메뉴 건너뛰기




Volumn 27, Issue 5, 2000, Pages 475-484

Evaluation of [O-methyl-11C]RS.15385-197 as a positron emission tomography radioligand for central α2-adrenoceptors

Author keywords

Positron emission tomography; RS 15385 197; RS 79948 197; 2 adrenoceptor

Indexed keywords

12 ETHYLSULFONYL 5,8,8A,9,10,11,12,12A,13,13A DECAHYDRO 3 METHOXY 6H ISOQUINO[2,1 G][1,6]NAPHTHYRIDINE; 5,8,8A,9,10,11,12,12A,13,13A DECAHYDRO 3 METHOXY 12 (ETHYLSULFONYL) 6H ISOQUINOL[2,1 G][1,6]NAPHYRIDINE; ALPHA 2 ADRENERGIC RECEPTOR; CARBON 11; DELEQUAMINE; DELEQUAMINE C 11; DRUG METABOLITE; RADIOLIGAND; TRITIUM; UNCLASSIFIED DRUG;

EID: 0034116218     PISSN: 03406997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002590050531     Document Type: Article
Times cited : (20)

References (28)
  • 8
    • 0026101435 scopus 로고
    • Structure-affinity relationships of the 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1,6]naphthyridines at α-adrenoceptors
    • 8. Clark RD, Repke DB, Berger J, Nelson JT, Kilpatrick AT, Brown CM, MacKinnon AC, Clague RU, Spedding M. Structure-affinity relationships of the 12-sulfonyl derivatives of 5,8,8a,9,10,11,12,12a,13,13a-decahydro-6H-isoquino[2,1-g][1,6]naphthyridines at α-adrenoceptors. J Med Chem 1991; 34: 705-717.
    • (1991) J Med Chem , vol.34 , pp. 705-717
    • Clark, R.D.1    Repke, D.B.2    Berger, J.3    Nelson, J.T.4    Kilpatrick, A.T.5    Brown, C.M.6    Mackinnon, A.C.7    Clague, R.U.8    Spedding, M.9
  • 10
    • 0003165169 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of [F-18]RS-15385-FP: A potent and selective alpha-2 adrenergic receptor radioligand for PET
    • 40P.
    • 10. Enas JD, Clark RD, VanBrocklin HF, Biegon A, Hanrahan SM, Budinger TF. Synthesis and biological evaluation of [F-18]RS-15385-FP: a potent and selective alpha-2 adrenergic receptor radioligand for PET. J Nucl Med 1996; 37: 40P.
    • (1996) J Nucl Med , vol.37
    • Enas, J.D.1    Clark, R.D.2    VanBrocklin, H.F.3    Biegon, A.4    Hanrahan, S.M.5    Budinger, T.F.6
  • 13
    • 0016671063 scopus 로고
    • Kinetics of blood-brain barrier transport of hexoses
    • 13. Pardridge WM, Oldendorf WH. Kinetics of blood-brain barrier transport of hexoses. Biochem Biophys Acta 1975; 382: 377-392.
    • (1975) Biochem Biophys Acta , vol.382 , pp. 377-392
    • Pardridge, W.M.1    Oldendorf, W.H.2
  • 15
    • 0026328315 scopus 로고
    • The on-line monitoring of continuously withdrawn arterial blood during PET studies using a single BGO photomultiplier assembly and non-stick tubing
    • 15. Ranicar ASO, Williams CW, Schnorr L, Clark JC, Rhodes CG, Bloomfield PM, Jones T. The on-line monitoring of continuously withdrawn arterial blood during PET studies using a single BGO photomultiplier assembly and non-stick tubing. Med Prog Technol 1991; 17: 259-264.
    • (1991) Med Prog Technol , vol.17 , pp. 259-264
    • Ranicar, A.S.O.1    Williams, C.W.2    Schnorr, L.3    Clark, J.C.4    Rhodes, C.G.5    Bloomfield, P.M.6    Jones, T.7
  • 16
    • 0029797912 scopus 로고    scopus 로고
    • Correction for scatter in 3D brain PET using a dual energy window method
    • 16. Grootoonk S, Spinks TJ, Sashin D, Spyrou NM, Jones T. Correction for scatter in 3D brain PET using a dual energy window method. Phys Med Biol 1996; 41: 2757-2774.
    • (1996) Phys Med Biol , vol.41 , pp. 2757-2774
