Kinetics of a model nucleoside (guanosine) release from biodegradable poly(DL-lactide-co-glycolide) microspheres: A delivery system for long-term intraocular delivery

Pharmaceutical Development and Technology

Volumn 5, Issue 2, 2000, Pages 279-285

  Chowdhury, Dipak K ^a   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

In vitro in vivo correlation; Microspheres; Particle size; Poly(DL lactide co glycolide); Release rates; Vitreous fluid

Indexed keywords

GUANOSINE; MICROSPHERE; POLYGLACTIN;

ANIMAL EXPERIMENT; ARTICLE; BIODEGRADATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; INFRARED SPECTROSCOPY; KINETICS; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; BUFFERS; CHEMISTRY, PHYSICAL; DEXTRANS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FLUORESCEIN-5-ISOTHIOCYANATE; GUANOSINE; KINETICS; LACTIC ACID; MALE; MICRODIALYSIS; MICROSPHERES; OPHTHALMIC SOLUTIONS; PARTICLE SIZE; PHOSPHATES; POLYGLYCOLIC ACID; POLYMERS; RABBITS; SOLUBILITY; SURFACE PROPERTIES; VITREOUS BODY;

EID: 0034112025     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-100100542     Document Type: Article

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