메뉴 건너뛰기




Volumn 7, Issue 3, 2000, Pages 438-445

Gene therapy of metastatic colon carcinoma: Regression of multiple hepatic metastases by adenoviral expression of bacterial cytosine deaminase

Author keywords

5 fluorocytosine; BALB c; Cancer gene therapy; Colon carcinoma; Cytosine deaminase; Mice

Indexed keywords

ANTINEOPLASTIC AGENT; BACTERIAL ENZYME; CYTOSINE DEAMINASE; FLUOROURACIL; VIRUS VECTOR;

EID: 0034117830     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700131     Document Type: Article
Times cited : (30)

References (36)
  • 2
    • 0023854339 scopus 로고
    • Resection of the liver for colorectal carcinoma metastases: A multi-institutional study of long-term survivors
    • Hughes KS, Rosenstein RB, Songhorabodi S, et al. Resection of the liver for colorectal carcinoma metastases: a multi-institutional study of long-term survivors. Dis Colon Rectum. 1988;31:1-4.
    • (1988) Dis Colon Rectum , vol.31 , pp. 1-4
    • Hughes, K.S.1    Rosenstein, R.B.2    Songhorabodi, S.3
  • 3
    • 0029685352 scopus 로고    scopus 로고
    • Surgical resection of pulmonary metastases from colorectal carcinoma: Five-year survival and main prognostic factors
    • Baron O, Amini M, Duveau D, Despins P, Sagan CA, Michaud JL. Surgical resection of pulmonary metastases from colorectal carcinoma: five-year survival and main prognostic factors. Eur J Cardiothorac Surg. 1996;10:347-351.
    • (1996) Eur J Cardiothorac Surg , vol.10 , pp. 347-351
    • Baron, O.1    Amini, M.2    Duveau, D.3    Despins, P.4    Sagan, C.A.5    Michaud, J.L.6
  • 4
    • 0343847039 scopus 로고    scopus 로고
    • Malignant neoplasms of the large intestine, chemotherapy
    • Feldman M, Scharschmidt BF, Sleisenger MH, eds. Philadelphia: WB Saunders
    • Bresalier RS, Kim YS. Malignant neoplasms of the large intestine, chemotherapy. In: Feldman M, Scharschmidt BF, Sleisenger MH, eds. Gastrointestinal and Liver Disease. 6 ed. Philadelphia: WB Saunders; 1998:1935-1938.
    • (1998) Gastrointestinal and Liver Disease. 6 Ed. , pp. 1935-1938
    • Bresalier, R.S.1    Kim, Y.S.2
  • 6
    • 0026568864 scopus 로고
    • Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase
    • Danielsen S, Kilstrup M, Barilla K, Jochimsen B, Neuhard J. Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase. Mol Microbiol. 1992;6:1335-1344.
    • (1992) Mol Microbiol , vol.6 , pp. 1335-1344
    • Danielsen, S.1    Kilstrup, M.2    Barilla, K.3    Jochimsen, B.4    Neuhard, J.5
  • 7
    • 0027496518 scopus 로고
    • In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase
    • Huber BE, Austin EA, Good SS, Knick VC, Tibbels S, Richards CA. In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase. Cancer Res. 1993;53:4619-4626.
    • (1993) Cancer Res , vol.53 , pp. 4619-4626
    • Huber, B.E.1    Austin, E.A.2    Good, S.S.3    Knick, V.C.4    Tibbels, S.5    Richards, C.A.6
  • 8
    • 0027260609 scopus 로고
    • Packaging capacity and stability of human adenovirus type 5 vectors
    • Bett AJ, Prevec L, Graham FL. Packaging capacity and stability of human adenovirus type 5 vectors. J Virol. 1993;67:5911-5921.
    • (1993) J Virol , vol.67 , pp. 5911-5921
    • Bett, A.J.1    Prevec, L.2    Graham, F.L.3
  • 9
    • 0028559768 scopus 로고
    • An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3
