Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization

Journal of Cell Biology

Volumn 136, Issue 6, 1997, Pages 1271-1286

  Buczynski, Greg ^a   Grove, Bryon ^a   Nomura, Anson ^d   Kleve, Maurice ^b,c   Bush, John ^b   Firtel, Richard A ^d   Cardelli, James ^a  

^a LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

^b University of Arkansas   (United States)

^c UNIVERSITY OF ARKANSAS AT LITTLE ROCK   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITIDE 3 KINASE; UNCLASSIFIED DRUG;

ARTICLE; CELL MOTILITY; CELL PROLIFERATION; CELL SHAPE; CELL STRUCTURE; CYTOSKELETON; DICTYOSTELIUM DISCOIDEUM; ENDOCYTOSIS; GENE ACTIVITY; GENE FUNCTION; INTRACELLULAR TRANSPORT; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; BIOLOGICAL TRANSPORT; CHEMOTAXIS; CYTOSKELETON; DICTYOSTELIUM; ENDOCYTOSIS; FUNGAL PROTEINS; LYSOSOMES; MAMMALS; PHAGOCYTOSIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PINOCYTOSIS; PROTOZOAN PROTEINS; VACUOLES;

DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM; MAMMALIA;

EID: 0030764770     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.136.6.1271     Document Type: Article

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