Effect of maternal cholestasis on bile acid transfer across the rat placenta-maternal liver tandem

Hepatology

Volumn 31, Issue 4, 2000, Pages 975-983

  Macias, Rocio I R ^a   Pascual, Maria J ^a   Bravo, Ana ^b   Alcalde, Maria P ^a   Larena, Monica G ^a   St Pierre, Marie V ^c   Serrano, Maria A ^a   Marin, Jose J G ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b Pneumology Unit   (Spain)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; GLYCOCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT OBSTRUCTION; BILE FLOW; CHOLESTASIS; CONTROLLED STUDY; MEMBRANE VESICLE; NONHUMAN; PLACENTA FUNCTION; PLACENTAL TRANSFER; PRIORITY JOURNAL; RAT;

EID: 0034110028     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/he.2000.5921     Document Type: Article

References (20)

1. Watkins JB. Placental transport: bile acid conjugation and sulfation in the fetus. J Pediatr Gastroenterol Nutr 1983;2:365-373.
2. Iioka H, Moriyama IS, Hino K, Ichijo M. A study on human placental bile acid transport system of taurocholate across microvillous membrane. Acta Obst Gynaec Jpn 1986;38:837-844.
3. Dumaswala R, Setchell KDR, Moyer MS, Suchy FJ. An anion exchanger mediates bile acid transport across the placental microvillous membrane. Am J Physiol 1993;264:G1016-G1023.
4. Marin JJG, Serrano MA, El-Mir MYA, Eleno N, Boyd CAR. Bile acid transport by basal plasma membrane vesicles of human term placental trophoblast. Gastroenterology 1990;99:1431-1438.
5. Marin JJG, Bravo P, El-Mir MYA, Serrano MA. ATP-dependent bile acid transport across microvillous membrane of human term trophoblast. Am J Physiol 1995;31:G685-G694.
6. Cabral DJ, Small DM, Lilly HS, Hamilton JA. Transbilayer movement of bile acids in model membranes. Biochemistry 1987;26:1801-1804.
7. El-Mir MYA, Eleno N, Serrano MA, Bravo P, Marin JJG. Bicarbonate-induced activation of taurocholate transport across the basal plasma membrane of the human term trophoblast. Am J Physiol 1991;260:G887-G894.
8. Serrano MA, Bravo P, El-Mir MYA, Marin JJG. Influence of hydroxylation and conjugation in cross-inhibition of bile acid transport across the human trophoblast basal membrane. Biochim Biophys Acta 1993;1151:28-34.
9. Bravo P, El-Mir MYA, Serrano MA, Boyd CAR, Marin JJG. Interaction between cholephilic anions and bile acid transport across basal membrane of human trophoblast. Am J Physiol 1993;265:G242-G250.
10. Monte MJ, Rodriguez-Bravo T, Macias RIR, Bravo P, El-Mir MYA, Serrano MA, Lopez-Salva A, et al. Relationship between bile acid transplacental gradients and transport across the fetal-facing plasma membrane of the human trophoblast. Pediatric Res 1995;38:156-163.
11. Trauner M, Meier PJ, Boyer JL. Molecular pathogenesis of cholestasis. N Engl J Med 1998;339:1217-1227.
12. St-Pierre MV, Serrano MA, Lauper U, Marin JJG, Meier PJ. Identification of bile salt transporters in human and rat placenta [Abstract]. Placenta 1999;20:A62.
13. Serrano MA, Brites D, Larena MG, Monte MJ, Bravo P, Oliveira N, Marin JJG. Beneficial effect of ursodeoxycholic acid on alterations induced by cholestasis of pregnancy in bile acid transport across the human placenta. J Hepatol 1998;28:829-839.
14. Monte MJ, Morales AI, Arevalo M, Alvaro I, Macias RIR, Marin JJG. Reversible impairment of neonatal hepatobiliary function by maternal cholestasis. HEPATOLOGY 1996;23:1208-1217.
15. El-Mir MY, Monte MJ, Morales AI, Arevalo M, Serrano MA, Marin JJG. Effect of maternal cholestasis on biliary lipid and bile acid secretion in the infant rat. HEPATOLOGY 1997;26:527-536.
16. Talalay P. Enzymatic analysis of steroid hormones. Meth Biochem Anal 1960;8:119-143.
17. Briz O, El-Mir MYA, Bravo P, Villanueva GR, Marin JJG. Fetal excretion of the fluorescent bile acid derivative cholylglycylamido-fluorescein (FITC-GC) by the rat placenta-maternal liver tandem. Placenta 1998;19:119-126.
18. Khanduja KL, Dogra SC. An alternative protein precipitation method for antipyrine estimation in plasma. Clin Chim Acta 1983;135:95-98.
19. Brodie BB, Axelrod J, Soberman R, Levy BB. The estimation of antipyrine in biological materials. J Biol Chem 1949;179:25-29.
20. Smith CH, Nelson DM, King BF, Donohue TM, Ruzycki SM, Kelley LK. Characterization of a microvillous membrane preparation from human placental syncytiotrophoblast: a morphologic, biochemical and physiological study. Am J Obstet Gynecol 1977;128:190-195.