    • Bett AJ, Haddara W, Prevec L, Graham FL. An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc Natl Acad Sci USA. 1994;91:8802-8806.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8802-8806
    • Bett, A.J.1    Haddara, W.2    Prevec, L.3    Graham, F.L.4
  • 10
    • 0021770224 scopus 로고
    • Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs
    • Kozak M. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res. 1984;12:857-872.
    • (1984) Nucleic Acids Res , vol.12 , pp. 857-872
    • Kozak, M.1
  • 11
    • 0015857646 scopus 로고
    • Transformation of rat cells by DNA of human adenovirus 5
    • Graham FL, van der Eb AJ. Transformation of rat cells by DNA of human adenovirus 5. Virology. 1973;54:536-539.
    • (1973) Virology , vol.54 , pp. 536-539
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 12
    • 0026906987 scopus 로고
    • Adenovirus-mediated in vivo gene transfer and expression in normal rat liver
    • Jaffe HA, Danel C, Longenecker G, et al. Adenovirus-mediated in vivo gene transfer and expression in normal rat liver. Nat Genet. 1992;1:372-378.
    • (1992) Nat Genet , vol.1 , pp. 372-378
    • Jaffe, H.A.1    Danel, C.2    Longenecker, G.3
  • 13
    • 0030686481 scopus 로고    scopus 로고
    • Adenoviral-mediated herpes simplex virus thymidine kinase gene transfer: Regression of hepatic metastasis of pancreatic tumors
    • Block A, Chen SH, Kosai KI, Finegold M, Woo SLC. Adenoviral-mediated herpes simplex virus thymidine kinase gene transfer: regression of hepatic metastasis of pancreatic tumors. Pancreas. 1997;15:25-34.
    • (1997) Pancreas , vol.15 , pp. 25-34
    • Block, A.1    Chen, S.H.2    Kosai, K.I.3    Finegold, M.4    Woo, S.L.C.5
  • 14
    • 0022506890 scopus 로고
    • Rapid chemosensitivity testing of human lung tumor cells using the MTT assay
    • Cole SP. Rapid chemosensitivity testing of human lung tumor cells using the MTT assay. Cancer Chemother Pharmacol. 1986;17:259-263.
    • (1986) Cancer Chemother Pharmacol , vol.17 , pp. 259-263
    • Cole, S.P.1
  • 15
    • 0023130372 scopus 로고
    • Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
    • Carmichael J, DcGraff WG, Gazdar AF, Minna JD, Mitchell JB. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res. 1987;47:936-942.
    • (1987) Cancer Res , vol.47 , pp. 936-942
    • Carmichael, J.1    Dcgraff, W.G.2    Gazdar, A.F.3    Minna, J.D.4    Mitchell, J.B.5
  • 16
    • 0023619677 scopus 로고
    • A study of some variables in a tetrazolium dye (MTT)-based assay for cell growth and chemosensitivity
    • Twentyman PR, Luscombe M. A study of some variables in a tetrazolium dye (MTT)-based assay for cell growth and chemosensitivity. Br J Cancer. 1987;56:279-285.
    • (1987) Br J Cancer , vol.56 , pp. 279-285
    • Twentyman, P.R.1    Luscombe, M.2
  • 17
    • 0022988979 scopus 로고
    • Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos
    • Sanes JR, Rubenstein JL, Nicolas JF. Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J. 1986;5:3133-3142.
    • (1986) EMBO J , vol.5 , pp. 3133-3142
    • Sanes, J.R.1    Rubenstein, J.L.2    Nicolas, J.F.3
  • 18
    • 0025298715 scopus 로고
    • Activation of a β-galactosidase recombinant provirus: Application to titration of human immunodeficiency virus (HIV) and HIV-infected cells
    • Rocancourt D, Bonnerot C, Jouin H, Emerman M, Nicolas JF. Activation of a β-galactosidase recombinant provirus: application to titration of human immunodeficiency virus (HIV) and HIV-infected cells. J Virol. 1990;64:2660-2668.
