High sensitivity bioassay of paralytic (PSP) and amnesic (ASP) algal toxins based on the fluorimetric detection of [Ca2+](i) in rat cortical primary cultures

Toxicon

Volumn 38, Issue 9, 2000, Pages 1283-1297

  Beani, L ^a   Bianchi, C ^a   Guerrini, F ^b   Marani, L ^a   Pistocchi, R ^b   Tomasini, M C ^a   Ceredi, A ^c   Milandri, A ^c   Poletti, R ^c   Boni, L ^b  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c Centro Ricerche Marine   (Italy)

Author keywords

Algal toxins; Cortical neuronal cultures; Intracellular calcium

Indexed keywords

6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ACETIC ACID; AMPA RECEPTOR ANTAGONIST; CALCIUM ION; DOMOIC ACID; FURA 2; GONYAUTOXIN; KAINIC ACID RECEPTOR ANTAGONIST; MARINE TOXIN; SAXITOXIN; TETRODOTOXIN;

ALEXANDRIUM LUSITANICUM; ALGA; AMNESIA; ANIMAL CELL; ARTICLE; BIOASSAY; BRAIN CORTEX; BRAIN NERVE CELL; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; ELECTROSTIMULATION; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NERVE CELL CULTURE; NEWBORN; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; RAT;

ALGAE; ALGAL PROTEINS; AMNESIA; ANIMALS; BIOLOGICAL ASSAY; BRAIN CHEMISTRY; CALCIUM; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSOL; ELECTRIC STIMULATION; EXCITATORY AMINO ACID AGONISTS; FLUORESCENT DYES; NEURONS; NEUROTOXINS; PARALYSIS; RATS; SODIUM CHANNEL BLOCKERS; SPECTROMETRY, FLUORESCENCE;

ALEXANDRIUM LUSITANICUM; ALGAE;

EID: 0034101599     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(99)00230-5     Document Type: Article

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