Antagonist properties of the novel antipsychotic, S16924, at cloned, human serotonin 5-HT(2C) receptors: A parallel phosphatidylinositol and calcium accumulation comparison with clozapine and haloperidol

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 361, Issue 5, 2000, Pages 549-554

  Cussac, D ^a   Newman Tancredi, A ^a   Nicolas, J P ^a   Boutin, J A ^a   Millan, M J ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

5 HT(2C) receptors; Antipsychotic; Clozapine; Haloperidol; Phosphatidylinositol; Phospholipase C; Schizophrenia

Indexed keywords

ALPHA [1 [2 (1,4 BENZODIOXAN 5 YLOXY)ETHYL] 3 PYRROLIDINYL] 4 FLUOROACETOPHENONE; CALCIUM; CLOZAPINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; NEUROLEPTIC AGENT; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE C; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CHO CELL; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; NONHUMAN; PROTEIN CONTENT; PSYCHOPHARMACOLOGY; RECEPTOR AFFINITY; SCHIZOPHRENIA;

ANIMALS; ANTIPSYCHOTIC AGENTS; CALCIUM; CHO CELLS; CLOZAPINE; CRICETINAE; HALOPERIDOL; HUMANS; PHOSPHATIDYLINOSITOLS; PYRROLIDINES; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; TRANSFECTION; TRITIUM;

EID: 0034104402     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000221     Document Type: Article

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