    • (1990) J Virol , vol.64 , pp. 2660-2668
    • Rocancourt, D.1    Bonnerot, C.2    Jouin, H.3    Emerman, M.4    Nicolas, J.F.5
  • 20
    • 0001543287 scopus 로고
    • Phase II study of prolonged infusion of 5-fluorouracil with weekly leucovorin in disseminated colorectal cancer
    • Leichman CG, Leichman L, Spears CP, Rosen P, Jeffers S. Phase II study of prolonged infusion of 5-fluorouracil with weekly leucovorin in disseminated colorectal cancer. Proc Am Soc Clin Oncol. 1991;10:143-147.
    • (1991) Proc Am Soc Clin Oncol , vol.10 , pp. 143-147
    • Leichman, C.G.1    Leichman, L.2    Spears, C.P.3    Rosen, P.4    Jeffers, S.5
  • 21
    • 0001483628 scopus 로고
    • A controlled multicentric trial of intrahepatic artery chemotherapy versus standard palliative treatment for colorectal liver metastases
    • Rougier P, Hay JM, Olivier JM. A controlled multicentric trial of intrahepatic artery chemotherapy versus standard palliative treatment for colorectal liver metastases. Proc Am Soc Clin Oncol. 1990;9:104-108.
    • (1990) Proc Am Soc Clin Oncol , vol.9 , pp. 104-108
    • Rougier, P.1    Hay, J.M.2    Olivier, J.M.3
  • 22
    • 0028905561 scopus 로고
    • Combination gene therapy for liver metastasis of colon carcinoma in vivo
    • Chen SH, Chen XH, Wang Y, et al. Combination gene therapy for liver metastasis of colon carcinoma in vivo. Proc Natl Acad Sci USA. 1995;92:2577-2581.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2577-2581
    • Chen, S.H.1    Chen, X.H.2    Wang, Y.3
  • 23
    • 0031031069 scopus 로고    scopus 로고
    • Effect of gene therapy with the herpes simplex virus-thymidine kinase gene on hepatic metastasis in murine colon cancer
    • Hayashi S, Emi N, Yokoyama I, Uchida K, Takagi H. Effect of gene therapy with the herpes simplex virus-thymidine kinase gene on hepatic metastasis in murine colon cancer. Surg Today. 1997;27:40-43.
    • (1997) Surg Today , vol.27 , pp. 40-43
    • Hayashi, S.1    Emi, N.2    Yokoyama, I.3    Uchida, K.4    Takagi, H.5
  • 24
    • 0027523517 scopus 로고
    • A first step in the development of gene therapy for colorectal carcinoma: Cloning, sequencing, and expression of Escherichia coli cytosine deaminase
    • Austin EA, Huber BE. A first step in the development of gene therapy for colorectal carcinoma: cloning, sequencing, and expression of Escherichia coli cytosine deaminase. Mol Pharmacol. 1993;43:380-387.
    • (1993) Mol Pharmacol , vol.43 , pp. 380-387
    • Austin, E.A.1    Huber, B.E.2
  • 25
    • 0024262909 scopus 로고
    • Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule
    • Van Groeningen CJ, Pinedo HM, Heddes J. Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule. Cancer Res. 1988;48:6956-6961.
    • (1988) Cancer Res , vol.48 , pp. 6956-6961
    • Van Groeningen, C.J.1    Pinedo, H.M.2    Heddes, J.3
  • 26
    • 0026793052 scopus 로고
    • Purification and characterization of dihydropyrimidine dehydrogenase from human liver
    • Lu Z, Zhang R, Diasio RB. Purification and characterization of dihydropyrimidine dehydrogenase from human liver. J Biol Chem. 1992;267:17102-17109.
    • (1992) J Biol Chem , vol.267 , pp. 17102-17109
    • Lu, Z.1    Zhang, R.2    Diasio, R.B.3
  • 27
    • 0030920487 scopus 로고    scopus 로고
