Switching intracellular signaling pathways to study sphingosine 1-phosphate receptors

Annals of the New York Academy of Sciences

Volumn 905, Issue , 2000, Pages 260-262

  Ancellin, Nicolas ^a   Hla, Timothy ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECEPTOR; SPHINGOSINE 1 PHOSPHATE;

CONFERENCE PAPER; FEMALE; OOCYTE; SIGNAL TRANSDUCTION;

EID: 0034113311     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06555.x     Document Type: Conference Paper

References (9)

1. 1. SPIEGEL, S. & A.M. MERRILL, JR. 1996. Sphingolípid metabolism and cell growth regulation. FASEB. J. 10: 1388-1397.
2. 2. GOETZL, E.J., et al. 1999. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J. 12: 1589-1598.
3. 3. AN, S., et al. 1999. Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate. J. Cell. Biochem. 30(Suppl.): 1-11.
4. 4. HLA, T., et al. 1999. Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger? Biochem. Pharmacol. 58: 201-207.
5. 5. HLA, T. & T. MACIAG. 1990. An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein coupled receptors. J. Biol. Chem. 265: 9308-9313.
6. 6. YAMAGUCHI, F., et al. 1996. Molecular cloning of the novel G-protein coupled receptor (GPCR) gene mapped on chromosome 9. Biochem. Biophys. Res. Commun. 227: 608-614.
7. 7. MACLENNAN, A.J., et al. 1994. Cloning and characterization of a putative G-protein coupled receptor potentially involved in development. Mol. Cell. Neurosci. 5: 201-209.
8. 8. ANCELLIN, N., et al. 1998. Homologous and heterologous acute desensitization of vasopressin Via receptor in Xenopus oocytes. Cell. Signalling 10: 217-223.
9. 9. CONKLIN, B.R., et al. 1993. Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha. Nature 363: 274-276.