anim Endocrinol. 11:1994;363-373.
19. Matteri R.L., Carroll J.A. Somatroph function in the neonatal pig. Domest Anim Endocrinol. 14:1997;241-249.
20. Dyer C.J., Simmons J.M., Matteri R.L., Keisler D.H. cDNA cloning and tissue-specific gene expression of ovine leptin, NPY-Y1, and NPY-Y2 receptor. Domest Anim Endocrinol. 14:1997;295-303.
21. Gill J.D., Hafs H.D. Analysis of repeated measures of animals. J Anim Sci. 33:1971;331-336.
22. SAS. SAS user's guide. Statistics (Version 5). Cary, NC: SAS, 1985.
23. Snedecor GW, Cochran WG. Statistical methods, Cochran GW, editor. Ames, IA Iowa State University Press, 1989.
24. SAS. Using the GLM procedure and the CONTRAST statement: a very basic approach. In: Fulenwinder DO, editor. SAS User's Group International Proceeding of the Fifteenth Annual Conference. Cary, NC: SAS Institute Inc, 1990.
25. Veldhuis J.D., Johnson M.L. Cluster analysis A simple, versatile, and robust algorithm for endocrine pulse detection . Am J Physiol. 250:1986;E486-E493.
26. Olivares V.H., Hallford D.H. Growth and carcass characteristics and serum growth hormone, prolactin, and insulin profiles in Debouillet lambs treated with ovine growth hormone and (or) zeranol. J Anim Sci. 68:1990;1971-1979.
27. McLaughlin, CL, Hedrick HB, Veenhuizen JJ, Finn RF, Hintz RL, Hartnell GF, Kasser TR, Baile CA. Comparison of performance, clinical chemistry, and carcass characteristics of finishing lambs treated with recombinant ovine or bovine somatotropins. J Anim Sci 1993;71:1453-63.
28. McLaughlin C.L., Hedrick H.B., Veenhuizen J.J., Hintz R.L., Munyakazi L., Kasser T.R., Baile C.A. Performance, clinical chemistry, and carcass responses of finishing lambs to formulated sometribove (methionyl bovine somatotropin). J Anim Sci. 72:1994;2544-2551.
29. Roseboom KJ. Body composition and effects of zeranol on lambs. Thesis. University of Missouri, 1997.
30. Frohman L.A. Endocrine and neuroendocrine regulation of cell function and growth. J Anim Sci. 69:(suppl 1):1991;74-81.
31. Klindt J., Ohlson D.L., Davis S.L., Schanbacher B.D. Ontogeny of growth hormone, prolactin, luteinizing hormone, and testosterone secretory patterns in the ram. Biol Reprod. 33:1985;436-444.
32. Aribat T.H., Lapierre H., Dubreuil P., Pelletier G., Gaudreau P., Brazeau P., Petitclerc D. Insulin-like growth factor-I concentration in Holstein female cattle Variations with age, stage of lactation and growth hormone releasing hormone administration . Domest Anim Endocrinol. 7:1990;93-102.
33. Nakamura Y., Usui T., Mizuta H., Murabe H., Muro S., Suda M., Tanaka K., Tanaka I., Shimatsu A., Nakao K. Characterization of prophet of Pit-1 gene expression in normal pituitary and pituitary adenomas in humans. J Clin Endocrinol Metab. 84:1999;1414-1419.
34. Rajas F, Delhase M, De La Hoya M, Verdood P, Castrillo JL, Hooghe-Peters EL. Nuclear factor 1 regulates the distal silencer of the human Pit-1/GHF-1 gene. Biochem J 333:77-84.
35. Sanchez-Pacheco A., Palomino T., Aranda A. Retinoic acid induces expression of the transcription factor GHF-1/Pit-1 in pituitary prolactin- and growth hormone-producing cell lines. Endocrinology. 136:1995;5391-5398.
36. Mancini M.G., Liu B., Sharp Z.D., Mancini M.A. Subnuclear partitioning and functional regulation of the Pit-1 transcription factor. J Cell Biochem. 72:1999;322-338.
37. Nowakowski B.E., Maurer R.A. Multiple Pit-1-binding sites facilitates estrogen responsiveness of the prolactin gene. Mol Endocrinol. 8:1994;1742-1749.
38. Gonzalez-Parra S., Chowen J.A., Garcia-Segura L.M., Argente J. In vivo and in vitro regulation of pituitary transcription factor-1 (Pit-1) by changes in hormone environment. Neuroendocrinology. 63:1996;3-15.
39. Gonzalez-Parra S., Argente J., Garcia-Segura L.M., Chowen J.A. Cellular composition of the adult rat anterior pituitary is influenced by neonatal sex steroid environment. Neuroendocrinology. 68:1998;152-162.
40. Lee B.J., Kim J.H., Kang H.M., Kim H.C., Kang S.G. Changes in mRNA levels of a pituitary transcription factor, Pit-1, and prolactin during the rat estrous cycle. Euro J Endo. 132:1995;771-776.
41. Mastri C., Sloop T.C., Lucier G.W. Nuclear interactions of zearalanol-oestrogen receptor complexes in rat liver A comparison with estradiol-17β J Steroid Biochem. 24:1986;519-523.
42. Katzenellenbogen JA, O'Malley, Katzenellenbogen BS. Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter specific action of these hormones. Mol Endocrinol 1996;10:119-31.
43. Kuiper G.G.J.M., Carlsson B., Grandien K., Enmark E., Haggblad H., Nilson S., Gustafsson J.A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptor α and β Endocrinology. 138:1997;863-870.
44. Carroll JA. Pituitary gland development and somatotroph function in domestic livestock. Dissertation. Texas A&M University, 1996.