    • Adenovirale gentherapie bei lebermetastasen gastrointestinaler tumoren
    • Block A, Windler E, Greten H, Woo SLC. Adenovirale Gentherapie bei Lebermetastasen gastrointestinaler Tumoren. Dtsch Med Wochenschr. 1997;122:728-732.
    • (1997) Dtsch Med Wochenschr , vol.122 , pp. 728-732
    • Block, A.1    Windler, E.2    Greten, H.3    Woo, S.L.C.4
  • 28
    • 0030009774 scopus 로고    scopus 로고
    • Liver-directed gene transfer and application to therapy
    • Sandig V, Strauss M. Liver-directed gene transfer and application to therapy. J Mol Med. 1996;74:205-212.
    • (1996) J Mol Med , vol.74 , pp. 205-212
    • Sandig, V.1    Strauss, M.2
  • 29
    • 0028168641 scopus 로고
    • Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis
    • Crystal RG, McElvaney NG, Rosenfeld MA, et al. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nat Genet. 1994;8:42-51.
    • (1994) Nat Genet , vol.8 , pp. 42-51
    • Crystal, R.G.1    McElvaney, N.G.2    Rosenfeld, M.A.3
  • 30
    • 0029740524 scopus 로고    scopus 로고
    • Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: Sustained antitumor immunity prolongs animal survival
    • Chen SH, Kosai K, Xu B, et al. Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival. Cancer Res. 1996;56:3758-3762.
    • (1996) Cancer Res , vol.56 , pp. 3758-3762
    • Chen, S.H.1    Kosai, K.2    Xu, B.3
  • 31
    • 0029859405 scopus 로고    scopus 로고
    • Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma
    • Caruso M, Pham-Nguyen K, Kwong YL, et al. Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma. Proc Natl Acad Sci USA. 1996;93:11302-11306.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 11302-11306
    • Caruso, M.1    Pham-Nguyen, K.2    Kwong, Y.L.3
  • 32
    • 0031975745 scopus 로고    scopus 로고
    • The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses
    • Bergelson JM, Krithivas A, Celi L, et al. The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses. J Virol. 1998;72:415-419.
    • (1998) J Virol , vol.72 , pp. 415-419
    • Bergelson, J.M.1    Krithivas, A.2    Celi, L.3
  • 33
    • 0032212265 scopus 로고    scopus 로고
    • The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures
    • Hemmi S, Geertsen R, Mezzacasa A, Peter I, Dummer R. The presence of human coxsackievirus and adenovirus receptor is associated with efficient adenovirus-mediated transgene expression in human melanoma cell cultures. Hum Gene Ther. 1998;9:2363-2373.
    • (1998) Hum Gene Ther , vol.9 , pp. 2363-2373
    • Hemmi, S.1    Geertsen, R.2    Mezzacasa, A.3    Peter, I.4    Dummer, R.5
  • 34
    • 0028987384 scopus 로고
    • 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery
    • 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery. J Virol. 1995;69:2257-2263.
    • (1995) J Virol , vol.69 , pp. 2257-2263
    • Huang, S.1    Endo, R.I.2    Nemerow, G.R.3
  • 36
    • 0029822002 scopus 로고    scopus 로고
    • Adenovirus-mediated hepatic gene transfer in mice: Comparison of intravascular and biliary administration
    • Peeters MJ, Patijn GA, Lieber A, Meuse L, Kay MA. Adenovirus-mediated hepatic gene transfer in mice: comparison of intravascular and biliary administration. Hum Gene Ther. 1996;7:1693-1699.
    • (1996) Hum Gene Ther , vol.7 , pp. 1693-1699
    • Peeters, M.J.1    Patijn, G.A.2    Lieber, A.3    Meuse, L.4    Kay, M.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.