    • Grootoonk, S.1    Spinks, T.J.2    Sashin, D.3    Spyrou, N.M.4    Jones, T.5
  • 17
    • 0024610693 scopus 로고
    • Analytical 3-D image reconstruction using all detected events
    • 17. Kinahan PE, Rogers JG. Analytical 3-D image reconstruction using all detected events. IEEE Trans Nucl Sci 1989; NS-36: 964-968.
    • (1989) IEEE Trans Nucl Sci , vol.NS-36 , pp. 964-968
    • Kinahan, P.E.1    Rogers, J.G.2
  • 18
    • 0026124864 scopus 로고
    • A software system for interactive and quantitative visualization of multidimensional biomedical images
    • 18. Robb RA, Hanson DP. A software system for interactive and quantitative visualization of multidimensional biomedical images. Aust Phys Eng Sci Med 1991; 14: 9-30.
    • (1991) Aust Phys Eng Sci Med , vol.14 , pp. 9-30
    • Robb, R.A.1    Hanson, D.P.2
  • 19
    • 0031028413 scopus 로고    scopus 로고
    • Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures
    • 19. Studholme C, Hill DLG, Hawkes DJ. Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures. Med Phys 1997; 24: 25-35.
    • (1997) Med Phys , vol.24 , pp. 25-35
    • Studholme, C.1    Hill, D.L.G.2    Hawkes, D.J.3
  • 22
    • 0031279782 scopus 로고    scopus 로고
    • Parametric imaging of ligand-receptor binding in PET using a simplified reference region model
    • 22. Gunn RN, Lammertsma AA, Hume SP, Cunningham VJ. Parametric imaging of ligand-receptor binding in PET using a simplified reference region model. Neuroimage 1997; 6: 279-287.
    • (1997) Neuroimage , vol.6 , pp. 279-287
    • Gunn, R.N.1    Lammertsma, A.A.2    Hume, S.P.3    Cunningham, V.J.4
  • 23
    • 0030869387 scopus 로고    scopus 로고
    • In vivo saturation kinetics of two dopamine transporter probes measured using a small animal positron emission tomography scanner
    • 23. Hume SP, Brown DJ, Ashworth S, Hirani E, Luthra SK, Lammertsma AA. In vivo saturation kinetics of two dopamine transporter probes measured using a small animal positron emission tomography scanner. J Neurosci Methods 1997; 76: 45-51.
    • (1997) J Neurosci Methods , vol.76 , pp. 45-51
    • Hume, S.P.1    Brown, D.J.2    Ashworth, S.3    Hirani, E.4    Luthra, S.K.5    Lammertsma, A.A.6
  • 24
    • 0023684053 scopus 로고
    • 2-adrenoceptors: Pharmacological and molecular biologic evidence converge
    • 2-adrenoceptors: pharmacological and molecular biologic evidence converge. Trends Pharmacol Sci 1988; 9: 356-361.
    • (1988) Trends Pharmacol Sci , vol.9 , pp. 356-361
    • Bylund, D.B.1
  • 27
    • 0031472588 scopus 로고    scopus 로고
    • Role of pharmacokinetics and metabolism in drug discovery and development
    • 27. Lin JH, Lu AYH. Role of pharmacokinetics and metabolism in drug discovery and development. Pharmacol Rev 1997; 49: 403-450.
    • (1997) Pharmacol Rev , vol.49 , pp. 403-450
    • Lin, J.H.1    Lu, A.Y.H.2
  • 28
    • 0023688512 scopus 로고
    • Effects of the binding of imipramine to erythrocytes and plasma proteins on its transport through the rat blood-brain barrier
    • 28. Riant P, Urien S, Albengres E, Renouard A, Tillement JP. Effects of the binding of imipramine to erythrocytes and plasma proteins on its transport through the rat blood-brain barrier. J Neurochem 1988; 58: 421-425.
    • (1988) J Neurochem , vol.58 , pp. 421-425
    • Riant, P.1    Urien, S.2    Albengres, E.3    Renouard, A.4    Tillement, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.